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Dr. MYTHREYI RAJENDRAN www.milirskinclinic.com
Platelet Rich Plasma (PRP) in Dermatology An overview of Platelet Rich Plasma (PRP) in Dermatology, including its definition, history, and benefits.
Definition of PRP - PRP is a biological product with a concentration of multiple growth factors, chemokines, and plasma proteins. - It is defined as a portion of the plasma fraction of autologous blood with a platelet concentration above the baseline. - PRP is also known as "liquid gold".
History of PRP - Hematologists created the term "PRP" in the 1970s to describe plasma with a higher platelet count. - Initially used as a transfusion product to treat thrombocytopenia. - Subsequently used in maxillofacial surgery and sports injuries. - More recently, interest in PRP in Dermatology has increased.
Platelets and Growth Factors - Platelets develop in the Bone marrow and contain Seceretory granules crucial to their function. - Each platelet contains approximately 50 – 80 granules. - PRP is a natural source of signaling molecules, including growth factors and cytokines. - Upon activation of platelets, the granules release growth factors and cytokines that modify the cellular environment.
Benefits of PRP in Dermatology - Promotes hair growth and stimulates new hair follicle development. - Used as a therapeutic tool for both androgenetic alopecia and alopecia areata. - Treats skin defects, such as acne scars and fine lines. - Enhances skin rejuvenation, promoting a more youthful appearance.
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