5 Best Metabolic Health Solution Companies, 2023

December / Issue 07 / 2023

U processes that govern how our bodies convert food into energy, impacting everything from weight management to overall vitality. nderstanding metabolic health is paramount in a world where well-being takes center stage. Metabolic health encompasses the physiological Understanding the significance of metabolic health is not just a matter of awareness; it's a journey toward a healthier and more fulfilling life. Whether you are a healthcare professional, a researcher, or someone keen on optimizing your well-being, this edition of Insights Care has something valuable for everyone. Embrace the knowledge, embark on the journey to better health, and let the pages ahead be your guide in the pursuit of metabolic well-being. Metabolic Mastery Unearthed As we embark on this exploration, let's first demystify metabolic health. It's not merely about weight; it's a comprehensive assessment of how our bodies process nutrients, regulate blood sugar and maintain optimal functionality. Various factors, including genetics, lifestyle, and diet, influence metabolic health, making it a dynamic and personalized aspect of our well-being. Hope you have an informative read! The companies featured in this edition, '5 Best Metabolic Health Solution Companies, 2023,' are pivotal in reshaping the health and wellness landscape. They offer innovative solutions, from cutting-edge technologies to holistic approaches, addressing the nuances of metabolic health with precision. These companies aren't just providing remedies; they are at the forefront of a revolution, empowering individuals to take charge of their metabolic well-being. Managing Editor Managing Editor

CONTENTS Profiles Cover Story 24 20 08 Comite Center for Precision Medicine & Healthy Longevity biocrates Revolutionizing Health Assessment and the Future of Personalized Medicine Metabolic Mastery 32 Moritz Seuster CEO biocrates life sciences ag My Vital Metrics Visionary Approach Beyond the Scale Articles Transforma?ve Solu?ons 18 How a Metabolic Health Company is Changing Lives 28 A Holis?c Approach Smart Nutri?on for Metabolic Mastery

Editor-in-Chief Chidiebere Moses Ogbodo Managing Editor Pearl Shaw Executive Editor Natalie May Visualiser David King Art & Design Head Samuel Martinez Co-designer Paul Belin Art & Picture Editor Grace Brown Business Development Manager Emily Jones Marketing Manager Bill Thompson Business Development Executives Anna Smith, Jack Miller Sales Executives Mike, Carl, John Featuring Person Technical Consultants David, Robert Company Assistant Technical Head Joseph Taylor Technical Head Jacob Smile Brief Biocrates Life Sciences AG specializes in metabolomics solutions, offering innovative technologies and services for personalized medicine and research. biocrates life sciences ag biocrates.com Moritz Seuster CEO Digital Marketing Manager Assistant Digital Marketing Manager SME-SMO Executives Gemson Alina Sege Daniel Jones Comite Center for Precision Medicine & Health focuses on advancing precision medicine through comprehensive health assessments and personalized healthcare solutions. Comite Center for Precision Medicine & Health comitemd.com Dr. Florence Comite CEO & Founder Research Analyst Eric Smith Circulation Manager James Carter MDLifespan, offers health and wellness solutions, emphasizing longevity and quality of life through personalized strategies. MDLifespan mdlifespan.com Dr. Paul Savage Founder & CEO sales@insightscare.com December, 2023 Contact Us: Insights Success Media and Technology Pvt. Ltd. Survey No.133/134, Brand Square, Office No. 512, Kunjir Chowk, Pimple Saudagar, Pune, Maharashtra 411027. Phone - India: 7410033802, 8956487823 Email: info@insightscare.com For Subscription: www.insightscare.com My Vital Metrics provides health tracking tools and personalized insights through myvitalmetrics.com for individuals aiming to optimize their well-being. My Vital Metrics myvitalmetrics.com Owen Hutchins Founder Insights Success Media Tech LLC 555 Metro Place North, Suite 100, Dublin, OH 43017, United States Phone - +1614-602-4132 Email: info@insightscare.com For Subscription: www.insightscare.com Wondr Health is dedicated to enhancing well-being by providing personalized health and lifestyle solutions for individuals. Wondr Health wondrhealth.com Scott Paddock CEO https://twitter.com/Insightscare Follow us on : www.facebook.com/InsightsCare/ We are also available on : Copyright © 2023 Insights Success Media and Technology Pvt. Ltd., All rights reserved. The content and images used in this magazine should not be reproduced or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights success. Reprint rights remain solely with Insights Success Media and Technology Pvt. Ltd. Insights Care is powered by Insights Success Media and Technology Pvt. Ltd.

