Japan Radiotherapy Market Analysis

1. A sample report on Japan Radiotherapy Market Analysis

2. This report presents a strategic analysis of the Japan Radiotherapy Market and a forecast for its development in the medium and long term. It provides a comprehensive overview of the market value, dynamics, segmentation, main players, growth and demand drivers, challenges & future outlook, etc. This is one of the most comprehensive reports about the Japan Radiotherapy Market, and offers unmatched value, accuracy, and expert insights.

3. Report Scope Report Attribute Details Number of Pages 70-80 Base Year for Estimation 2022 Forecast Period 2023-2030 Market Overview, Revenue Forecast, Market Segmentation, Growth Factors and Trends, Competitive Landscape, Key Company Profiles, Government Policies, Regulatory Landscape, Reimbursement Scenario Report Coverage Quantitative Units Revenue in USD Million/Billion (Mn/Bn) Research Approach Secondary Research (80%), Primary Research (20%) Click on the icon to know the detailed methodology 3 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

4. Table of Content CONTENT PG. NO. 09-17 1. Market Overview 1.1. Market Overview: Global 1.2. Overview: Japan 1.3. Economic Overview: Japan 1.4. Statistics at a Glance: Japan 1.5. Digital Health in Japan 1.6. Healthcare Scenario in Japan 1.7. Health Insurance Coverage: Japan 18-23 2. Market Size and Forecasting 2.1. Market Size and Forecasts 2.2. Market Segmentation 2.2.1. By Technology 4 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

5. Table of Content CONTENT PG. NO. 2.2.2. By Application 2.2.3. By End User 24-28 3. Market Dynamics 3.1. Market Growth Drivers 3.1.1. Japan Radiotherapy Market Driver 1 3.1.2. Japan Radiotherapy Market Driver 2 3.1.3. Japan Radiotherapy Market Driver 3 3.2. Market Restraints 3.2.1. Japan Radiotherapy Market Restraint 1 3.2.2. Japan Radiotherapy Market Restraint 2 3.2.3. Japan Radiotherapy Market Restraint 3 29-36 4. Competitive Landscape 5 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

6. Table of Content CONTENT PG. NO. 4.1. Key Company Profile 4.1.1. Hitachi Ltd. 4.1.2. Toshiba Corporation 4.1.3. Mitsubishi Electric Corporation 4.1.4. IHI Corporation 4.1.5. Sumitomo Heavy Industries Ltd. 4.1.6. Shimadzu Corporation 4.1.7. Elekta K.K. 4.1.8. Hamamatsu Photonics K.K. 4.1.9. Osaka Heavy Ion Therapy Center 4.1.10. Varian Medical Systems 37-40 5. Regulatory & Reimbursement Scenario 6 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

7. Table of Content CONTENT PG. NO. 5.1. Regulatory Scenario 5.2. Reimbursement Regulation 7 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

8. Radiotherapy Radiotherapy, also known as radiation therapy, is a medical treatment that uses high doses of radiation to target and kill cancer cells. It is a crucial component in the management of various cancers and is employed with the goal of either curing the cancer, controlling its growth, or relieving symptoms ▪ Radiotherapy works by damaging the DNA inside the targeted cells, preventing them from dividing and, ultimately, leading to their destruction ▪ There are two primary types of radiotherapy: external beam and internal (brachytherapy) External Beam Radiotherapy: This is the more common form of radiotherapy. It involves directing a focused beam of radiation from outside the body onto the cancerous cells. The patient typically receives treatment on an outpatient basis, and the sessions are carefully planned to maximize the radiation's impact on the cancer while minimizing exposure to surrounding healthy tissues ▪ Internal Radiation Therapy: In this type of radiotherapy, radioactive sources are placed directly inside or very close to the tumor. This allows for a highly targeted dose of radiation to be delivered to the cancer cells while reducing exposure to nearby normal tissues. This therapy is commonly used in the treatment of prostate, breast, and gynecological cancers ▪

9. Japan Radiotherapy Market Analysis 1. Market Overview

10. 1.1 Market Overview: Global Scenario of Radiotherapy Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ 50% of all patients with cancer worldwide require radiotherapy <60% patients have access to radiotherapy in middle income countries In this section you will get an understanding of the topic, which includes the prevalence of the disease, the application of medical devices, new technology, and other details related to the topic ▪ 0.4 Mn Children develop cancer each year 10 Mn+ Deaths due to cancer, 1/3rd of which is due to tobacco consumption In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ 43.1% Is the market share ofNorth America in the world $6.9 Bn is the estimatedglobal market for radiotherapy for 2022 Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ Illustrative Illustrative 10 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

11. 1.1 Market Overview: Global Europe ~Revenue to reach $3.2 Bn by 2030 North America ~Market Size of $3.6 Bn APAC -Fastest CAGR Africa Japan ~Market Size of $xx Bn ~Market Size of $xx Bn Illustrative Illustrative 11 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

12. 1.2 Overview: Japan Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ In this section you will get an understanding of the demographics of the country/region, which includes the population, GDP, healthcare expenditure and other details related to the topic ▪ 125 Mn + Population of Japan in 2022 4.2 Tn Is the Gross Domestic Product (GDP) in Japan in 2022 In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ 49.1 Is the median age in Japan, in 2022 11.5% of Japan’s GDP is spent on health in 2022 12 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

13. 1.3 Economic Overview: Japan Population of Japan, (2020-2030) GDP of Japan, (2020-2030) XX XX XX XX 2020 2021 2022 2023F 2024F 2025F 2026F 2027F 2028F 2029F 2023F 2020 2021 2022 2023F 2024F 2025F 2026F 2027F 2028F 2029F 2023F Population Split (2023) In this section you will get an understanding of the demographics of the country/region, which includes the population, GDP, healthcare expenditure and other details related to the topic ▪ By Gender By Age Group In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ 0-14 15-24 25-54 55-64 65+ Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ Male 49% Female 51% Illustrative Illustrative 13 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

14. 1.4 Statistics at a Glance: Japan Japan Radiotherapy Market Statistics Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ 1 Mn+ newly diagnosed patients with cancer in the country per year 283,000 number of patients who received radiotherapy in 2019 In this section you will get an understanding of the topic, which includes the prevalence of the disease, the application of medical devices, new technology, and other details related to the topic in Japan ▪ In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ 50%-60% of patients with cancer needed radiotherapy as part of their cancer treatment <30% of patients with cancer had access to radiotherapy in Japan Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ 14 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

15. 1.5 Digital Health in Japan Japan Digital Health Market Forecast, 2022-2030 (in $Bn) 2022 2023F 2024F 2025F 2026F 2027F 2028F 2029F 2030F Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ In this section you will get an understanding of the overall Digital Health market in Japan, which includes the market size, current trends and other details related to the topic ▪ In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ Illustrative Illustrative 15 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

16. 1.6 Healthcare Scenario in Japan Healthcare scenario in Japan is characterized by a robust system that provides universal access to high-quality healthcare services Private Health Insurance Public Health Insurance ▪ Around X% of the total population in Japan ▪ National Health Insurance (NHI): Every Japanese citizen and resident (except short-term residents) can subscribe to NHI ▪Public health insurance covers most citizens/residents and the system pays 70% or more of medical and prescription drug costs with the remainder being covered by the patient ▪ Pricing is Cost of Healthcare System in Japan Japan public healthcare is funded by the ▪ Illustrative Illustrative 16 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

17. 1.7 Health Insurance Coverage: Japan % of People by Type of Health Insurance Coverage (2022) Number of People By Health Insurance Coverage Coverage Type 2020 2021 Change % 8.3 Uninsured Total 327,521 328,074 91.7 With health insurance Any health plan 299,230 300,887 0.4 Any private plan 217,896 216,366 –0.6 66.0 Any private plan Employment-based 178,737 178,285 –0.2 54.3 Employment-based Direct-purchase 33,869 33,555 –0.1 10.2 Direct-purchase Marketplace coverage 10,924 11,389 0.1 3.5 Marketplace TRICARE 9,165 8,299 –0.3 2.5 TRICARE Any public plan 112,925 117,095 1.2 58,541 60,226 0.5 35.7 Any public plan 18.4 Medicare 58,778 61,940 0.9 18.9 Medicaid VA and CHAMPVA 2,967 3,151 0.1 1.0 VA and CHAMPVA Uninsured 28,291 27,187 –0.4 In 2022, most people (98.3%) had health insurance coverage at some point during 2022 and 1.7 % of people were uninsured for the entire calendar year More people had private health insurance (66%) than public coverage (35.7%) Employer-based insurance was the most common subtype of health insurance in the civilian, noninstitutionalized population (54.3%), followed by Public (18.4%), direct-purchase insurance (10.2%), TRICARE (2.5%), and VA and CHAMPVA health care (1%) ▪ ▪ ▪ Illustrative Illustrative 17 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

