1 / 12

Fluconazole By

Fluconazole By. Latonya Miles 2 nd period Mr. Davis Botany Class. Classification. Availability. Pharmacokinetics. Fluconazole is almost completely absorbed within two hours.

carrie
Download Presentation

Fluconazole By

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. FluconazoleBy Latonya Miles 2nd period Mr. Davis Botany Class

  2. Classification

  3. Availability

  4. Pharmacokinetics • Fluconazole is almost completely absorbed within two hours. • The elimination half-life of fluconazole follows zero order kinetics and only 10% of elimination is due to metabolism. • Patients with impaired renal function will be at risk of overdose as well as patients taking drugs such as warfarin.

  5. Action/Therapeutic Effect

  6. Uses • Fluvonazole is an azole antifungal medication used to prevent and treat a variety of fungal and yeast infections.

  7. Administration • Single dose • The recommended dosage is 150 mg as a single oral dose. • Fluconazole may be administered either orally or by intravenous infusion. • Fluconazole injection has been used safely for up to 14 days of intravenous therapy.

  8. Indication • Fluconazole is indicated for the treatment and prophylaxis of fungal infections where other antifungal have failed or are not tolerated including: • Candidiasis- caused by susceptible strains of Candida • Tinea corporis • The drug may make you dizzy • Use caution engaging in activities requiring alertness such as driving or using machinery. • This medication should be used only when clearly needed during pregnancy.

  9. Precautions • Before you take Fluconazole you have to tell your doctor if you are allergic to it. • Do not use if the solution is cloudy or precipitated or if seal is not intact. • Parental drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

  10. Interactions(what causes increase damage when mixed with it) • Fluconazole is an inhibitor of the human cytochrome P450 system, particularly the isozymes CYP2C9 and CYP3A4. • In theory, therefore, fluconazole decreases the metabolism and increases the concentration of any drug metabolised by these enzymes. • Additionally, its potential effect on QT interval increases the risk of cardiac arrhythmia if used concurrently with other drugs that prolong the QT interval.

  11. Side of Effects

  12. Adverse Reactions/Toxic Effects

More Related