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Jacques Normand, Ph.D. Director, AIDS Research Program National Institute on Drug Abuse

NIDA’s New HIV/AIDS Research Program. Jacques Normand, Ph.D. Director, AIDS Research Program National Institute on Drug Abuse. Objectives. Update on NIDA’s New AIDS Research Program CAMCODA NIDA Council Recommendations New AIDS Research Program Structure Research Priorities

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Jacques Normand, Ph.D. Director, AIDS Research Program National Institute on Drug Abuse

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  1. NIDA’s New HIV/AIDS Research Program Jacques Normand, Ph.D. Director, AIDS Research Program National Institute on Drug Abuse

  2. Objectives • Update on NIDA’s New AIDS Research Program • CAMCODA • NIDA Council Recommendations • New AIDS Research Program • Structure • Research Priorities • Brief Update on NIDA/NIH Collaborative Projects • Projects and Partners • New HPTN Network Drug Abuse Projects

  3. CAMCODA Structure Director Deputy Director Population-Based Intervention Unit Human Development Unit Medical Consequence Unit Staff: 20 Professionals

  4. NIDA AIDS FY03 AIDS Funding by Divisions

  5. NIDA Advisory Council Workgroup on HIV/AIDS Report on Findings and Recommendations February, 2004

  6. Structural & Procedural Recommendations • Create new position of “Director, AIDS Research Program” reporting to NIDA’s Director • Update policy/procedures to determine which projects qualify for AIDS funding • Improve articulation of HIV/AIDS mission and planning processwithin & acrossDivisions/Centers • Increase interaction across NIH, and with extramural community

  7. NIDA’s AIDS Research Program Structure AIDS Research Program Mission: Plan, develop, coordinate and integrate research priorities within NIDA and externally. Staff: Jacques Normand Lynda Erinoff Helen Cesari AIDS Workgroup AIDS Coding Subgroup External Scientific AIDS Workgroup TBA

  8. NIDA’s AIDS Workgroup Membership • Division of Pharmacotherapies and Medical Consequences of Drug Abuse • Jag Khalsa • Ahmed Elkashef • Jamie Biswas • Division of Basic Neurosciences and Behavioral Research • Diane Lawrence • Cora Lee Wetherington • Charles Sharp • Yu Lin • Minda Lynch

  9. NIDA’s AIDS Workgroup Membership (Cont.) Division of Epidemiology, Services, and Prevention Research Elizabeth Lambert Division of Clinical Neurosciences, Development and Behavioral Treatment Lisa Onken Melissa Racioppo Nicolette Borek Ro Nemeth Center for Clinical Trials Network Mary Ellen Michel

  10. NIDA’s AIDS Workgroup Membership (Cont.) • Office of Science Policy & Communication • Anna Staton • International Program • Steve Gust • Intramural Research Program • John Schmittner • Office of Extramural Affairs • Mark Green • Office of Planning & Research Management • Stacy Gardner

  11. External Scientific AIDS Workgroup Proposed Membership (~ 8): Council Members Nominee per Division/Center Nominee from AIDS Program Proposed Task: Review NIDA’s AIDS Strategic Plan Review & make recommendations on new AIDS related procedural change (e.g., definition of AIDS and coding guidelines) Review NIDA’s priorities/initiatives

  12. FY04 AIDS Funding by NIDA Divisions

  13. NIDA’s FY04 Funding By OAR Research Areas of Emphasis • Natural History and Epidemiology $54,246,859 • Etiology and Pathogenesis$29,028,598 • Therapeutics $12,084,141 • Vaccines$1,983,201 • Behavioral and Social Science$186,583,465 • Training, Infrastructure, and Capacity Building $6,860,742 7. Information Dissemination $1,594,994

  14. Research Priority Recommendations Update programs with continuous review of epidemiologic and other findings • Racial/ethnic disparities • Emphasize case finding/treatment • HAART interactions/adherence/resistance Newer HIV/IDU epidemics (Russia, China, India, Eastern Europe) Test drug Tx for HIV prevention Emerging drugs (e.g., Meth/Viagra, NYC case/immunological & CNS impact ) Sexual risk behaviors (main exposure category) Adolescents (developmental/decision making, impulsivity) Role of drug abuse on transmission (drug type, partnership, context)

  15. Current NIDA’s AIDS Program Tasks • Explore new ways to attract new AIDS PIs • Better integrate HIV/AIDS within and across • NIDA Divisions/Centers and other NIH Institutes • Working on Generating FY07 OAR Priorities • (retooling priorities to establish strong presence in all Div/Ctr) • Will be Generating NIDA FY06 AIDS Initiatives • Developing Criteria for AIDS Grants • Will be Appointing Members to Extramural • Scientific AIDS Workgroup • Will be Developing NIDA’s HIV/AIDS Strategic Plan

  16. NIDA’s CollaborativeProjects

  17. HPTN & New NIAID Network • Current Projects • Epidemiology • HIV Prevention • Drug Tx as HIV Prevention • New Network • Proposed protocols • Community Scale-up; • Stimulant pharmacotherapy as HIV prevention

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