18. Japan Radiotherapy Market Analysis 2. Market Size and Forecasting

19. 2.1 Market Size and Forecasts Japan Radiotherapy Market Forecast, 2022-2030 (in $Bn) Click on the icon to know the methodology and assumption XX Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ XX In this section you will get an understanding of the overall market, which includes the market size, current trends and other details related to the topic ▪ 2022 2023F 2024F 2025F 2026F 2027F 2028F 2029F 2030F In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ 2023 2024 2025 2026 2027 2028 2029 2030 Major Markets Patient ($Mn) 2.74 2.82 2.90 2.94 2.98 3.02 3.07 3.12 Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ Japan Patient Size ($Bn) 0.51 0.61 0.68 0.69 0.70 0.71 0.72 0.73 % of Patients 18.75% 21.70% 23.56% 23.45% 23.42% 23.39% 23.34% 23.45% Global Market Size ($Bn) 3,620 3,780 3,950 4,128 4,314 4,508 4,711 4,937 Japan Market Size ($Bn) 61 74 84 87 91 95 99 106 Illustrative Illustrative 19 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

20. 2.2 Snapshot of Radiotherapy Market Segmentation By Technology By Application By End User External Beam Radiation Therapy Lung Cancer Hospitals Internal Beam Radiation Therapy Prostate Radiotherapy Centers Colon Research Institutes Others Breast Others In this section you will get an understanding of the segmentations which will cover the Japan Radiotherapy Market ▪ In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Illustrative Illustrative 20 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

21. 2.2.1 Market Segmentation: By Technology External Beam Radiation Therapy in Japan is a significant component of the overall Market ▪ Japan Radiotherapy Market Share, By Technology (2022) Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ Others In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ External Beam Radiation Therapy Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic ▪ Internal Beam Radiation Therapy Illustrative Illustrative 21 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

22. 2.2.2 Market Segmentation: By Application Lung Cancer applications dominate the market compared to other segments with a substantial xx% ▪ Japan Radiotherapy Market Share, By Application (2022) Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ Others Lung Cancer In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic ▪ Prostate Cancer Breast Cancer Colon Cancer Illustrative Illustrative 22 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

23. 2.2.3 Market Segmentation: By End User Hospitals in Japan are a significant contributor to the overall Market ▪ Japan Radiotherapy Market Share, By End User (2022) Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ Research Institutes In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic ▪ Hospitals Radiotherapy Centers Illustrative Illustrative 23 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

24. Japan Radiotherapy Market Analysis 3. Market Dynamics

25. 3.1 Market Growth Drivers 3.1.1 By 2050, cancer prevalence in Japan is projected to reach 3,665,900 (3,210,200 to 4,201,400) thousand cases, representing a 13.1% increase from 2020 Shifts in dietary patterns, alterations in cigarette consumption, changes in the age of marriage, variations in the number of births, and advancements in cancer screening, diagnosis, and treatment collectively account for the observed changes in cancer prevalence ▪ Prevalence of various Cancers Brain, central… Gallbladder Ovary Lip, oral cavity Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ Cervix uteri Leukaemia Corpus uteri Thyroid In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Kidney Oesophagus Non-Hodgkin… Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ Bladder Pancreas Liver Rectum Breast Colon Prostate Stomach Lung Illustrative Illustrative 25 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

26. 3.1 Market Growth Drivers (continued) 3.1.2 Continuous advancements in radiotherapy technologies, coupled with substantial capital investment Ranked as the 3rd largest market globally for radiation oncology, Japan is home to the National Cancer Center Hospital, a prominent national cancer treatment facility with a rich history of delivering patient care for over six decades ▪ Top Technology & Investment Type Investment Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ XX 30.1% In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ YY 23.4% Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ ZZ 13.5% Illustrative Illustrative 26 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

27. 3.1 Market Growth Drivers (continued) 3.1.3 Collaborative efforts between public and private entities, combined with substantial funding for clinical trials Organizations such as the National Institutes for Quantum and Radiological Science and Technology (QST) and the National Institute of Radiological Sciences (NIRS) have played a pivotal role in advancing heavy ion radiotherapy using carbon ions. ▪ Clinical Trials Participation in Japan such collaborative approach not only facilitates crucial clinical trials but also accelerates the development and adoption of novel radiotherapy techniques, positioning Japan as a leader in cancer diagnosis and treatment ▪ In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ 2010 2022 2030 Illustrative Illustrative 27 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