COVER STORY biocrates Revolutionizing Health Assessment and the Future of Personalized Medicine Moritz Seuster CEO biocrates life sciences ag

B revolutionary toolkit – the first of its kind – designed to measure and quantify metabolism in a standardized and quality-controlled manner. This cutting-edge technology is seamlessly integrated into liquid chromatography-mass spectrometry (LC-MS), unlocking new possibilities in diagnostics and the future of personalized medicine. iocrates is a trailblazing metabolomics technology company poised to reshape the landscape of health assessment. At its core, biocrates has crafted a Democratizing Metabolomics biocrates introduces a groundbreaking technology that democratizes access to metabolomics and amplifies knowledge dissemination. This inclusive approach caters to individuals already well-versed in LC-MS and metabolomics and those new to these domains. Through its innovative kits, biocrates has left its mark in thousands of peer-reviewed publications and has been embraced by numerous scientists spanning the realms of pharmaceuticals, academia, and healthcare institutions. As demand grows for richer health insights, CEOMoritz Seuster brings his dynamic leadership and extensive expertise to guide biocrates on its transformative journey. With LC-MS at the forefront, the company envisions a future where metabolomics becomes a cornerstone of everyday diagnostics and the evolution of “4P medicine” – a paradigm that prioritizes prediction, prevention, personal- ization, and participation in healthcare. Ready-to-Use Kits and Potential for Disease Manage- ment biocrates specializes in developing and producing ready-to- use kits that leverage LC-MS technology from globally renowned providers like Agilent, Sciex, Thermo Scientific, and Waters. These kits encompass both IP-protected hardware and cutting-edge software, providing scientists with a pragmatic means to expand their metabolomics biocrates doesn’t just analyze metabolites; it provides a deeper understanding of the complex mechanisms of health and disease. This knowledge paves the path for more accurate and individualized health assessments, laying the foundation for proactive health management. In a recent conversation with Moritz Seuster, Insights Care covered his journey along with these innovations and a brief overview of biocrates. Unveiling Health Complexity with Metabolomics In the past few decades, a significant portion of attention within modern medicine and drug development has been directed toward genetics. Proficiency in the field of biochemistry, once a favored toolkit for recent generations of researchers, general practitioners, and lab doctors, has somewhat diminished. However, it’s crucial to recognize that factors beyond genetics, such as lifestyle choices encompassing diet, stress, and more, wield a substantial impact on health. These factors extend beyond genetic predisposition and hold the key to unraveling the origins of numerous chronic diseases. biocrates builds the tools needed for sustainable and accessible healthcare and biomedical research. When delving into diseases like cancer and diabetes, looking beyond genetics to the role of lifestyle becomes imperative. This requires a more comprehensive and dynamic assessment of the current status of various molecules within an individual’s body. This is where metabolomics offers insight into this intricate web of influences.

5 Best Metabolic Health Solution Companies, 2023 research efforts. The company sees these kits as efficient tools for everyday health monitoring. The kits have the potential to identify metabolic imbalances at the early stages of disease, thus enhancing treatment outcomes This cohesive blend of mission, values, and accessible solutions underscores biocrates’ commitment to driving progress in the field of metabolomics and its far-reaching impact on healthcare and research. . Empowering Through Technology In academic research and pharmaceutical development, metabolomics has proven to be a valuable asset. By advancing understanding of mechanisms of disease, biocrates’ offerings are already contributing to better disease management and treatment optimization. biocrates’ management views its kits as the definitive benchmark in quantitative metabolomics. Its software is hosted on the cloud and boasts a fully integrated workflow system so that users can quantify, validate, and interpret their data securely and efficiently. Enabling Accessible Progress biocrates’ mission centers on sustainable health, under- pinned by the goal of making metabolomics accessible to facilitate breakthroughs in biomedical research. This accessibility extends throughout the entire user experience: purchasing high-end products through a user-friendly webshop, integrating the technology into trusted labs, conducting measurements and analytics via intuitive workflow software, and benefiting from a supportive community when interpreting data. It is an approach that appeals to participants from diverse sectors such as reference labs, pharmaceutical companies, biotech startups, academia, and governmental health organizations. An innovative leap has been taken in integrating data- driven artificial intelligence (AI) into biocrates’ processes. This accelerates data analysis, allowing users to channel their focus toward interpretation. With a commitment to data privacy and GDPR compliance, users maintain complete ownership of their information. This synthesis of cutting-edge technology, user-centric design, and data security underscores the company’s dedication to providing top-tier solutions for quantitative metabolomics. Vision and Strategic Focus A significant transformation in the field of science lies in the quick adoption of novel approaches. Technologies like genomics and proteomics are some of the most valuable approaches to biomedical research. However, they often fall short of identifying consequences at the functional level. Metabolomics unlocks this black box and gives the industry access to what truly transpires within the human body. For this reason, biocrates firmly believes that metabolomics is poised to bring the missing pieces to the puzzle, both as a stand-alone technology and in combination with other omics. Through their phenotyping expertise and products, biocrates assists scientists and practitioners in uncovering fresh insights concerning disease prevention, personalized health, and overall well-being. The company’s foundation rests on four core values: Purpose: Collaboratively with partners and customers, biocrates translates metabolic knowledge into tangible improvements in patient health on a day-to-day basis. Community: The company highly values collaboration, reliability, and authenticity. By standardizing metabolomics, it creates a space for innovative ideas, diverse perspectives, and groundbreaking concepts within the community, fostering progress in modern medicine. Currently, three areas are central to biocrates’ strategic focus: Cutting-edge software: The company's primary objective centers on capitalizing on its novel AI-based software environment. This unique tool enables the scientific community to draw insights from data that would have previously been overlooked. Ownership: biocrates actively listens to feedback from customers, colleagues, and partners, shaping its products and initiatives accordingly. Excellence: Rooted in curiosity, the company embraces challenges and continually develops expertise, recognizing that this is crucial for delivering high-quality outcomes and personal growth. Expanding quantitative coverage: Broadening the spectrum of quantifiable metabolites is a major step forward. This expansion is particularly crucial for health tech entrepre- neurs, pharma researchers, the nutrition industry, and academia. Over the past decade, biocrates has escalated its

