1 / 13

Speciation and Melanin Production

Speciation and Melanin Production. Evolution of the MC1R gene. MC1R gene. MC1R = cell membrane receptor, 317 aa long Binds to melanin stimulating hormone. This binding causes change in MC1R protein that makes tyrosinase that then makes black melanin ( eumelanin ).

dougal
Download Presentation

Speciation and Melanin Production

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Speciation and Melanin Production Evolution of the MC1R gene

  2. MC1R gene • MC1R = cell membrane receptor, 317 aa long • Binds to melanin stimulating hormone. This binding causes change in MC1R protein that makes tyrosinasethat then makes black melanin (eumelanin). • Lack of MSH does not produce tyrosinase and then only pheomelanin(yellow/red) is produced.

  3. Albinism mutation: • Mutation in gene coding for tyrosinase. Chromosome 11. • No melanin (red or black) can be produced.

  4. Soloman Flycatchers Chestnut-bellied flycatcher (Makira Island) Black-bellied flycatcher (Santa Ana Island)

  5. Sexual Selection

  6. In humans:

  7. Redhead gene a mutation: • Chromosome 16, amino acid #151 changed from argenine to cysteine • Redheads only produce the red/brown type of melanin (pheomelanin)

  8. G-Protein coupled Receptors (GPCR) – inherited proteins

  9. G- Protein Coupled Receptors

  10. GPCR = largest family of proteinsFound in all 3 domainsOf 30,000 human genes, 1000 are GCPR

  11. 5% of mammal DNA are GCPR for odorPrimates have only 300 odor receptors-(others have mutation with stop codon within them)

  12. Vision receptors are CGPR

  13. Taste is a GPCR too!

More Related