1 / 13

Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

Effect of a 6-day icv ghrelin infusion (2.5 nmol/d) on cumulative food intake (A), body weight gain (B), food efficiency (C), and fat mass gain (D). Values are mean ± SEM of 6–7 animals per group *P < 0.05 versus control; #P < 0.05 versus ghrelin-pf.

deion
Download Presentation

Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Effect of a 6-day icv ghrelin infusion (2.5 nmol/d) on cumulative food intake (A), body weight gain (B), food efficiency (C), and fat mass gain (D) Values are mean ± SEM of 6–7 animals per group*P < 0.05 versus control; #P < 0.05 versus ghrelin-pf Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  2. Effects of icv ghrelin infusion on total energy expenditure and RQ Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  3. Effects of icv ghrelin infusion on plasma bioactive ghrelin, glucose, insulin, corticosterone, leptin, FFA, and TG levels Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  4. Effect of a 6-day icv ghrelin infusion (2.5 nmol/day) on insulin-stimulated glucose utilization indices measured during euglycemic-hyperinsulinemic clamps in epididymal WAT (A), inguinal WAT (B), BAT (C), and soleus muscle (D) Values are mean ± SEM of 6–7 animals per group *P < 0.05 versus control; #P < 0.05 versus ghrelin-pf Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  5. Effect of a 6-day icv ghrelin infusion (2.5 nmol/d) on epididymal WAT mRNA expression of LPL (A), ACC (B), and CPT-1α (C) Values are mean ± SEM of 6–7 animals per group *P < 0.05 versus control; #P < 0.05 versus ghrelin-pf Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  6. Effect of a 6-day icv ghrelin infusion (2.5 nmol/d) on epididymal WAT mRNA expression of FAS (A) and SCD1 (B), and on epididymal protein expression of WAT FAS (C) and SCD1 (D), with one representative Western blot (of the 2 performed) Values are mean ± SEM of 6–7 animals per group *P < 0.05 versus control; #P < 0.05 versus ghrelin-pf Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  7. Effect of a 6-day icv ghrelin infusion (2.5 nmol/d) on BAT UCP1 (A) and UCP3 (B) Values are mean ± SEM of 6–7 animals per group. *P < 0.05 versus control Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  8. Effects of acute and chronic icv ghrelin infusion on mRNA expression of LPL, ACC, FAS, and SCD1 in epididymal WAT Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  9. Effects of peripheral ghrelin infusion on mRNA expression of ACC, FAS, SCD1, LPL, and CPT-1αin epididymal WAT and UCP1 and UCP3 in BAT Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  10. Effect of a 6-day icv ghrelin infusion (2.5 nmol/d) on hypothalamic NPY mRNA expression Values are mean ± SEM of 6–7 animals per group. *P < 0.05 versus control Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  11. Effect of a 6-day icv ghrelin infusion (2.5 nmol/day) on cumulative food intake (A and B) and body weight gain (C and D) in WT and TKO mice Values are mean ± SEM of 6–7 animals per group. *P < 0.05 versus control Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  12. Epididymal WAT mRNA expression of LPL (A) and SCD1 (B) in WT and ghrelin KO mice Values are mean ± SEM of 5 animals per group. *P < 0.05 versus WT Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

  13. Primer sequences used for real-time RT-PCR Claudia Theander-Carrillo, et al. J. Clin. Invest. 2006 116:1983-93

More Related