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Sun Protection & Vitamin D Controversy. Dr Jackie Dyche. Photoprotection. Sunlight main factor for BCC & SCC Association of MM & burning in childhood Strict protection from UVR recommended BUT 90% of Vit D has to be formed in the skin through the action of the sun. UV Light & Melanoma.
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Sun Protection & Vitamin D Controversy Dr Jackie Dyche
Photoprotection • Sunlight main factor for BCC & SCC • Association of MM & burning in childhood • Strict protection from UVR recommended • BUT 90% of Vit D has to be formed in the skin through the action of the sun
UV Light & Melanoma • Body site distribution • Sunnier European countries have lower mortality • Diagnostic drift responsible for reported increase in cases
Vitamin D deficiency • Cancer: breast, colon, prostate, ovary, lymphoma • Cardiovascular: MI, High BP • Autoimmune: MS, Type 1 DM • Infection: TB • Allergy: Asthma • Rheumatic disease: Rh A • Bone Health • All cause mortality
Vitamin D deficiency • Definition 20-30ng/ml • Widespread • At risk groups: elderly, obese, photosensitive, dark skin,
Vitamin D & the Skin • Maximal production with UVB • Active metabolite Calcitriol - role in cell growth & cancer prevention • Protective effect of less intense solar radiation can outweigh its mutagenic effect
Conclusions • Moderation of photoprotective advice? • Vitamin D supplementation in at-risk groups