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Research Retreat Current Overview

Research Retreat Current Overview. Tom Hostetter Vice Chairman for Research. Some Outcomes of Last Retreat 2009. Agre Society solidified Annual Research Day Distribution of CTSC resources Meeting with SOM and UH leaders regarding research issues. Research Award Costs ( $ millions).

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Research Retreat Current Overview

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  1. Research RetreatCurrent Overview Tom Hostetter Vice Chairman for Research

  2. Some Outcomes of Last Retreat 2009 • Agre Society solidified • Annual Research Day • Distribution of CTSC resources • Meeting with SOM and UH leaders regarding research issues

  3. Research Award Costs ( $ millions)

  4. Research Cost 2011- 2012

  5. Sources of Awards 2011- 2012($ millions)

  6. Selected Highlights 2012 Over 40 new or competing renewal grants, one half from NIH • VAMC- Highly Funded Programs in Implementation, Quality and Education Research Basic and applied studies of antibiotic resistance GREC revitalized • CV- High impact papers in Science and Nature 6 new RO1s and a DARPA grant Mukesh Jain elected VP of ASCI • Endo- NIH trials ACCORDION,EDIC Studies in diabetic retinopathy • GI- NIH funded Network for study of Barrett’s PPG for IBD

  7. Selected Highlights 2012 • Heme/Onc- Cancer Center renewed High impact papers in NEJM, PLOS Genetics, JBC, PNAS • ID- Progress in HIV and TB research Creation of ID and Immunology Institute Expansion of work in Uganda including CV Neuro, & Genetics • Renal/Htn- Leadership in NIH SPRINT and CRIC trials Ongoing participation in NIH Clinical Trials in Organ Transplantation 2 endowed faculty positions from Centers for Dialysis Care

  8. Underrepresented Areas • Topics - Human/Population Genetics - Outcome/Health Care Delivery - Comparative Effectiveness Research - Geriatrics • Grant Types - K grants - for early career - P and U grants – for multiple investigators - Industry

  9. Threats to Funding NIH budget has been declining in constant dollars about 10 years ( ARRA funds in 2009 and 2010 excepted) Sequestration of 5- 10% of NIH budget will lead to about 2500 fewer new grants funded

  10. FASEB

  11. Responses To Funding Threats • Industry support- now about 6 % of total

  12. Responses To Funding Threats • Industry support • Philanthropy Examples: Harrington Discovery Institute Centers for Dialysis Care

  13. Responses To Funding Threats • Industry support • Philanthropy • Widen range of Federal Sources CTSC cores and pilot grants AHRQ DOD PCORI

  14. Patient Centered Outcomes Institute (PCORI) • Part of the Affordable Care Act • 2013 Budget $390 million • PCORI approved 25 awards, totaling $40.7 million over three years, to fund patient-centered comparative clinical effectiveness research projects

  15. PCORI’sResearch Budget Distribution

  16. Responses To Funding Threats • Industry support • Philanthropy • Widen range of Federal Sources CTSC cores and pilot grants AHRQ DOD PCORI • Better grants to Traditional Federal Sources Multi PI / Team Collaboration with other departments / institutions

  17. Training • Med Students Theses • Residency short track • Grad Students Tuitions • F, T and K NIH Grants

  18. Medical Student Theses • Students are required to write a thesis. • They have 4 months of committed time and an optional summer block after 1st year. • About 8% work in the DOM for their theses • To let students know of your research, update your info on the ePortfolio site. https://casemed.case.edu/ePortfolioFaculty08/ • Also send email to Todd Fennimore, Director of the Office of   Medical Student Research, txf80@case.edu.

  19. RESEARCH BLOCK Medical Student Research Timeline Decide on a mentor for the summer and submit IRB applications & funding applications. Submit the research proposal and submit IRB application M.D. thesis due by January 15th of the 4th year Lepow Medical Student Research Day SUMMER RESEARCH Arrive at CWRU School of Medicine Year 3 Year 4 Year 1 Year 2 4 mo. Schedule Yr 3 including the research block Contact potential mentors for the summer with the idea of a project that leads into the research block in year 3. Begin investigating areas of research interest Lepow Medical Student Research Day Lepow Medical Student Research Day Research summary due the Friday after the end of the research block Research progress reports due at 1 and 2 month points Work on M.D. thesis

  20. Percent of Published Student Research 48% 29% The value of a research continuum including the summer between years 1 & 2 as well as the research block in year 3. Courtesy of Jim Bruzik

  21. Training • Med Students Theses • Residency Short Track • Grad Students Tuitions • F, T and K NIH Grants

  22. Graduate Student Support by DOM Selected PhD students enrolled in SOM with a DOM PI DOM will pay their tuition PI must pay their stipend from grant, etc and division guarantee support for the term of the student’s course. About 20 students are being supported

  23. Break Outs • Breakout #1: Evolving NIH/Federal Funding Landscape      Leaders: Richard Walsh, MD & Fabio Cominelli, MD • Breakout #2:Mentoring and Career Development Leaders: Mukesh Jain, MD  & Aaron Proweller, MD • Breakout #3: Team Science and Multidisciplinary Research       Leaders: Amitabh Chak, MD, Stanton Gerson, MD& Robert Salata, MD • Breakout #4: Enhancing Industry-sponsored Research Opportunities       Leaders: Neal Meropol, MD,  & Marco Costa, MD, PhD

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