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Table of Content - Global Phosphoramidite Market

The global phosphoramidite market is projected to reach $2,062.9 million by 2032 from $900.3 million in 2021, at a CAGR of 7.78% during the forecast period 2022-2032.

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Table of Content - Global Phosphoramidite Market

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  1. res Phosphoramidite Market - A Global and Country Level Analysis Table of Content GLOBAL PHOSPHORAMIDITE MARKET Focus on Type, End User, and Region Analysis and Forecast: 2022-2032 September 2022 All rights reserved at BIS Research Inc. 1

  2. BIS Research is a leading market intelligence and technology research company. BIS Research publishes in- depth market intelligence reports focusing on the market estimations, technology analysis, emerging high- growth applications, deeply segmented granular country-level market data and other important market parameters useful in the strategic decision making for senior management. BIS Research provides multi-client reports, company profiles, databases, and custom research services. GLOBAL PHOSPHORAMIDITE MARKET Copyright © 2022 BIS Research Inc. All Rights Reserved. This document contains highly confidential information and is the sole property of BIS Research. Disclosing, copying, circulating, quoting, or otherwise reproducing any or all contents of this document is strictly prohibited. Access to this information is provided exclusively for the benefit of the people or organization concerned. It may not be accessed by or offered whether for sale or otherwise to any third party. All rights reserved at BIS Research Inc. 2

  3. Table of Content Executive Summary .......................................................................... 15 1.Market ....................................................................................... 19 1.1 Product Definition ............................................................................................ 20 1.2 Inclusion and Exclusion .................................................................................. 20 2.Market Scope ............................................................................ 21 2.1 Key Questions Answered in the Report......................................................... 22 3.Research Methodology .............................................................. 23 3.1 Data Sources .................................................................................................... 24 3.1.1Primary Data Source ................................................................................... 24 3.1.2Secondary Data Sources ............................................................................ 25 3.2 Market Estimation Model ................................................................................. 25 3.3 Criteria for Company Profiling ........................................................................ 27 4.Market Overview ........................................................................ 28 4.1 Introduction ...................................................................................................... 28 4.2 Phosphoramidite Synthesis Process ............................................................. 29 4.2.1Stability Considerations for Phosphoramidite ......................................... 30 4.3 Applications of Phosphoramidite Chemistry ................................................ 31 4.4 Future Trends in Phosphoramidite Industry ................................................. 32 4.5 COVID-19 Impact on Phosphoramidite Industry ........................................... 33 GLOBAL PHOSPHORAMIDITE MARKET 4.6 Current Market Size and Growth Potential, $Million, 2022-2032 .................. 34 5.Industry Insights ........................................................................ 35 5.1 Overview ........................................................................................................... 35 5.2 Regulatory Considerations for Phosphoramidite ......................................... 35 5.2.1Challenges ................................................................................................... 35 5.2.2Current Regulatory Landscape .................................................................. 36 All rights reserved at BIS Research Inc. 3

  4. 5.2.3GMP, Control Strategy, and Facility Considerations ................................ 37 5.2.3.1 Brief Control Strategy ........................................................................................ 37 6.Market Dynamics ....................................................................... 39 6.1 Overview ........................................................................................................... 39 6.2 Impact Analysis ............................................................................................... 39 6.3 Market Drivers .................................................................................................. 40 6.3.1Increasing Synthetic Nucleotide Applications in Therapeutics .............. 40 6.3.2Growth in Synthetic Biology ...................................................................... 41 6.4 Market Restraints ............................................................................................. 41 6.4.1Challenges in Developing Long Nucleotide Sequences .......................... 41 6.4.2Competition from Emerging DNA Synthesis Technologies .................... 42 6.5 Market Opportunities ....................................................................................... 44 6.5.1Utilize advanced tools for lowering manufacturing cost and increasing production in gene synthesis .................................................. 44 7.Global Phosphoramidite Market, by Type, $Million, 2021-2032 ... 45 7.1 Overview ........................................................................................................... 46 7.2 DNA Phosphoramidites ................................................................................... 46 7.3 RNA Phosphoramidites ................................................................................... 48 7.4 Labeled Phosphoramidites ............................................................................. 50 7.5 Other Phosphoramidites ................................................................................. 51 8.Global Phosphoramidite Market, by End Users, $Million, 2021- GLOBAL PHOSPHORAMIDITE MARKET 2032 .......................................................................................... 52 8.1 Overview ........................................................................................................... 53 8.2 Pharmaceutical and Biotechnology Companies ........................................... 53 8.3 Diagnostic Laboratories .................................................................................. 55 8.4 Synthetic Biology and Research Institutes ................................................... 56 All rights reserved at BIS Research Inc. 4

