1 / 6

A.C.T.H.

A.C.T.H. Adrenocorticotropic Hormone. Brittany Rupp. ACTH is produced from the anterior lobe of the pituitary gland. The target cells for ACTH are found in the adrenal cortex. A corticotropin -releasing hormone (CRH) from the hypothalamus causes ACTH to be produced. What about it?.

bono
Download Presentation

A.C.T.H.

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. A.C.T.H. Adrenocorticotropic Hormone Brittany Rupp

  2. ACTH is produced from the anterior lobe of the pituitary gland. • The target cells for ACTH are found in the adrenal cortex. • A corticotropin-releasing hormone (CRH) from the hypothalamus causes ACTH to be produced. What about it?

  3. ACTH is a polypeptide hormone that largely responds to stress. With this being the case, the release of it is more prominent during times of illness, injury, and disease. ACTH causes the release of cortisone, which allows you to handle stress. How does it work…

  4. In order to enter the target cell, CRH binds with the receptor protein, ACTH. By doing this the cell is informed to allow the protein to pass through. How does it enter?

  5. Too Little… Too Much… Cushing’s disease is a result of too much ACTH in the blood. • Addison’s disease occurs when there is loo little ACTH in the blood. Hyperpigmentation How much is enough? Since ACTH levels vary so much throughout the day, only skilled endocrinologist can determine safe levels.

  6. Addison’s Disease Cushing’s Disease Through surgery, along with radiation therapy, part of the pituitary gland can be removed to treat Cushing’s disease. Drugs such as Nizoral can be used to treat excess ACTH. • ACTH can be synthetically replaced to treat Addison’s disease. This is done so through cortisone hormone replacement tablets (Cortef) or corticosteroid injections. How to treat?

More Related