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Enzyme Inhibition

Enzyme Inhibition. Inhibition:. Certain chemicals prevent enzymes from working. Role of Bond Strength. Strong Bond :Irreversible Inhibition Weak Bond: Reversible. Competitive: Works on active site. Non-competitive: Influences enzyme away from active site. Types of Inhibition.

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Enzyme Inhibition

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  1. Enzyme Inhibition

  2. Inhibition: • Certain chemicals prevent enzymes from working

  3. Role of Bond Strength • Strong Bond :Irreversible Inhibition • Weak Bond: Reversible

  4. Competitive: Works on active site Non-competitive: Influences enzyme away from active site Types of Inhibition

  5. Think-Pair-Share • Use your “mini-whiteboard” to draw how an enzyme interacts with a competitive and non-competitive inhibitor

  6. Special Class of non-Competitive • Allosteric Enzymes -Always quaternary structure -Specific receptor sites -Each subunit with own active site -Binds activators or inhibitors

  7. Feedback Inhibition

  8. 2 Part Foldable • Competitive vs. Non-Competitive Enzymes • Include: -Definition -Diagram -Graph (reaction rate vs. enzyme concentration) -Examples

  9. Jello Lab… • Independent Variable? • Dependent Variable? • Control? • Apparatus/Set-Up • Step-By-Step Procedure **This info is your ticket for doing the lab tomorrow!

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