  5. 9.Global Phosphoramidite Market, by Region, $Million, 2021- 2032 .......................................................................................... 57 9.1 Overview ........................................................................................................... 58 9.2 North America .................................................................................................. 59 9.2.1U.S. ............................................................................................................... 60 9.2.2Canada ......................................................................................................... 62 9.3 Europe .............................................................................................................. 63 9.3.1U.K. ............................................................................................................... 64 9.3.2Germany ....................................................................................................... 65 9.3.3France ........................................................................................................... 66 9.3.4Spain ............................................................................................................. 67 9.3.5Italy ............................................................................................................... 68 9.3.6Rest-of-Europe............................................................................................. 69 9.4 Asia-Pacific ...................................................................................................... 71 9.4.1Japan ............................................................................................................ 72 9.4.2China ............................................................................................................ 73 9.4.3India .............................................................................................................. 74 9.4.4Rest-of-Asia-Pacific ..................................................................................... 75 9.5 Rest-of-the-World ............................................................................................ 76 10.Competitive Insights .................................................................. 77 GLOBAL PHOSPHORAMIDITE MARKET 10.1Key Strategies and Development ................................................................... 77 10.1.1Overview ...................................................................................................... 77 10.1.2Business Expansions ................................................................................. 77 10.1.3Mergers and Acquisitions ........................................................................... 78 10.1.4Funding Activities ....................................................................................... 79 10.1.5Others ........................................................................................................... 79 10.2Market Share Analysis (by Company) 2021 ................................................... 80 All rights reserved at BIS Research Inc. 5

  6. 11.Market - Competitive Benchmarking & Company Profiles ........... 81 11.1Overview ........................................................................................................... 82 11.2Biosynth Carbosynth ...................................................................................... 83 11.2.1Company Overview ..................................................................................... 83 11.2.2Role of Biosynth Carbosynth in the Global Phosphoramidite Market ........................................................................................................... 83 11.2.3Key Competitors of the Company .............................................................. 83 11.2.4Corporate strategies ................................................................................... 84 11.2.4.1 Synergistic Activities .......................................................................................... 84 11.2.5Analyst Perspective .................................................................................... 84 11.3Bioneer Corporation ........................................................................................ 85 11.3.1Company Overview ..................................................................................... 85 11.3.2Role of Bioneer Corporation in the Global Phosphoramidite Market ........................................................................................................... 85 11.3.3Key Competitors of the Company .............................................................. 86 11.3.4Analyst Perspective .................................................................................... 86 11.4Lumiprobe Corporation ................................................................................... 87 11.4.1Company Overview ..................................................................................... 87 11.4.2Role of Lumiprobe Corporation in the Global Phosphoramidite Market ........................................................................................................... 87 11.4.3Key Competitors of the Company .............................................................. 87 GLOBAL PHOSPHORAMIDITE MARKET 11.4.4Analyst Perspective .................................................................................... 88 11.5QIAGEN N.V. ..................................................................................................... 89 11.5.1Company Overview ..................................................................................... 89 11.5.2Role of QIAGEN N.V. in the Global Phosphoramidite Market .................. 89 11.5.3Key Competitors of the Company .............................................................. 89 11.5.4Financials ..................................................................................................... 90 11.5.5Analyst Perspective .................................................................................... 92 All rights reserved at BIS Research Inc. 6