28. 3.2 Market Restraints 3.2.1 Limited Access to Advanced Radiotherapy Technologies 3.2.2 Workforce Shortages and Training Gaps 3.2.3 Regulatory Challenges and Compliance Burdens Access to advanced radiotherapy technologies may be constrained by factors such as high initial costs, limited infrastructure, and regional disparities in healthcare resources A shortage of skilled professionals in the field of radiotherapy, including oncologists and radiography professionals, poses a significant restraint. The demand for radiotherapy services may outpace the availability of trained personnel, leading to challenges in delivering timely and quality treatments Stringent regulations may pose challenges for market players in terms of product approvals, certifications, and adherence to evolving standards, potentially slowing down the introduction of new technologies and treatments ▪ ▪ ▪ This limitation can impede the widespread adoption of cutting- edge radiotherapy modalities, restricting patient access to the latest and most effective treatments In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ ▪ In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ In order to obtain access to all of the information that you are seeking, you will need to purchase the final report Our analysis will thoroughly investigate the key restraints that may significantly impact business operations and growth. ▪ Illustrative Illustrative 28 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

29. Japan Radiotherapy Market Analysis 4. Competitive Landscape

30. 4.1 Key Company Profile Key Note: Here is the list of top 10 companies which will be covered in the final report ▪ Shimadzu Corporation 1 6 Hitachi Ltd. Each company will have slides for ▪ Overview Key details Offerings Name of products Recent activities/ Press Coverage Distribution and Vendor Partners Mergers, Acquisitions and Collaboration Financials (As per availability) If there are specific companies that you would like to be included in the report, please let us know via email In order to obtain access to all of the information that you are seeking, you will need to purchase the final report Illustrative Illustrative o o 2 7 Elekta K.K. Toshiba Corporation o o o Mitsubishi Electric Corporation Hamamatsu Photonics K.K. 3 8 o o Osaka Heavy Ion Therapy Center o 4 9 IHI Corporation ▪ Sumitomo Heavy Industries Ltd. Varian Medical Systems ▪ 10 5 30 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

31. 4.1.1 Hitachi Ltd. Founded: 1910 Hitachi Ltd. is involved in healthcare through its innovative technologies and systems/solutions. They deliver digital technology and innovation for implementing healthcare services tailored to individuals ▪ Global HQ: Tokyo, JP Hitachi Ltd. specializes in a wide range of products and solutions, including digital systems, power and renewable energy solutions, railway systems, and healthcare products Revenue: $ 60.53 Bn Hitachi's healthcare solutions include radiation therapy for improving the quality of life in cancer treatment and in-vitro diagnosis ▪ No. of Employees: 368,247 A significant portion of its revenue generated from international markets, particularly Asia, Europe, and North America ▪ Locations: 150+ Website: hitachi.com Recent Activity/ Press Coverage Key Financials 36.2% $72.1 80.0 37.0% Oct, 2023: Hitachi Asia Ltd. has announced the successful delivery of a proton therapy system to the National Cancer Centre Singapore. This marks Hitachi's inaugural proton therapy system to commence operations in Southeast Asia ▪ 70.0 36.0% $60.9 $61.6 60.0 35.0% 50.0 34.0% 32.6% 31.4% 40.0 33.0% 30.0 32.0% May, 2022: Hitachi High-Tech Corporation, in a strategic move, has initiated a partnership with Invivoscribe, Inc., a leading global provider of blood cancer testing kits and services. The Partnership aims to accelerate the molecular diagnostics and precision medicine businesses of both companies ▪ 20.0 31.0% $4.7 $3.6 $0.9 10.0 30.0% 0.0 29.0% 2020 2021 2022 Revenue ($ Bn) Net Income ($ Bn) Gross Profit margin 31 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

32. 4.1.1 Hitachi Ltd. (continued) Partnerships Ecosystem Partnerships Ecosystem Major Distribution Partners GE Healthcare is a leading provider of medical imaging and information technology solutions &partners with IBM Watson to offer AI-powered solutions for cancer diagnosis, and patientmonitoring. Philips Healthcare is a leading provider of healthcare technology solutions and partners with IBM Watson to offer AI-powered solutions for patient engagement,and remotemonitoring. Siemens Healthineers is a leading provider of medical imaging and information technology solutions and partners with IBM Watson to offer AI-powered solutions for cancer diagnosis, treatmentplanning, and patient monitoring. Cerner is a leading provider of electronic health records (EHR) and healthcare information technologysolutions. Epic Systems is a leading provider of EHR and healthcare information technology solutions. Illustrative Illustrative 32 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

33. 4.1.1 Hitachi Ltd. (continued) Revenues ($Bn), 2020-2030 Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ In this section you will the understating of financial overview of the company, which includes revenue forecasting, segment revenue and other key details as per availability ▪ 2020 2021 2022 2023F 2024F 2025F 2026F 2027F 2028F 2029F 2030F In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Breakdown of Net Revenue by Segment, 2022 Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ 1 2 3 4 Illustrative Illustrative 33 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

