1 / 8

IP 3 R1

CaM-Seph. CaM-Seph. + Suramin. + Suramin. Seph. Seph. Input. A. IP 3 R1. B. EGTA. Ca 2+. IP 3 R1 1-225. EGTA. Ca 2+. A. P 49-81. B. P 106-128. a b c d e f g h. a b c d e f g h. EGTA. Ca 2+. 0. 12.5. 25. 37.5. 50. 75.

bliss
Download Presentation

IP 3 R1

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. CaM-Seph CaM-Seph + Suramin + Suramin Seph Seph Input A IP3R1 B EGTA Ca 2+ IP3R1 1-225 EGTA Ca 2+

  2. A P 49-81 B P 106-128 a b c d e f g h a b c d e f g h EGTA Ca2+ 0 12.5 25 37.5 50 75 100 0 12.5 25 37.5 50 75 100 [Suramin] (µM) [Suramin] (µM) C D

  3. 1499 1649 100 % 1-5-8-14 76 % IQ 60 % IQ 72% 1-5-8-14 A 1554-ldsqvnnlflkshnivqkta-1573 1554-ldsqvnnlflkshnivqktalnwrlsarnaar-1585 1564-kshnivqktalnwrlsarnaar-1585 1564-kshnivqktalnwrlsarnaarrdsvlaasrd-1595 (b) (c) (d) (e) B C a b c d e a b c d e Ca2+ EGTA D CaM P1554-1573 P1554-1585 P1564-1585 P1564-1595

  4. 0 12.5 25 50 75 100 [Suramin] (µM) A a b c d e f g EGTA Ca2+ B

  5. A Lvec L15 B C

  6. A B

More Related