  7. 11.6Danaher Corporation (IDT) .............................................................................. 93 11.6.1Company Overview ..................................................................................... 93 11.6.2Role of Danaher Corporation (IDT) in the Global Phosphoramidite Market ........................................................................................................... 93 11.6.3Key Competitors of the Company .............................................................. 94 11.6.4Key Customers of the Company ................................................................ 94 11.6.5Financials ..................................................................................................... 94 11.6.6Analyst Perspective .................................................................................... 96 11.7TriLink BioTechnologies ................................................................................. 97 11.7.1Company Overview ..................................................................................... 97 11.7.2Role of TriLink BioTechnologies in the Global Phosphoramidite Market ........................................................................................................... 97 11.7.3Key Competitors of the Company .............................................................. 98 11.7.4Financials ..................................................................................................... 98 11.7.5Business Strategies .................................................................................. 100 11.7.6Analyst Perspective .................................................................................. 100 11.8Creative Biolabs ............................................................................................. 102 11.8.1Company Overview ................................................................................... 102 11.8.2Role of Creative Biolabs in the Global Phosphoramidite Market .......... 102 11.8.3Key Competitors of the Company ............................................................ 102 11.9PolyOrg, Inc. ................................................................................................... 103 GLOBAL PHOSPHORAMIDITE MARKET 11.9.1Company Overview ................................................................................... 103 11.9.2Role of PolyOrg, Inc. in the Global Phosphoramidite Market ................ 103 11.9.3Key Competitors of the Company ............................................................ 103 11.10Hongene Biotech Corporation ...................................................................... 104 11.10.1 Company Overview ............................................................................. 104 11.10.2 Role of Hongene Biotech Corporation in the Global Phosphoramidite Market ........................................................................... 104 All rights reserved at BIS Research Inc. 7

  8. 11.10.3 Key Competitors of the Company ..................................................... 105 11.10.4 Business Strategies ............................................................................ 105 11.11ChemGenes .................................................................................................... 106 11.11.1 Company Overview ............................................................................. 106 11.11.2 Role of ChemGenes in the Global Phosphoramidite Market ........... 106 11.11.3 Key Competitors of the Company ..................................................... 106 11.12BOC Sciences ................................................................................................ 107 11.12.1 Company Overview ............................................................................. 107 11.12.2 Role of BOC Sciences in the Global Phosphoramidite Market ....... 107 11.12.3 Key Competitors of the Company ..................................................... 108 11.12.4 Key Customers of the Company ........................................................ 108 11.13Tokyo Chemical Industry Co., Ltd. (TCI) ...................................................... 109 11.13.1 Company Overview ............................................................................. 109 11.13.2 Role of Tokyo Chemical Industry Co., Ltd. in the Global Phosphoramidite Market ........................................................................... 109 11.13.3 Key Competitors of the Company ..................................................... 110 11.14LGC Science Group Holdings Limited ......................................................... 111 11.14.1 Company Overview ............................................................................. 111 11.14.2 Role of LGC Science Group Holdings Limited in the Global Phosphoramidite Market ........................................................................... 111 11.14.3 Key Competitors of the Company ..................................................... 112 GLOBAL PHOSPHORAMIDITE MARKET 11.14.4 Key Customers of the Company ........................................................ 112 11.14.5 Financials ............................................................................................ 113 11.14.6 Business Strategies ............................................................................ 114 11.14.7 Analyst Perspective ............................................................................ 114 11.15AAT Bioquest, Inc. ......................................................................................... 115 11.15.1 Company Overview ............................................................................. 115 All rights reserved at BIS Research Inc. 8

  9. 11.15.2 Role of AAT Bioquest, Inc. in the Global Phosphoramidite Market ......................................................................................................... 115 11.15.3 Key Competitors of the Company ..................................................... 115 11.16Thermo Fisher Scientific, Inc. ....................................................................... 116 11.16.1 Company Overview ............................................................................. 116 11.16.2 Role of Thermo Fisher Scientific, Inc. in the Global Phosphoramidite Market ........................................................................... 116 11.16.3 Key Competitors of the Company ..................................................... 116 11.16.4 Financials ............................................................................................ 117 11.16.5 Analyst Perspective ............................................................................ 119 11.17Merck KGaA ................................................................................................... 120 11.17.1 Company Overview ............................................................................. 120 11.17.2 Role of Merck KGaA in the Global Phosphoramidite Market .......... 120 11.17.3 Key Competitors of the Company ..................................................... 120 11.17.4 Financials ............................................................................................ 121 11.17.5 Analyst Perspective ............................................................................ 123 GLOBAL PHOSPHORAMIDITE MARKET All rights reserved at BIS Research Inc. 9