quantification capacity from a few dozen to over a thousand metabolites, and this number continues to grow. Collaborat- ing closely with the metabolomics community, biocrates is identifying pertinent molecules for research and drug development. The objective is to continually enhance the quality of results through the inclusion of these relevant molecules in quantitative kits. Improving consumer health: A profound shift is underway in how individuals approach their health. Rather than waiting for illness, there’s a growing desire to understand one’s body long before disease strikes. Traditional diagnostics often lack a preventive or predictive component, leaving people to seek answers elsewhere. biocrates believes that quantitative metabolomics offers a robust solution. Unlike the superficial analyses prevalent in many consumer test offerings, quantitative metabolomics provides a comprehensive, scientifically rooted approach. The company’s focus rests on assisting laboratories in generat- ing meaningful data and insights on metabolic changes before diseases manifest. Standardized blood, feces, and urine analyses empower laboratories to scale their capaci- ties and aid general practitioners in understanding patients’ metabolic profiles, enabling disease prevention. Improving consumer health: unlike the super?icial analyses prevalent in many consumer test offerings, quantitative metabolomics provides a comprehensive, scienti?ically rooted approach. biocrates considers that the industry can gain insights into the true unfolding of processes through metabolomics, marking a significant stride toward comprehensive knowledge and transformative impact. Data-Driven Approach and Collaborative Initiatives biocrates is encouraging its clientele to broaden their data reservoirs with metabolomics technology that has demonstrated consistency and comparability for over a decade. The goal is to help customers extract meaningful insights and collaborate in shared learning. This endeavor culminates in the formation of the new quantitative metabolomics database, a repository of reference ranges for healthy subjects that draws upon thousands of data points. These reference ranges are akin to the clinical chemistry benchmarks provided by general practitioners, but they are derived from a significantly larger dataset.

ensuring the seamless integration of this technology into lab infrastructure. Technical support is readily provided as needed. Notably, biocrates’ technology is not restricted to a specific disease, offering applicability across a spectrum of diseases and employing a wide array of biological materials—ranging from blood, plasma, urine, and feces to organ tissue—throughout various stages of investigation, with particular promise for early asymptomatic disease stages. biocrates democratizes metabolomics, making it accessbile to a wider spectrum of users for therapeutic monitoring, disease screening, and more. A defining characteristic of biocrates’ technology is its capacity to generate rapid insights applicable to multi-disease approaches, including the influence of the microbiome. Metabolomics’ unique capability to unveil the common origins of multiple chronic diseases underscores its potential for a wide-ranging impact. To learn more about biocrates, please visit https://biocrates.com In addition, biocrates democratizes metabolomics, making it accessbile to a wider spectrum of users for therapeutic monitoring, disease screening, and more. A pronounced focus is placed on customers with a priority on scalability and the consistency of longitudinal data. This concerted effort has led to a diverse customer base spanning academia, pharmaceuticals, contract research organizations (CROs), biobanks, and routine laboratories across key global regions. Driven by the mission to make metabolomics accessible, biocrates extends its services through a certified laboratory program. This program is designed to expand the reach of metabolomics service measurements. Currently, a network of 12 seasoned laboratories spanning Europe and North America collaborates with biocrates to meet and scale the burgeoning demand for metabolomics services. Whether the interaction with customers is direct or intermediated through partners, biocrates is steadfast in

