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Multistep Progression of Neoplasia

Multistep Progression of Neoplasia. Carcinoma-in-situ vs. Invasive carcinoma. Normal colorectal mucosa. Low-grade dysplasia. High-grade dysplasia. TNM SYSTEM. N1 = 1-3 nodes involved N2 = more than 3 nodes involved M. a = involvement of other organ b = peritoneal involvement.

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Multistep Progression of Neoplasia

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  1. Multistep Progression of Neoplasia Carcinoma-in-situ vs. Invasive carcinoma

  2. Normal colorectal mucosa Low-grade dysplasia High-grade dysplasia

  3. TNM SYSTEM N1 = 1-3 nodes involved N2 = more than 3 nodes involved M a = involvement of other organ b = peritoneal involvement

  4. DUKES STAGING OF COLORECTAL CANCER

  5. Haggitt Staging (peduculated polyp) Carcinoma Arising in Colorectal Polyp Kikuchi Staging (sessile polyp)

  6. MESORECTAL EXCISION

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