  10. List of Figures Figure 1:Global Phosphoramidite Market Dynamics Figure 2:Global Phosphoramidite Market (by Type), $Million, 2021 and 2032 Figure 3:Global Phosphoramidite Market (by End User), $Million, 2021 and 2032 Figure 4:Global Phosphoramidite Market (by Region), $Million, 2021-2032 Figure 5:Global Phosphoramidite Market Segmentation Figure 6:Global Phosphoramidite Market Research Methodology Figure 7:Primary Research Methodology Figure 8:Volume-Based Market Sizing and Forecasting Methodology Figure 9:Structure of a Standard 2’-Deoxyadenosine Phosphoramidite Figure 10:Workflow of Phosphoramdite Synthesis Chemistry to Produce Oligonucleotides Figure 11:Phosphoramidite Synthesis Cycle Figure 12:Factors Impacting the Stability of Phosphoramidites Figure 13:Phosphoramidite Key Application Areas Figure 14:Global Phosphoramidite Market, $Million, 2021-2032 Figure 15:Challenges for Phosphoramidite as a Drug Product Figure 16:Control Strategy: Phosphoramidite Elements Figure 17:Elements of Microbial Control Strategy Figure 18:Details of GMP, Control Strategy, and Facility Considerations Figure 19:Market Dynamics Figure 20:Impact Analysis Figure 21:Factors Influencing Rise in Oligonucleotide Demand and Growing Market Figure 22:Breakthrough Achievements in Synthetic Biology, 2016-2020 Figure 23:Key Competitors Impacting Global Phosphoramidite Market Growth in Future Figure 24:Share of Global Phosphoramidite Market (by Type), $Million, 2021 and 2032 GLOBAL PHOSPHORAMIDITE MARKET Figure 25:Characteristics of DNA Phosphoramidites Figure 26:Global Phosphoramidite Market (DNA Phosphoramidites), $Million, 2021-2032 Figure 27:Global Phosphoramidite Market (RNA Phosphoramidites), $Million, 2021-2032 Figure 28:Global Phosphoramidite Market (Labeled Phosphoramidites), $Million, 2021-2032 Figure 29:Global Phosphoramidite Market (Other Phosphoramidites), $Million, 2021-2032 Figure 30:Share of Global Phosphoramidite Market (by End User), $Million, 2021 and 2032 Figure 31:Global Phosphoramidite Market (Pharmaceutical and Biotechnology Companies), $Million, 2021- 2032 Figure 32:Global Phosphoramidite Market (Diagnostic Laboratories), $Million, 2021-2032 All rights reserved at BIS Research Inc. 10

  11. Figure 33:Global Phosphoramidite Market (Synthetic Biology and Research Institutes), $Million, 2021-2032 Figure 34:Global Phosphoramidite Market (by Region), $Million, 2021-2032 Figure 35:Market Dynamics of North America Phosphoramidite Market Figure 36:North America Phosphoramidite Market, $Million, 2021-2032 Figure 37:Projections of the Older Adult Population in the U.S.: 2016 to 2060 (Million) Figure 38:U.S. Phosphoramidite Market, $Million, 2021-2032 Figure 39:Canada Phosphoramidite Market, $Million, 2021-2032 Figure 40:Market Dynamics of Europe Phosphoramidite Market Figure 41:Europe Phosphoramidite Market, $Million, 2021-2032 Figure 42:U.K. Phosphoramidite Market, $Million, 2021-2032 Figure 43:Germany Phosphoramidite Market, $Million, 2021-2032 Figure 44:France Phosphoramidite Market, $Million, 2021-2032 Figure 45:Spain Phosphoramidite Market, $Million, 2021-2032 Figure 46:Italy Phosphoramidite Market, $Million, 2021-2032 Figure 47:Rest-of-Europe Phosphoramidite Market, $Million, 2021-2032 Figure 48:Market Dynamics of the Asia-Pacific Phosphoramidite Market Figure 49:Asia-Pacific Phosphoramidite Market, $Million, 2021-2032 Figure 50:Japan Phosphoramidite Market, $Million, 2021-2032 Figure 51:China Phosphoramidite Market, $Million, 2021-2032 Figure 52:India Phosphoramidite Market, $Million, 2021-2032 Figure 53:Rest-of-APAC Phosphoramidite Market, $Million, 2021-2032 Figure 54:Rest-of-the-World Phosphoramidite Market, $Million, 2021-2032 Figure 55:Figure: Share of Key Developments, January 2019-August 2022 Figure 56:Business Expansions (by Company), January 2019-August 2022 Figure 57:Merger and Acquisition Activities (by Company), January 2019-August 2022 Figure 58:Market Share Analysis for the Global Phosphoramidite Market, 2021 GLOBAL PHOSPHORAMIDITE MARKET Figure 59:Total Number of Companies Profiled Figure 60:Bioneer Corporation’s Phosphoramidite Manufacturing Capacity Figure 61:Bioneer Corporation: Selective Product Portfolio Figure 62:Lumiprobe Corporation: Selective Product Portfolio Figure 63:QIAGEN N.V.: Selective Product Profile Figure 64:QIAGEN N.V.: Overall Financials, 2019-2021 Figure 65:QIAGEN N.V.: Revenue (by Segment), $Million, 2019-2021 Figure 66:QIAGEN N.V.: Revenue (by Region), $Million, 2019-2021 All rights reserved at BIS Research Inc. 11

