Metrogyl 400: Uses, Dosage, Side Effects, and More

1. What is Metrogyl 400? Metrogyl 400 is an antibiotic and antiprotozoal medication used to treat various infections caused by bacteria and parasites. It contains metronidazole, which works by stopping the growth of bacteria and parasites. It is commonly used to treat infections of the skin, stomach, brain, and respiratory tract. by Lyfe chemist

2. How does Metrogyl 400 work? 1 2 3 Mode of Action Antibacterial and Antiprotozoal Properties Selective Toxicity Metrogyl 400 works by interfering with the DNA of bacteria and parasites, leading to their death and elimination from the body. It selectively targets the infectious organisms while leaving the body's own cells unharmed, minimizing side effects. It targets both bacteria and parasites, making it effective against a wide range of infections.

3. Indications for Metrogyl 400 Bacterial Infections Protozoal Infections Metrogyl 400 is indicated for the treatment of bacterial infections such as skin infections, bone and joint infections, and respiratory tract infections. It is also used to treat protozoal infections including amoebiasis, giardiasis, and trichomoniasis. Adjunct to Other Medications It may be prescribed in combination with other antibiotics or medications for certain severe infections.

4. Dosage and administration 200 mg 400 mg Initial Dose Specific Conditions The typical adult dose for bacterial infections is 500 mg to 2 g daily in divided doses for 7 to 10 days. For amoebic liver abscess treatment, the recommended dose is 400 to 800 mg three times a day for 5 to 10 days.

5. Possible side effects Common Side Effects Less Common Side Effects Allergic Reactions These may include nausea, headache, loss of appetite, and metallic taste in the mouth. If you experience a severe allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek immediate medical attention. Rare side effects may include seizures, severe dizziness, and mood changes.

6. Precautions and warnings Alcohol Avoidance Neurological Effects Pregnancy and Lactation Patients should avoid consuming alcohol during and at least one day after the completion of Metrogyl 400 treatment. There have been reports of neurological side effects, so caution is advised in patients with a history of seizures or neurological disorders. It should be used with caution in pregnant and breastfeeding women, and only if clearly needed under medical supervision.

7. Drug interactions Metrogyl 400 + Warfarin It may increase the anticoagulant effect of warfarin, leading to an increased risk of bleeding. Metrogyl 400 + Lithium It may increase the risk of lithium toxicity; close monitoring is necessary.

8. Conclusion Metrogyl 400 is a valuable medication for the treatment of various infections, providing a broad spectrum of activity against bacteria and parasites. Understanding its proper use, potential side effects, and interactions is crucial for safe and effective therapy.