1 / 27

Cancer

Cancer. Transformation of normal cells to a nonnormal (cancer) cell Cancer cells may evade the immune system and proliferate to tumors Benign tumors do not spread – primary site of cancer Malignant tumors spread – secondary cancer sites Malignant tumors are said to be metastatic.

ina
Download Presentation

Cancer

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Cancer • Transformation of normal cells to a nonnormal (cancer) cell • Cancer cells may evade the immune system and proliferate to tumors • Benign tumors do not spread – primary site of cancer • Malignant tumors spread – secondary cancer sites • Malignant tumors are said to be metastatic

  2. Basic characteristics of cancer • Divide fast • Skip checkpoints of the cell cycle • Cells do not function normally • Cells do not exhibit density dependent inhibition • Cells do not exhibit anchorage dependency • Cells promote the growth of blood vessels • May synthesize growth factors to bypass cell cycle checkpoints • Cancer cells exhibit immortality (normal cells divide about 20-50 times)

  3. Types of cancer • Carcinoma – originate in external or internal coverings (epithelial tissue) • Skin, intestinal lining • Sarcomas – originate in support tissues of the body (connective tissue) • Bone, skeletal muscle • Leukemia/lymphoma – originate in the blood forming tissues of the body • Bone marrow, spleen, lymph nodes

  4. Melanoma (carcinoma) • Specifically affects the melanocytes of the skin’s epidermis • High probability of metastasis

  5. Intermittent sun exposure and severe sunburns Exposure to ultraviolet radiation due to atmospheric ozone depletion Excessive use of UV tanning beds Suppression of the immune system Carcinogenic risk factors coal, tar, and pitch (which are used in road paving and in some dyes); creosote (which is a wood preservative derived from tar); arsenic compounds (which are used in pesticides); and radium.

  6. Basal cell carcinoma Basal cell carcinoma can also be caused by overexposure to UV radiation. It typically affects only those areas of the body where this overexposure occurs.

  7. Squamous cell carcinoma Squamous cell carcinoma may also be caused by overexposure to UV radiation. It typically can be found anywhere on the body.

  8. A comparison of the 3 skin carcinomas

More Related