34. 4.1.2 Company 2 Founded: Global HQ: Revenue: No. of Employees: Locations: Website: Recent Activity/ Press Coverage Key Financials 56.1% 120.0 57.0% $104.8 $96.7 56.0% $93.5 53.2% 100.0 55.0% 54.0% 80.0 53.0% 49.8% 52.0% 60.0 51.0% 50.0% 40.0 49.0% $19.1 $13.8 $10.7 48.0% 20.0 47.0% 0.0 46.0% 2020 2021 2022 Revenue ($ Bn) Net Income ($ Bn) Gross Profit margin Illustrative Illustrative Sources: 34 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

35. 4.1.2 Company 2 (continued) Partnerships Ecosystem Major Distribution Partners Major Vendor Partners Illustrative Illustrative 35 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

36. 4.1.2 Company 2 (continued) Revenues ($Bn), 2020-2030 Please be aware that this sample report is intended to provide you with a brief overview of the kind of information and analysis that will be presented in the final report ▪ xx xx xx In this section you will the understating of financial overview of the company, which includes revenue forecasting, segment revenue and other key details as per availability ▪ 2020 2021 2022 2023F 2024F 2025F 2026F 2027F 2028F 2029F 2030F In order to obtain access to all of the information that you are seeking, you will need to purchase the final report ▪ Breakdown of Net Revenue by Segment, 2022 Final report will be comprehensive and detailed, and it will include data, analysis, trends, and other relevant information related to the topic or subject matter of interest ▪ 1 2 3 4 Illustrative Illustrative 36 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

37. Japan Radiotherapy Market Analysis 5. Regulatory & Reimbursement Scenario

38. 5.1 Regulatory Scenario Pharmaceuticals and Medical Devices Agency (PMDA) The PMDA is a regulatory agency responsible for ensuring the safety, efficacy, and quality of pharmaceuticals and ▪ medical devices in Japan It reviews and approves applications for marketing authorization, including those related to radiotherapy equipment, ▪ ensuring compliance with Japanese regulatory standards Ministry of Health, Labour and Welfare (MHLW) The MHLW oversees health-related policies in Japan and plays a crucial role in the regulation and supervision of medical ▪ devices, including radiotherapy equipment It works in conjunction with the PMDA to establish and enforce regulatory standards, guidelines, and protocols for the ▪ safe and effective use of radiotherapy technologies Illustrative Illustrative Illustrative 38 38 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

39. 5.2 Reimbursement Regulation Government provide health insurance coverage for more than 4 in 10 Population In Japan, the reimbursement and regulation of radiotherapy involve a combination of public and private entities. Public Insurance: Public reimbursement for healthcare services in Japan is primarily managed through the national health insurance system, overseen by the Ministry of Health, Labour and Welfare (MHLW). The government determines reimbursement rates within this universal healthcare framework. The national health insurance system ensures broad access to medical treatments, including radiotherapy, and the MHLW plays a central role in establishing reimbursement policies and rates o OtherPublic 1% OtherPrivate 3% Uninsured 9% o Public Insurance 38% Private Insurance: o Private reimbursement for healthcare services in Japan involves collaboration between private insurance companies and healthcare providers. Insurance companies negotiate and determine reimbursement rates for services covered under private insurance plans o Private healthcare providers, such as hospitals and clinics, play a crucial role Employer-Sponsored 49% Health Insurance Coverage,2022 Illustrative Illustrative Illustrative 39 39 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

40. 5.2 Reimbursement Regulation (continued) Coverage Penetration (% Total Population) Source of Funding Spend on Healthcare (%of Current Health Expenditure) Government Expenditure Public Healthcare Coverage Private Health Insurance Out of Pocket Private Coverage Other NA NA 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023  Public healthcare coverage is provided by the government and includes programs like Public and Private  Public is a federal program that provides healthcare coverage to individuals who are 65 years of age or older, as well as certain younger people with disabilities  Private is a joint federal-state program that provides healthcare coverage to individuals with low income and limited resources 6.3% 4.08% 5.1% 3.8% 2.2% 2.4% 3.6% GDP Growth (yoy) 14.7% 11.3% 15.5% 7.5% 4.2% NA NA HC Spend Growth (yoy) Reimbursement Market Trends ▪ Shift towards value-based care has been a significant trend in the US healthcare system, with payers and providers increasingly focused on improving patient outcomes and reducing costs ▪ This has led to the development of alternative payment models such as accountable care organizations (ACOs) and bundled payment arrangements, which incentivize providers to deliver high-quality, cost-effective care Illustrative Illustrative 40 A Sample Report on Japan Radiotherapy Market Analysis I Confidential

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