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Pyridinium Dichromate (PDC): The Corey-Schmidt Reagent

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Pyridinium Dichromate (PDC): The Corey-Schmidt Reagent

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  1. Formal total synthesis of (-)-balanol: a potent PKC inhibitor. Yaragorla, Srinivasarao; Muthyala, Ramaiah. Center for Orphan Drug Research, Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, USA. Tetrahedron Letters (2010), 51(3), 467-470.

  2. Pyridinium Dichromate (PDC): The Corey-Schmidt Reagent Pyridinium dichromate (PDC) is a commercially available (and also readily prepared) salt of chromic acid that is soluble in many common organic solvents and useful in the oxidation of alcohols to aldehydes and ketones. It is less acidic than pyridinium chlorochromate (PCC), and thus more suitable for the oxidation of acid-sensitive substrates.

  3. Pyridinium Chlorochromate (PCC) Corey-Suggs Reagent

  4. Elias J. Corey Professor Emeritus, Harvard University Nobel Prize Winner:

  5. Shi Epoxidation Oxone = Potassium Peroxymonosulfate =

  6. Mechanism of the Shi Epoxidation Chiral Dioxirane

  7. Yian Shi Colorado State University

  8. The chiral catalyst of the Shi Epoxidation is derived from the readily-available D-Fructose Chiral Ketone Catalyst

  9. Dimethyldioxirane (DMDO)

  10. Trost Asymmetric Allylic Alkylation Reaction Barry Trost Stanford University Palladium p-allyl complex

  11. Methods for Reduction of Azides to Amines

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