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Cell Communication (Chpt. 11)

Cell Communication (Chpt. 11). Chapter 11. Overview of Cell Signaling. Signaling evolved early in history of life Communicating cells may be close together or far apart 3 stages of signaling are: reception, transduction, and response. Communicating cells .

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Cell Communication (Chpt. 11)

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  1. Cell Communication (Chpt. 11) Chapter 11

  2. Overview of Cell Signaling • Signaling evolved early in history of life • Communicating cells may be close together or far apart • 3 stages of signaling are: reception, transduction, and response

  3. Communicating cells

  4. Signal Reception and the Initiation of Transduction • A signal molecule binds to a receptor protein, causing the protein to change shape • Most signal receptors are plasma membrane proteins

  5. http://www.blackwellpublishing.com/matthews/rhodopsin.html

  6. Signal Transduction Pathways • Pathways relay signals from receptors to cellular responses • Protein phosphorylation, is a major mechanism of signal transduction • Certain small molecules and ions are key components of signaling pathways (second messengers)

  7. Cellular Responses to Signals • In response to a signal, a cell may regulate activities in the cytoplasm or transcription in the nucleus • Elaborate pathways amplify and specify the cell’s response to signals

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