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Lorhandicap group: N Chau, JF Ravaud, E Bourgkard, J Sanchez, M Choquet,JP Meyer, C Otero Sierra,

Relationships of demanding work conditions with fatigue and psychotropic drug use: A community-based study. Lorhandicap group: N Chau, JF Ravaud, E Bourgkard, J Sanchez, M Choquet,JP Meyer, C Otero Sierra, JP Michaely, B Legras, F Guillemin, A Bhattacherjee, S Guillaume, A Dazord,

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Lorhandicap group: N Chau, JF Ravaud, E Bourgkard, J Sanchez, M Choquet,JP Meyer, C Otero Sierra,

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  1. Relationships of demandingwork conditions with fatigueand psychotropic drug use:A community-based study Lorhandicap group: N Chau, JF Ravaud, E Bourgkard, J Sanchez, M Choquet,JP Meyer, C Otero Sierra, JP Michaely, B Legras, F Guillemin, A Bhattacherjee, S Guillaume, A Dazord, L Méjean, N Tubiana-Rufi, Y Schléret, JM Mur INRS, Département Epidémiologie en Entreprises, Vandoeuvre-lès-Nancy, Inserm U420, INRS, Inserm U472, Inserm U502-CERMES, IFR25-RFRH, Script-Inserm, EA 3444, LIM, Hôpital Robert Debré APHP, CTNERHI, ORSAS (France), and Indian Institute of Technology (India) Investigation supported by the European Pole for Health

  2. Objective Demanding work conditions with multiple hazards can increase psychotropic drug use Assessment of the relationships of demanding work conditions with regular psychotropic drug use among employed people

  3. Materials and methods The sample: All subjects aged 15 or more from 8,000 households randomly selected from the Lorraine (north-eastern France) Mailed self-administrated questionnaire: • socio-demographical characteristics, smoking habit, alcohol use • highly demanding occupational hazards • regular psychotropic drug use (fatigue, headache, sleeplessness, nervousness or anguish)

  4. Study protocol (a) A request of participation by means of a questionnaire to ascertain the number of people in the household (b) Sending out standardized auto-questionnaires with a covering letter and a pre-paid envelope for reply (c) Sending a reminding letter without questionnaire (d) Sending questionnaires with a covering letter and a pre-paid envelope Communications addressed to the households at one month intervals The results were expressed in terms of adjusted odds ratios

  5. Results 7,807 households contacted (193 communications lost, 2%) 3,460 households participated (44.3%) Every member participated for 86% of these households 6,214 participants The present study concerned the 2,826 employed people

  6. Fig. 1. Distribution of the sample (n=6,214) and the Lorraine population (n=1,848,579 – Insee census) according to age (%)

  7. Table 1. Characteristics of the subjects (n = 2826): %

  8. Table 2. Demanding occupational hazards: %

  9. Fig. 2. Prevalence of psychotropic drug use (%)

  10. Table 3. Prevalence of psychotropic drug use according to age, sex, smoking habit and alcohol use: %

  11. Table 4. Psychotropic drug use for various job categories compared to executives, intellectual professionals, and teachers: OR adjusted on age and sex and 95% CI *p < 0.05, †p<0.01, ‡p<0.001

  12. Table 5. Relationship between the number of hazards NH and psychotropic drug use : 0R adjusted on age, sex and job and 95% CI

  13. Fig. 3. Relationship between the number of hazards NH and psychotropic drug use : 0R adjusted on age, sex and job and 95% CI 1.66 (1.26-2.20) 2.74 (1.83-4.09) 1.44 (1.15-1.75)

  14. Conclusions • Demanding work conditions may cause psychotropic drug use • Prevention should reduce occupational hazards, particularly when their number is high

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