Anazole Tablets (Generic Anastrozole Tablets)

1. Anazole Tablets (Generic Anastrozole Tablets) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Anazole Tablets (Generic Anastrozole Tablets) Anazole Tablets (Generic Anastrozole Tablets) manufactured by Alpha Pharma Healthcare Private Limited, India are used for adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer. This medicine has also been used to prevent breast cancer in those at high risk. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Anazole Tablets (Generic Anastrozole Tablets) Active Ingredient The active ingredient present in Anazole tablets is Anastrozole. Each Anazole tablet contains 1 mg of Anastrozole. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Anazole Tablets (Generic Anastrozole Tablets) Chemical Structure The structure of Anastrozole is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Anazole Tablets (Generic Anastrozole Tablets) Anazole Tablets are manufactured by Alpha Pharma Healthcare Private Limited, India in the strength of 1 mg. ( Website: https://www.alpha-pharma.com/ https://www.alpha-pharma.com/ ) URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Anazole Tablets (Generic Anastrozole Tablets) Anastrozole Tablets – Brand Names Anastrozole tablets are available under various drug trade names that include Arimidex, Aremed, Anazole, Altraz, Armotraz, Anabrez, Anashil and Redest. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Anazole Tablets (Generic Anastrozole Tablets) Uses of Anazole Tablets Anazole Tablets (Generic Anastrozole Tablets) is used to treat early hormone receptor-positive breast cancer. It is also used for first-line treatment of hormone receptor-positive or hormone receptor-unknown advanced or metastatic (cancer that has spread) breast cancer. Anastrozole is also used to treat advanced breast cancer that has grown or spread after tamoxifen treatment. This medicine is used only in women who have already stopped menstruating (postmenopausal). Many breast cancer tumors grow in response to estrogen. This medicine interferes with the production of estrogen in the body. As a result, the amount of estrogen that the tumor is exposed to is reduced, limiting the growth of the tumor. Efficacy has not been demonstrated in oestrogen receptor negative patients unless they had a previous positive clinical response to Tamoxifen. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Anazole Tablets (Generic Anastrozole Tablets) Anazole Tablets Dosage The dosage of Anazole tablets Anazole tablets (Generic Anastrozole Tablets) is given below: The recommended dosage of Anazole tablets is orally once a day, with or without meals. The dosage is given below: The dose of Anazole (Generic Anastrozole Tablets) is one 1 mg tablet taken once a day. For patients with advanced breast cancer, Anazole should be continued until tumor progression. Anastrozole Tablets can be taken with or without food. For adjuvant treatment of early breast cancer in postmenopausal women, the optimal duration of therapy is unknown. No changes in dose are recommended for patients with mild-to- moderate hepatic impairment. This medicine has not been studied in patients with severe hepatic impairment. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Anazole Tablets (Generic Anastrozole Tablets) Anazole Tablets Contraindications Anazole tablets are contraindicated in patients with a hypersensitivity to Anastrozole or any other component of this medication. Anazole Tablets are also contraindicated in women of premenopausal endocrine status, including pregnant women. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Anazole Tablets (Generic Anastrozole Tablets) Storage Instructions Anazole tablets (Generic Anastrozole tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Anazole Tablets (Generic Anastrozole Tablets) Warnings Since Anastrozole lowers circulating oestrogen levels it may cause a reduction in bone mineral density with a possible consequent increased risk of fracture. Consider bone mineral density monitoring. In women with pre-existing ischemic heart disease, an increased incidence of ischemic cardiovascular events was observed with Anastrozole Tablets (Anazole). More patients being administered Anastrozole tablets were reported to have elevated serum cholesterol compared to patients receiving Tamoxifen. Consider cholesterol monitoring. Anastrozole has not been investigated in breast cancer patients with moderate or severe hepatic impairment. Exposure to Anastrozole can be increased in subjects with hepatic impairment. Administration of Anastrozole in patients with moderate and severe hepatic impairment must be performed with caution. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Anazole Tablets (Generic Anastrozole Tablets) Warnings Anastrozole has not been investigated in breast cancer patients with severe renal impairment. Exposure to Anastrozole is not increased in subjects with severe renal impairment (GRF less than 30 ml/min ). In patients with severe renal impairment, administration of Anastrozole must be performed with caution. Anastrozole is not recommended for use in children and adolescents as safety and efficacy have not been established in this group of patients. This medicine may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. Since this medicine can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Anazole Tablets (Generic Anastrozole Tablets) Anazole Tablets Side Effects In the early breast cancer (ATAC) study, the most common side effects with an incidence rate of more than 10% occurring in women taking Anastrozole (Anazole tablets) included: hot flashes, asthenia, arthritis, pain, arthralgia, pharyngitis, hypertension, depression, nausea and vomiting, rash, osteoporosis, fractures, back pain, insomnia, headache, peripheral edema and lymphedema, regardless of causality. In the advanced breast cancer studies, the most common side effects with an incidence rate of more than 10% occurring in women taking Anastrozole (Anazole tablets) included: hot flashes, nausea, asthenia, pain, headache, back pain, bone pain, increased cough, dyspnea, pharyngitis and peripheral edema. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Anazole Tablets (Generic Anastrozole Tablets) Anazole Tablets Overdose Clinical trials have been conducted with Anastrozole (Anazole tablets), up to 60 mg in a single dose given to healthy male volunteers and up to 10 mg daily given to postmenopausal women with advanced breast cancer; these dosages were tolerated. A single dose of Anastrozole that results in life-threatening symptoms has not been established. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Anazole Tablets (Generic Anastrozole Tablets) Treatment of Anazole Tablets Overdose There is no specific antidote to Anastrozole (Anazole tablets) overdosage and treatment must be symptomatic. In the management of an overdose, consider that multiple agents may have been taken. Vomiting may be induced if the patient is alert. Dialysis may be helpful because Anastrozole is not highly protein bound. General supportive care, including frequent monitoring of vital signs and close observation of the patient, is indicated. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Anazole Tablets (Generic Anastrozole Tablets) Anazole Tablets During Pregnancy Anastrozole (Anazole tablets) has been classified by the US FDA as Anastrozole (Anazole tablets) has been classified by the US FDA as Pregnancy Category X. Pregnancy Category X. Anastrozole (Anazole tablets) may cause fetal harm when administered to a pregnant woman and offers no clinical benefit to premenopausal women with breast cancer. Anastrozole tablets are contraindicated in women who are or may become pregnant. In animal studies, Anastrozole (Anazole tablets) caused pregnancy failure, increased pregnancy loss, and signs of delayed fetal development. There are no studies of Anastrozole tablets use in pregnant women. If Anastrozole is used during pregnancy, or if the patient becomes pregnant while receiving this medicine, the patient should be apprised of the potential hazard to the fetus and potential risk for pregnancy loss. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Anazole Tablets (Generic Anastrozole Tablets) For more details on Anazole Tablets click here Anazole Tablets click here Anazole Tablets (Generic Anastrozole Tablets) by Alpha Pharma Healthcare Private Limited, India. URL: URL: https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html https://www.clearskypharmacy.biz/generic-arimidex-anazole-by-alpha-pharma.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )