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Occupational Exposure to Tuberculosis

Occupational Exposure to Tuberculosis. Objectives. Provide a basic understanding regarding the transmission and pathogenesis of M. tuberculosisDiscuss the epidemiology of tuberculosis (TB) in the U.S. and N.C.Provide an overview regarding the enforcement procedures for occupational exposure to T

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Occupational Exposure to Tuberculosis

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    1. Occupational Exposure to Tuberculosis The information in this presentation is provided voluntarily by the N.C. Department of Labor, Education Training and Technical Assistance Bureau as a public service and is made available in good faith. This presentation is designed to assist trainers conducting OSHA outreach training for workers. Since workers are the target audience, this presentation emphasizes hazard identification, avoidance, and control – not standards. No attempt has been made to treat the topic exhaustively. It is essential that trainers tailor their presentations to the needs and understanding of their audience. The information and advice provided on this Site and on Linked Sites is provided solely on the basis that users will be responsible for making their own assessment of the matters discussed herein and are advised to verify all relevant representations, statements, and information. This presentation is not a substitute for any of the provisions of the Occupational Safety and Health Act of North Carolina or for any standards issued by the N.C. Department of Labor. Mention of trade names, commercial products, or organizations does not imply endorsement by the N.C. Department of Labor. Revised and Updated by E Geddie/W Lagoe 06 2011 The information in this presentation is provided voluntarily by the N.C. Department of Labor, Education Training and Technical Assistance Bureau as a public service and is made available in good faith. This presentation is designed to assist trainers conducting OSHA outreach training for workers. Since workers are the target audience, this presentation emphasizes hazard identification, avoidance, and control – not standards. No attempt has been made to treat the topic exhaustively. It is essential that trainers tailor their presentations to the needs and understanding of their audience. The information and advice provided on this Site and on Linked Sites is provided solely on the basis that users will be responsible for making their own assessment of the matters discussed herein and are advised to verify all relevant representations, statements, and information. This presentation is not a substitute for any of the provisions of the Occupational Safety and Health Act of North Carolina or for any standards issued by the N.C. Department of Labor. Mention of trade names, commercial products, or organizations does not imply endorsement by the N.C. Department of Labor. Revised and Updated by E Geddie/W Lagoe 06 2011

    2. Occupational Exposure to Tuberculosis The information in this presentation is provided voluntarily by the N.C. Department of Labor, Education Training and Technical Assistance Bureau as a public service and is made available in good faith. This presentation is designed to assist trainers conducting OSHA outreach training for workers. Since workers are the target audience, this presentation emphasizes hazard identification, avoidance, and control – not standards. No attempt has been made to treat the topic exhaustively. It is essential that trainers tailor their presentations to the needs and understanding of their audience. The information and advice provided on this Site and on Linked Sites is provided solely on the basis that users will be responsible for making their own assessment of the matters discussed herein and are advised to verify all relevant representations, statements, and information. This presentation is not a substitute for any of the provisions of the Occupational Safety and Health Act of North Carolina or for any standards issued by the N.C. Department of Labor. Mention of trade names, commercial products, or organizations does not imply endorsement by the N.C. Department of Labor. Revised and Updated by E Geddie/W Lagoe 06 2011 The information in this presentation is provided voluntarily by the N.C. Department of Labor, Education Training and Technical Assistance Bureau as a public service and is made available in good faith. This presentation is designed to assist trainers conducting OSHA outreach training for workers. Since workers are the target audience, this presentation emphasizes hazard identification, avoidance, and control – not standards. No attempt has been made to treat the topic exhaustively. It is essential that trainers tailor their presentations to the needs and understanding of their audience. The information and advice provided on this Site and on Linked Sites is provided solely on the basis that users will be responsible for making their own assessment of the matters discussed herein and are advised to verify all relevant representations, statements, and information. This presentation is not a substitute for any of the provisions of the Occupational Safety and Health Act of North Carolina or for any standards issued by the N.C. Department of Labor. Mention of trade names, commercial products, or organizations does not imply endorsement by the N.C. Department of Labor. Revised and Updated by E Geddie/W Lagoe 06 2011

    3. Objectives Provide a basic understanding regarding the transmission and pathogenesis of M. tuberculosis Discuss the epidemiology of tuberculosis (TB) in the U.S. and N.C. Provide an overview regarding the enforcement procedures for occupational exposure to TB

    4. Reported TB Cases*, United States

    5. TB Morbidity, United States

    6. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5910a2.htm#fig1http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5910a2.htm#fig1

    7. TB Case Rates for N.C. and U.S.

    8. North Carolina 2009 TB Cases Graphic from http://www.epi.state.nc.us/epi/tb/ Graphic from http://www.epi.state.nc.us/epi/tb/

    9. Graphic from CDCGraphic from CDC

    10. Transmission of M. Tuberculosis Spread by droplet nuclei (1-5 µm) Expelled when person with infectious TB coughs, sneezes, speaks, or sings Close contacts at highest risk of becoming infected Transmission occurs from person with infectious TB disease (not latent TB infection)

    11. Probability of TB Transmission Infectiousness of person with TB Environment in which exposure occurred Duration of exposure Virulence of the organism Photo from MS ClipartPhoto from MS Clipart

    12. TB Pathogenesis - Latent TB Infection Once inhaled, bacteria travel to lung alveoli and establish infection 2–12 wks after infection, immune response limits activity; infection is detectable Some bacteria survive and remain dormant but viable for years (latent TB infection, or LTBI)

    13. Persons with LTBI are: Asymptomatic Not infectious LTBI formerly diagnosed only with tuberculin skin testing (TST) Now QuantiFeron – TB Gold Test (QFT-G) can be used MS Clip Art MS Clip Art

    14. TB Pathogenesis - Active TB Disease LTBI progresses to TB disease in: Small number of persons soon after infection 5%–10% of persons with untreated LTBI sometime during lifetime About 10% of persons with HIV and untreated LTBI per year MS Clip Art MS Clip Art

    15. Pathogenesis 10% of infected persons with normal immune systems develop TB at some point in life HIV strongest risk factor for development of TB if infected Risk of developing TB disease 7% to 10% each year Certain medical conditions increase risk that TB infection will progress to TB disease

    16. Conditions That Increase Risk… ….of progression to TB disease HIV infection Substance abuse Recent infection Chest radiograph findings suggestive of previous TB Diabetes mellitus Silicosis Cancer of the head and neck MS Clip Art MS Clip Art

    17. ….of progression to TB disease Hematologic and reticuloendothelial diseases End-stage renal disease Intestinal bypass or gastrectomy Chronic malabsorption syndromes Low body weight (10% or more below the ideal) Prolonged corticosteroid therapy Other immunosuppressive therapy MS Clip Art MS Clip Art

    18. Common Sites of TB Disease Lungs Pleura Central nervous system Lymphatic system Genitourinary systems Bones and joints Disseminated (miliary TB) Clipart courtesy of CDCClipart courtesy of CDC

    19. Drug-Resistant TB Drug-resistant TB transmitted same way as drug-susceptible TB Drug resistance is divided into two types: Primary resistance develops in persons initially infected with resistant organisms Secondary resistance (acquired resistance) develops during TB therapy MS Clip Art MS Clip Art

    20. First-Line Anti-TB Drugs Isoniazid (INH) Rifampin (RIF) Pyrazinamide (PZA) Ethambutol (EMB) or Streptomycin (SM)* MS Clip ArtMS Clip Art

    21. Second-Line Anti-TB Drugs Capreomycin Kanamycin Amikacin Ethionamide Para-aminosalicylic acid Cycloserine Ciprofloxacin* Ofloxacin* Levofloxacin* Clofazamine

    22. OSHA Instruction CPL 2.106 Enforcement Procedures and Scheduling for Occupational Exposure to Tuberculosis MS Clip Art MS Clip Art

    23. Inspection Scheduling and Scope Inspections conducted in response to: Employee complaints Related fatality/catastrophes Part of all industrial hygiene inspections in covered facilities MS Clip ArtMS Clip Art

    24. Covered Facilities Health care facilities Include hospitals where patients w/ confirmed or suspect TB are treated or transported Non-hospital health care settings Applies only to personnel present during performance of high-hazard procedures Dental personnel covered only if treat suspect or confirmed active TB patients in hospital or correctional facility MS Clip ArtMS Clip Art