  12. Figure 67:QIAGEN N.V.: R&D Expenditure, 2019-2021 Figure 68:Danaher Corporation (IDT): Selective Product Portfolio Figure 69:Danaher Corporation (IDT): Overall Financials, $Million, 2019-2021 Figure 70:Danaher Corporation (IDT): Revenue (by Segment), $Million, 2019-2021 Figure 71:Danaher Corporation (IDT): Revenue (by Region), $Million, 2019-2021 Figure 72:Danaher Corporation (IDT), R&D Expenditure, $Million, 2019-2021 Figure 73:TriLink BioTechnologies: Selective Product Portfolio Figure 74:Maravai LifeSciences Holdings, Inc.: Overall Financials, $Million, 2019-2021 Figure 75:Maravai LifeSciences Holdings, Inc.: Revenue (by Segment), $Million, 2019-2021 Figure 76:Maravai LifeSciences Holdings, Inc.: Revenue (by Region), $Million, 2019-2021 Figure 77:Maravai LifeSciences Holdings, Inc.: R&D Expenditure, $Million, 2019-2021 Figure 78:Creative Biolabs: Selective Product Portfolio Figure 79:PolyOrg, Inc.: Selective Product Portfolio Figure 80:Hongene Biotech Corporation: Selective Product Portfolio Figure 81:ChemGenes: Selective Product Portfolio Figure 82:BOC Sciences: Selective Product Portfolio Figure 83:Tokyo Chemical Industry Co., Ltd.: Selective Product Portfolio Figure 84:LGC Science Group Holdings Limited: Selective Product Portfolio Figure 85:LGC Science Group Holdings Limited: Overall Financials, $Million, 2019-2021 Figure 86:LGC Science Group Holdings Limited: Revenue (by Region), $Million, 2019-2021 Figure 87:AAT Bioquest, Inc.: Selective Product Portfolio Figure 88:Thermo Fisher Scientific, Inc.: Selective Product Portfolio Figure 89:Thermo Fisher Scientific, Inc.: Overall Financials, 2019-2021 Figure 90:Thermo Fisher Scientific, Inc.: Revenue (by Segment), $Million, 2019-2021 Figure 91:Thermo Fisher Scientific, Inc.: Revenue (by Region), $Million, 2019-2021 Figure 92:Thermo Fisher Scientific, Inc.: R&D Expenditure, $Million, 2019-2021 GLOBAL PHOSPHORAMIDITE MARKET Figure 93:Merck KGaA: Selective Product Portfolio Figure 94:Merck KGaA: Overall Financials, $Million, 2019-2021 Figure 95:Merck KGaA: Revenue (by Segment), $Million, 2019-2021 Figure 96:Merck KGaA: Revenue (by Region), $Million, 2019-2021 Figure 97:Merck KGaA: R&D Expenditure, $Million, 2019-2021 All rights reserved at BIS Research Inc. 12

  13. List of Tables Table 1: Companies and COVID-19 Impact Table 2: Guideline Summary for Phosphoramidites Table 3: Decreased Coupling Efficiency with Extending Oligonucleotide Sequence Table 4: Key Characteristics of Enzymatic-based and Phosphoramidite Synthesis Table 5: Examples of RNA Phosphoramidites Table 6: List of Approved Oligonucleotide-Based Therapies, 1998-2020 GLOBAL PHOSPHORAMIDITE MARKET All rights reserved at BIS Research Inc. 13

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