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    1. ????????? ?. ????? ???????

    2. ???? ???????

    3. ????? ????????? ??????? ?????? ????????? ?? ???????? ?????? ?????? ??????? ?????? ????????? ???????? ?? ????? ???????? ???? ??????? ???? ?????? ??????? ????? ?? ????? ??????? ?? ????? ????? ?? ??? ????? ?? ????????

    4. ????? ????????? ??????? ?????? ????????? ??? ????????? ????? ?? ????? ???????? ??????? ???? ??????? ??????? ???????? ????? ??????? ???????? Cofactor ??????? ???????? : ???? ??? ??? ????? ??? ?????????? Mg ??????? Fe ?????? ?? ???? ???? ?????? ????? ????? ???? ??????? ??????? Coenzyme ? ?????? ??? ????????? ?????? ? ???? ??????? . ???????? ??????? ????????? ??????? ??????? .

    5. ????? ????????? ??????? ?????? ????????? ??????? ???????? ??? ?????? ??????? ???????? ???? ?? ??????? ???? ???? ????? ??? ???????? ????????. ???? ??????? ???????? ????? ??? ??????? ????? ????? ????? ????????? ??????? ????????

    6. ????? ????????? ??????? ?????? ????????? ??? ????????? ????? ?????? ???????? ? ???? ??? ????? ????????? ?????????? ???? ??? ?????? ???? ? ??? ?? ?????? ???? ?????? ????? ?? ????? 1000 ?? ????????? ???????? ???? ????? ????? ?? ?????? ??? ???? ???? ?? ?????? ?????? ????? ?????? ?????

    7. ????? ????????? ??????? ?????? ????????? ???? ????????? ???? ???? ?????? ??????? ??? ????? Intracellular  ?? ???? ???? ???? ??????? ????? extracellular ??? ??????? ????? ???? ???? ????????? ?? ??????? ???? ?????? ???? ????? ?????? ???? ??????? ????? ???? ????? ???? ??? ?? ????? ??????? ???? ???? ?? ????????? ?????? ??? ??????? ??????? ??? ???? ?????? ??????

    8. ????? ????????? ??????? ?????? ????????? ????? ??????? ??? ???? ???? Active site ????? ????? ? ?????? ???? ???? ???? ??????? ?????? ? ???? ????? ????? ???????? ? ????? ?????? ???? ???? ????? ??????? ?????? ?????? Substrate

    9. ????? ????????? ??? ???????? ??? ??? ????? ????????? ???? ??? ???? ????? ??? ??? ??? ????? ??????? ?? ???? ??? ??????? ??????. ??? ???? ??? ???? ????? ???? ????? ?????? ??? ????????? ???????? ?? ???? ????? ???? ?????? ?? ????? ???????? ??????? ?????? ???? ????? ?? ????? ??? 1961. ????? ?????? ???? ????? ????????? ?? ????? ??????? substrates ???? ???? ????????? ???? ????? ???????? ase? ????? ??? ??????? ???? ???? ?????? ??????? ?????? ????????? amylase? ???????? ???? ???? ?????? ?????? ??????? ?????? ??????? lipase ???????? ???? ???? ?????????? ??????? ?????? ????????? protease.

    10. ????? ????????? ??? ???????? ??? ??? 1961 ?????? ????????? ??? ????? ?????? ??? ?? ???? ?????? ??????? ?????? ??????? ??????? ??????? ?????? ???????: ?????? ????? ??? ??????? ?????????? ???????. ?????? ?????? ??? ??????? ?????????? ??????? ???? ???? ???? ???????. ?????? ?????? ??? ??? ??????? ???? ??? ?????? ??????? ????? ??? ?????? ????? ?? ????? ?????????.

    11. ????? ????????? ????? ???? ????????? ?? ??? ????? ?????? ??: 1? ????????? ??????? ? ????????  oxidoreductases ???? ???????? ????? ?????? ?? ????? ???????? ?? ??????? 2? ????????? ??????? (??? ???????? ???????)  transferases ???? ???????? ??????? ??? ??? ?????? ?????????? ?? ?????? ????? ??????? 3?) ????????? ???????) ????????? ???? ???? ??????? ?????? hydrolases ???? ?????? ????? ??????? ?????? ???? ??? ??? ????? ???????? ??? ??????? ?????? ?? ???????

    12. ????? ????????? 4? ????????? ??????? lyases ??? ????????? ??????? ??????? C-O 5? ??????? ??????? ?? ??????? ?? ????????? ???????? isomerases ??????? ???? ??? ??????? 6? ????????? ?????????? ?? ????????? ??????? ligases ??? ???? ??????? ?? ??? C-C C-O C-N ???? ?? ??? ??? ????? ??????

    13. ??????? Catalysis ??????? ????? ???? ??? ?? ???????? ???? ???? ???? ????? ???? ?? ??? ????? ???? ??????? ????????? . ????? ?????? ?????? ( ???? ????? ) ???? ?????? ???? ????? ??? ????? ???? ??????? ??? ?? ???? ??? ???? ???????

    14. ??????? Catalysis ????? ???????? ???????: ????? ???? ??????? ????? ???? ????? ???? ??? ????? ???? ??????? ????????? ???????? ?? ???? ??????? ??????? ????? ???????

    15. ??????? Catalysis ????? ???????? ?????? ?????: ??? ????? ??????? ???? ? ?? ??????? ????????? ??? ???? ?????? ????? ????? ???????? ?????? ????????: ??? ?????? ?????? ???? ?? ???? ??????, ?????, ????? ?? ?? ?????? ???? ???? ?????? ?? ????????? ?? ????? ????????

    16. ??????? Catalysis

    17. ??????? Catalysis

    18. ?????? ?????? ?????? ??????? ????????? ???? ??????? ??? ???? ???? ????? ???? ????? ??? ???? ??? ?? ???? ???? ??? ?? ???? ????? ??????? ??????? ? ??? ????? ???? ??????? ??? ???? ???? ????? ??? ?????? ????? ??? ????? ??????? ?????? ??? ???????? ?????? ?????? ?????? ?????? ???? ?? ???????? ???????? ????? ?????????? ? ???? ?????? .

    19. ?????? ?????? ???????? ??? ??????? ??? ????? ????? ??? ?????, ????? ?? ???? ?? ?? ????? ???? ???? ?? ???? ????? ?? ???? ??????? ????? ??? ?????? ?????? ?????? ??? ?? ??? ???? ?????? (substrate) ???? ???? ????? ??????? , ??? ????? ?????? ?????? ?? ??? ?????? . ???????? ????? ???? ?????? ???????? ?????? ????? "?????" ????? (Enzyme-Substrate Complex). ?? ????? ?????? ?????? ?????? ????? ????? ?????? ??????? :

    20. ?????? ?????? ?????? ??????? ?????????

    21. ?????? ?????? ?????? ??????? ????????? ???? ???????? ?? ??????? ????? ??? ????? ???? ?? ????? ??? ????? ???? ?? ????? ???? ??? ??????? ??? ????? ? ???? ?? ???? ??? ?? ?????? ????? ??? ?????? ???????? ??????? ?? ???? ??????? ???????? ????? ????????? ???? ?????? ???????

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