HTS Libraries

1. HTS Libraries High Throughput Screening (HTS) is a scientific method that sets foot in chemistry and biology, and shows a significant importance in drug discovery. Beginning in the 1980s, the HTS concept heralded a new era of drug discovery, which was accepted by the pharmaceutical industry. In HTS, it is possible for researchers to rapidly perform tens of pharmacological, chemical, genetic texts by using sensitive probes, robotic technology, liquid processing processing/control software. Through this process, researchers can quickly identify active compounds, antibodies, or genes that regulate a specific biological pathway. The results of these experiments would provide a starting point for drug design and enable us to understand the interactions or roles of specific biochemical processes in drug discovery. devices and data BOC Sciences provides HTS libraries containing a collection of over 600000 compounds. All compounds from BOC Sciences’ HTS libraries are distinguished as lead-like and drug-like chemical entities. These compounds are classified by BOC Sciences into several parts for the convenience of HTS. Piperidine derivatives Piperidine is an organic compound known as a structure element within many pharmaceuticals. For example, paroxetine is one of the most famous antidepressants of the selective serotonin reuptake inhibitor

2. class, which is used to treat major depressive disorder, obsessive- compulsive disorder, social anxiety disorder, and posttraumatic stress disorder. Indole derivatives Indole is an aromatic heterocyclic compound with the basic formula C8H7N, which is widely distributed in the natural environment and can be produced by bacteria. And its derivative tryptophan is a precursor to the neurotransmitter serotonin and the hormone melatonin. Piperazine derivatives Piperazine consists of a six-membered ring with two nitrogen atoms at opposite positions in the ring, which was the first anthelmintic in 1953. Piperazine hydrate, piperazine adipate and piperazine citrate are the most common anthelmintic compounds according to the references. Amide derivatives Amide is known as an acid amide that is pervasive in the nature. Paracetamol is a typical drug for treating pain, fever, osteoarthritis, and headaches. Ether derivatives Ether is a class of organic compound that contains an oxygen atom connected to two alkyl or aryl groups. Ether is common in organic chemistry and even more prevalent in biochemistry. Diethyl ether is one of the important ethers formerly used as a general anesthetic. Ester derivatives An ester is a compound that one of the hydroxyl groups replaced by an alkoxy group. Glycerides and phosphoester are the main classes of lipids that making up of animal fats and the backbone of DNA molecules, respectively.

3. Amine derivatives Amines are a series of compounds with a nitrogen atom, and widely exist in organisms. Proteins, nucleic acids, hormones, antibiotics and many alkaloids are the derivatives of amines. Chlorpheniramine is an antihistamine from amides derivatives that helps to relieve allergic disorders. Alkane Derivatives Aldehyde derivatives Aldehydes are a group of organic compounds with formyl groups, wherein the carbonyl center is connected with a hydrogen atom and an R group. Alkyne derivatives An alkyne is an unsatured organic compound with carbon-carbon triple bond and occurs in some pharmaceuticals, including the contraceptive noretynodrel, the antiretroviral efavirenz and the antifungal terbinafine. Alkene derivatives Alkenes are usually recognized by the carbon-carbon double bonds presented in their chemical structure. Carboxylic acid derivatives Carboxylic acid is a class of organic compound in which a carbon atom is bonded to an oxygen atom and a hydroxyl group at the same time. Alcohol derivatives In chemistry, alcohols are any organic compounds with hydroxyl functional group bound to a saturated carbon atom. Ketone derivatives

4. Ketones are simple compounds that contain a carbonyl group and used as solvents, polymer precursors, and pharmaceuticals. Haloalkane derivatives A compound with one or more halogens is usually called haloalkane or halogenoalkane. Haloalkane is a most common starting material for synthesizing drug molecule. BOC Sciences is a reliable provider of HTS libraries. And we will offer you a complete appraisal report or certificate of compound’s purity and chemical structure. We are hoping to hear from you.