    25. Correctional institutions Long-term care facilities for the elderly Homeless shelters Present unique problems for protection of workers Must establish protocols for rapid early identification followed by immediate transfer if shelter not treating patients Drug treatment centers Covered Facilities MS Clip ArtMS Clip Art

    26. Inspection Procedures Has the facility had a suspect or confirmed active case within previous 6 months? No, TB enforcement procedures do not apply Yes, CSHO to proceed with TB portion of inspection MS Clip ArtMS Clip Art

    27. Inspection Procedures Employer’s TB plan will be verified through employee interviews and direct observation where feasible When smoke-trail visualization tests are used Be prepared to present MSDS for smoke MS Clip ArtMS Clip Art

    28. Citation Policy Employers who have employees occupationally exposed to TB must comply with the following provisions: NCGS 95-129(1) -- General Duty Clause 29 CFR 1910.134 -- Respiratory Protection 29 CFR 1910.145 -- Accident Prevention Signs and Tags 29 CFR 1910.1020 -- Access to Employee Exposure and Medical Records 29 CFR 1904 -- Recording & Reporting Occupational Injuries & Illnesses MS Clip ArtMS Clip Art

    29. NCGS: 95-129(1) Each employer shall furnish to each of his employees conditions of employment and a place of employment which are free from recognized hazards that are causing or are likely to cause death or serious physical harm to his employees. General Duty Clause (Photo courtesy of osha.gov) (Photo courtesy of osha.gov)

    30. General Duty Clause Violation Four Required Elements The employer failed to keep the workplace free of a hazard to which employees of that employer were exposed; The hazard was recognized in the industry; The hazard was causing or likely to cause death or serious physical harm; and There was a feasible and useful abatement method to correct (abate) the hazard.

    31. Invoking the General Duty Clause The basis of a General Duty Clause violation is exposure to the hazard, not the absence of a particular abatement method. (Picture courtesy of NCDOL website) (Picture courtesy of NCDOL website)

    32. Recognizing Exposure to a Serious Hazard Employers with employees working in one of the high risk occupational settings, When employees not provided with appropriate protection, and They have occupational exposure to TB. MS Clip ArtMS Clip Art

    33. Occupational Exposure to Tuberculosis Exposure to exhaled air of an individual with suspected or confirmed pulmonary TB disease, or Employee exposure without appropriate protection to a high hazard procedure performed on individual with suspected or confirmed infectious TB disease and which has potential to generate infectious airborne droplet nuclei.

    34. High Hazard Procedures Aerosolized medication treatment Bronchoscopy Sputum induction Endotracheal intubation and suctioning procedures Emergency dental procedures Endoscopic procedures Autopsies conducted in hospitals (Photo courtesy of MS Clip Art) (Photo courtesy of MS Clip Art)

    35. Feasible and Useful Abatement Methods Early identification of patient/client Employer must implement a protocol for early identification of individuals with active TB Program must identify and characterize each area within the facility Characteristics of effective TB IC program (see Table 3, CDC Guidelines) Clip Art Source: CDC.GovClip Art Source: CDC.Gov

    36. Medical Surveillance Initial exams TB skin tests (at no cost to employees) to: Current potentially exposed employees All new employees prior to exposure Graphic from National Institute of Health website.Graphic from National Institute of Health website.

    37. Two-Step TB Skin Test Two-step baseline required for new employee Who have initially a negative PPD test, and Who have not had a documented negative TB skin test in previous 12 months. TB skin tests to be offered at time and location convenient to workers.

    38. Medical Surveillance Periodic evaluations TB skin testing to be conducted for workers in following categories: High risk -- every 3 months Intermediate risk -- every 6 months Low risk -- annually Exemption for workers with positive skin test who received treatment for disease or preventive therapy for infection Reassessment is required following exposure or change in health

    39. Case management of infected employees must include: Protocol for new converters Conversion to positive TB skin test to be followed ASAP by appropriate evaluations Physical Laboratory Radiographic Work restrictions for infectious employees Medical Surveillance MS Clip ArtMS Clip Art

    40. Worker Education and Training Training to be repeated as needed Elements: Mode of TB transmission Signs and symptoms of TB Medical surveillance and therapy Site specific protocols (including purpose and use of controls ) Recognition of suspected TB disease MS Clip ArtMS Clip Art

