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  1. 1. A team of researchers at a pesticide company are working produce a new rodent poison to address a growing problem of rat infestations at an old waterfront warehouse. The researchers are developing a poison that will cause the junctions between intestinal cells to break down. The poison will be incorporated into grain and left where the rodents will feed on it. Which of the following describes the most likely effect of this poison? A. The gap junctions will break down resulting in leaks in the digestive tract.B. The tight junctions will break down resulting in leaks in the digestive tract.C. The gap junctions will break down and interfere with absorption of nutrients.D. The tight junctions will break down and interfere with absorption of nutrients. 2. You have identified a novel cytoplasmic protein. Sequence analysis revealed the presence of a number of serine/threonine phosphorylation target motifs. Based on this data, you hypothesize that this protein may be a substrate for a A. protein kinase.B. receptor tyrosine kinase.C. G-protein-coupled receptor.D. phosphotyrosine adapter protein.

  2. Which of the following would NOT be found in a typical meiosis? (color indicates a homologous chromosome pair) A. B. E. C. D.

  3. A homozygous (A/A) mouse with brown eyes is crossed to a homozygous (a/a) mouse with blue eyes. The resulting A/a mice are mated to each other. What would be the fraction of these offspring that would have blue eyes? ½ 1/3 ¼ 1/8 1/16 2. A homozygous (A/A) mouse with brown eyes is crossed to a homozygous (aa) mouse with blue eyes. A resulting A/a mouse is mated to an a/a, blue-eyed mouse. What would be the fraction of these offspring that would have blue eyes? ½ 1/3 ¼ 1/8 1/16

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