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Survival (days)

a. b. 1.0 0.8 0.6 0.4 0.2 0.0. 1.0 0.8 0.6 0.4 0.2 0.0. OV-90 OV-90: CCL2 49. OV-90 OV-90: CCL2 23. Cumulative survival. Cumulative survival. p=0.001. p=0.001. 40 60 80 100. 20 40 60 80 100 120.

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Survival (days)

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  1. a b 1.0 0.8 0.6 0.4 0.2 0.0 1.0 0.8 0.6 0.4 0.2 0.0 OV-90 OV-90:CCL249 OV-90 OV-90:CCL223 Cumulative survival Cumulative survival p=0.001 p=0.001 40 60 80 100 20 40 60 80 100 120 Survival (days) Survival (days) c d 1.0 0.8 0.6 0.4 0.2 0.0 1.0 0.8 0.6 0.4 0.2 0.0 OV-90:EV2 OV-90:CCL249 OV-90:EV2 OV-90:CCL223 Cumulative survival Cumulative survival p=0.001 P<0.001 60 80 100 120 50 60 70 80 90 100 110 Survival (days) Survival (days) e f 1.0 0.8 0.6 0.4 0.2 0.0 1.0 0.8 0.6 0.4 0.2 0.0 OV-90:EV9 OV-90:CCL249 OV-90:EV9 OV-90:CCL223 Cumulative survival Cumulative survival p=0.001 p=0.001 60 80 100 120 50 60 70 80 90 100 110 Survival (days) Survival (days)

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