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ppia

This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin bindingprotein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008]

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ppia

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  1. ppia ppia Official Full Name Official Full Name peptidylprolyl isomerase A (cyclophilin A) Background Background This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding- protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008] Synonyms Synonyms PPIA; peptidylprolyl isomerase A (cyclophilin A); CYPA; CYPH; HEL-S- 69p; peptidyl-prolyl cis-trans isomerase A; PPIase A; rotamase A; cyclophilin; T cell cyclophilin; cyclosporin A-binding protein; epididymis secretory sperm binding protein Li 69p; Recombinant Recombinant Proteins Proteins  Cell & Tissue Lysates Cell & Tissue Lysates Product Product na name me Cat.# Cat.# Source (Host) Source (Host) Species Species Tag Tag Price Price Ppia-872M Recombinant Mouse Ppia Protein E.coli Mouse +Inquiry PPIA-1140H Recombinant Human PPIA, His tagged E. coli Human His +Inquiry

  2. Product Product na name me Cat.# Cat.# Source (Host) Source (Host) Species Species Tag Tag Price Price PPIA-187H Recombinant Human PPIA Mammalian Cells Human His +Inquiry PPIA-22H Recombinant Human PPIA protein, GST-tagged E. coli Human GST +Inquiry PPIA-26334TH Recombinant Human PPIA E. coli Human N/A +Inquiry PPIA-26337TH Recombinant Human PPIA Human +Inquiry PPIA-60H Recombinant Human PPIA, His-tagged E. coli Human His +Inquiry PPIA-8311H Recombinant Human PPIA, His tagged E. coli Human His +Inquiry PPIA-13179M Recombinant Mouse PPIA Protein Mammalian Cells Mouse His +Inquiry Ppia-871M Recombinant Mouse Ppia, His tagged E. coli Mouse His +Inquiry

  3. Product Product na name me Cat.# Cat.# Source (Host) Source (Host) Species Species Tag Tag Price Price PPIA-4600R Recombinant Rat PPIA Protein Mammalian Cells Rat His +Inquiry Ppia-5691R Recombinant Rat Ppia protein, His-tagged E. coli Rat His +Inquiry PPIA-3543R Recombinant Rhesus monkey PPIA Protein, His-tagged Mammalian Cells Rhesus Macaque His +Inquiry PPIA-5692R Recombinant Rhesus monkey PPIA protein, His-tagged E. coli Rhesus monkey His +Inquiry PPIA-4005C Recombinant Chicken PPIA Mammalian Cells Chicken His +Inquiry PPIA-5689C Recombinant Cattle PPIA protein, His-tagged E. coli Cattle His +Inquiry PPIA-5690P Recombinant Pig PPIA protein, His-tagged E. coli Pig His +Inquiry

  4. Involved Pathway PPIA involved in several pathways and played different roles in them. We selected most pathways PPIA participated on our site, such as APOBEC3G mediated resistance to HIV-1 infection, Assembly Of The HIV Virion, Basigin interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPIA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Name Pathway Related Protein Pathway Related Protein APOBEC3G mediated resistance to HIV-1 infection APOBEC3G; gag; PSIP1; PPIA; HMGA1; BANF1 Assembly Of The HIV Virion PPIA; NMT2; gag; VPS37A Basigin interactions ITGB1B.1; BSG; SLC7A8A; SLC16A8; SLC3A2A; SLC7A11; SLC3A2B; SLC16A1; NADL1.1; SLC7A10 Binding and entry of HIV virion PPIA; CCR5; gag Budding and maturation of HIV virion CHMP4B; VPS37A; CHMP4C; gag; PPIA; PDCD6IP Cell surface interactions at the vascular wall SLC7A6; BSG; SLC16A1; CEACAM6; DOK2; GRB7; FN1B; SLC7A8A; SLC3A2A; CD84 Disease WHSC2; OGN; TRAT1; OS9; HEY2; KPNA5; gag; RBP4; FMOD; SYT2 Early Phase of HIV Life Cycle gag; BANF1; CCR5; PSIP1; PPIA Protein Function PPIA has several biochemical functions, for example, peptide binding, peptidyl-prolyl cis-trans isomerase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPIA itself. We selected most functions PPIA had, and list some proteins which have the same functions with PPIA. You can find most of the proteins on our site. Function Function Related Protein Related Protein Function Function peptide binding Related Protein Related Protein RNPEPL1; NPFFR1L2; LTA4H; TPP1; PCSK5; CSNK1D; GNRHR1; CLTA; CCKAR; PLOD1 Function Function peptidyl-prolyl cis-trans isomerase activity

  5. Related Protein Related Protein PPIF; PPIL1; PPIAB; PPIAL4B; PPIAL4C; PPIL2; PPIG; PPID; FKBP10; FKBP4 Function Function poly(A) RNA binding Related Protein Related Protein ZFP622; ZFP598; COA6; EIF4A2; C14orf166; DDX6; RPS15; MRPS31; HIST1H4J; DDX51 Function Function protein binding Related Protein Related Protein LENG1; ITGA3; PVRL1; ZKSCAN1; TFRC; RPS18; YIPF3; TARSL2; TNNC2; TNP1 Function Function unfolded protein binding Related Protein Related Protein HSP90B1; CCT7; DNAJA3B; CCT6A; DNAJA2; SSUH2.2; DNAJA3; RUVBL2; AIPL1; ERLEC1 Function Function virion binding Related Protein Related Protein CLEC4M; HIPK2; HSP90B1; PTX3; APCS; CD209; PPIA; PVRL1; TSG101 Interacting Protein PPIA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPIA here. Most of them are supplied by our site. Hope this information will be useful for your research of PPIA. gag; q99ib8-pro_0000045602; LNX1; SUPT5H; PTPRN; AIFM1; gag-pol PPIA Related Articles Lacombe, J; Mange, A; et al. A Multiparametric Serum Marker Panel as a Complementary Test to Mammography for the Diagnosis of Node- Negative Early-Stage Breast Cancer and DCIS in Young Women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 23:1834-1842(2014). Garibo, D; Flores, C; et al. Inhibition equivalency factors for microcystin variants in recombinant and wild-type protein phosphatase 1 and 2A assays. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 21:10652-10660(2014).

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