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Organelles involved in synthesis and secretion of proteins. Examples of proteins:. hormones eg insulin. enzymes eg amylase. Transcription – mRNA copies DNA code. mRNA takes code through nuclear pore to ribosome. Translation –
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Organelles involved in synthesis and secretion of proteins Examples of proteins: • hormones eg insulin • enzymes eg amylase
Transcription – mRNA copies DNA code mRNA takes code through nuclear pore to ribosome Translation – on ribosomes - amino acids are assembled in the correct order using the code to make a protein
The rough endoplasmic reticulum transports the proteins through the cytoplasm and packages them in vesicles which pass to the Golgi apparatus
The Golgi apparatus receives vesicles containing protein from ER, modifies them (eg adds a carbohydrate group) and packages them into more vesicles to send to the cell surface membrane Virtual Cell movie Golgi apparatus Another animation
Fibroblasts showing actin & Golgi apparatus Cultured rat embryo fibroblasts scraped tosimulate wounding. After scraping the Golgireorient to the side of the cell nearest thewound. Filamentous actin is stained inred and the Golgi complex in green
Exocytosis – the vesicles containing finished protein fuse with the cell surface membrane and release their contents to the outside (secretion) Animation Constitutive secretion Regulated secretion
Put these in order! • secretory vesicle • Nucleus • Cell surface membrane • Ribosome (could be on ER) • Golgi • Nucleus • Ribosome (could be on ER) • Golgi • secretory vesicle • Cell surface membrane