    41. Engineering Controls Individuals with suspected or confirmed infectious TB disease must be placed in an AFB isolation room. High hazard procedures must be performed in: AFB isolation treatment rooms AFB isolation rooms, booths, and/or hoods. Photo courtesy of University of Auckland Photo courtesy of University of Auckland

    42. Isolation and treatment rooms in use by individuals with suspected or confirmed infectious TB disease shall be kept under negative pressure (smoke test, etc.). Engineering Controls Clip Art: OSHA.govClip Art: OSHA.gov

    43. Air exhausted from AFB isolation or treatment rooms must be exhausted directly outside and not recirculated into general ventilation system. Where recirculation unavoidable, HEPA filters to be installed in duct system from room to general ventilation. HEPA filters to be monitored on regular schedule Engineering Controls

    44. All potentially contaminated air which is ducted through facility must be kept under negative pressure until safely discharged outside (i.e., away from occupied areas and air intakes), or Air from isolation and treatment rooms must be decontaminated by a recognized process (e.g., HEPA filter) before recirculated back to isolation/treatment room. Use of UV radiation as the sole means of decontamination shall not be used. Engineering Controls Photo: NCDOL-OSH Division Photo: NCDOL-OSH Division

    45. If high hazard procedures performed within AFB isolation or treatment rooms Without source control or local exhaust ventilation and droplets released into environment Purge time interval must be imposed during which respirators required when entering room Interim or supplemental ventilation units equipped with HEPA filters are acceptable Engineering Controls OSHA.govOSHA.gov

    46. Respiratory Protection Respirators shall be provided by the employer when such equipment is necessary to protect the health of the employee. The employer shall provide the respirators which are applicable and suitable for the purpose intended. The employer shall be responsible for the establishment and maintenance of a respiratory protection program. MS Clip ArtMS Clip Art

    47. NIOSH respirator certification criteria (42 CFR Part 84 Subpart K) Flow rate of 85 L/min Tested for penetration by particles with median Aerodynamic diameter of 0.3 ?m Three categories of certified respirators Type 100 (99.97% efficient) Type 99 (99% efficient) Type 95 (95% efficient) -- minimum for TB Respiratory Protection OSHA.govOSHA.gov

    48. HEPA respirators or respirators certified under 42 CFR Part 84 Subpart K are required: When workers enter rooms housing individuals with suspected or confirmed infectious TB When workers present during performance of high hazard procedures on individuals with suspected or confirmed infectious TB When emergency-medical-response personnel or others transport, in a closed a vehicle, an individual with suspected or confirmed infectious TB

    49. Respirator Program Requirements Written operating procedures Proper selection Training and fitting Cleaning and disinfecting Storage Inspection and maintenance Work area surveillance Inspection/evaluation of program Approved respirators Graphic from MS ClipartGraphic from MS Clipart

    50. Employee Medical/Exposure Records Employee access to records A record concerning employee exposure to TB is an employee exposure record. A record of TB skin test results and medical evaluations and treatment are employee medical records. MS Clip ArtMS Clip Art

    51. Accident Prevention Signs and Tags A warning shall be posted outside the respiratory isolation or treatment room or a message referring one to the nursing station for instruction may be posted. Clip Art: CDC.govClip Art: CDC.gov

    52. A signal word/phrase (“STOP”, “HALT”, “NO ADMITTANCE”), or Biohazard symbol and major message (“RESPIRATORY ISOLATION” or “AFB ISOLATION”) along with necessary precautions. Biological hazard tags are also required on air transport components (e.g., fans, ducts, filters) that transport contaminated air.

    53. OSHA 300 Log Both TB infections (positive skin test) and TB disease are recordable Original entry must be updated if TB infection progresses to TB disease during 5 year maintenance period Positive skin test within first 2 weeks of employment does not have to be recorded on the OSHA 300 form

    54. Outreach and Assistance NC Department of Labor 1-800-NCLABOR http://www.ncdol.com Consultative Services 1-800-NCLABOR or (919) 807-2899 Education, Training and Technical Assistance 1-800-NCLABOR or (919) 807-2875 NIOSH 1-800-35-NIOSH http://www.cdc.gov/niosh/homepage.html Graphic from MS Clipart Graphic from MS Clipart

    55. Thank You For Attending! Final Questions?

    56. Handouts Place all handouts at the end of this presentation.

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