Transformative Solutions Metabolic Metabolic How a Health Company Health Company Changing Lives Changing Lives is ave you ever wondered if there's more you could H health company is dedicated to helping you optimize your health in a sustainable, lifelong way. By evaluating your biomarkers and crafting a customized plan focused on nutrition, exercise, sleep, and stress management, they provide the guidance and accountability you need to make meaningful changes. A metabolic health company focuses on identifying and addressing the root causes of these issues through personalized solutions. They go beyond a one-size-fits-all approach to provide customized programs based on your unique biology and lifestyle. be doing for your health and wellness but felt overwhelmed by all the options? A metabolic Symptoms and Root Causes of Metabolic Dysfunction Metabolic dysfunction can manifest itself in many ways. The symptoms are varied but the underlying causes often stem from similar root issues. Take your wellness into your own hands and see what you're truly capable of with the right support and strategies. A new, healthier you is within your reach. Chronic Fatigue Understanding Metabolic Health and Why It Matters Feeling constantly drained and low on energy are common complaints. Simple tasks seem to require a huge effort. This can be a sign your cells aren't producing enough energy. Understanding your metabolic health is crucial to transforming your life and overall well-being. Your metabolic rate refers to all the chemical reactions in your body that convert the food you eat into the energy you need to power everything you do. When your metabolism is balanced and efficient, you have metabolic health. Some signs you may have metabolic health issues include: Stubborn Weight Gain If losing weight is an ongoing struggle, your metabolism may be sluggish. Hormone imbalances and inflammation are frequent contributors. Getting the right nutrition and restorative sleep are key. Digestive Problems Difficulty losing weight or frequent weight gain. Low energy or chronic fatigue. High blood pressure or cholesterol. Insulin resistance or prediabetes. Sleep problems or mood changes. Ÿ Ÿ Ÿ Ÿ Ÿ Bloating, constipation, diarrhea and stomach pain can all point to problems with your gut health and microbiome. An imbalance in gut bacteria or issues like leaky gut syndrome impairs your ability to properly digest food and absorb nutrients. 18 19 www.insightscare.com www.insightscare.com December 2023 December 2023

Sleep Issues Lifestyle and Exercise Suggestions Difficulty falling or staying asleep, restless sleep and waking up still feeling tired are signs your circadian rhythm and sleep-wake cycle may be disrupted. Optimizing sleep hygiene and managing stress levels can help. In addition to nutrition, metabolic health companies evaluate how other lifestyle factors like sleep, stress and physical activity influence your wellness. Based on your test results and goals, they provide practical tips for improving sleep hygiene, managing stress, and the types of exercise that will be most effective for you. Whether walking, yoga, high intensity interval training or strength training, they can guide you to the activities that will yield the biggest benefits. Mood Changes Feeling irritable, anxious or depressed can arise from metabolic dysfunction. Nutrient deficiencies, hormonal imbalances and high inflammation are commonly linked. Correcting these root causes may help support better mood and mental well-being. Conclusion You owe it to yourself to take control of your health and make positive changes to feel your best. A metabolic health company provides the tools and support to help overhaul your wellness from the inside out. Their innovative tests and personalized programs are tailored to your unique biology and lifestyle. By gaining insight into how your body really works, you'll be empowered to optimize your health in a sustainable way. The good news is there are solutions. Working with a metabolic health expert, you can address the underlying drivers through personalized nutrition plans, supplements, lifestyle changes and cutting-edge therapies. How Metabolic Health Companies are transforming lives Partnering with experts in the field of functional and integrative medicine is an investment in yourself that will pay dividends for years to come. The future is yours to shape; now, go out there and create the healthy, vibrant life you deserve! Metabolic health companies are transforming lives by providing personalized solutions to improve wellness. Rather than a one-size-fits-all approach, these companies analyze your unique biomarkers and genetics to create customized plans for optimal health. Personalized Nutrition Plans -Natalie?May Based on blood tests and DNA analysis, metabolic health companies can determine your nutritional deficiencies and needs. They will then create meal plans tailored to your body's requirements. Whether you need to lose weight, gain muscle, reduce inflammation or boost energy, an individualized nutrition plan can help you achieve your goals. Targeted Supplement Recommendations Many people take supplements but don't know if they actually need them or are taking the right forms and dosages. Metabolic health companies test how your body metabolizes and absorbs nutrients to determine what supplements you may benefit from, such as certain vitamins, minerals, probiotics or botanicals. They can then provide recommendations for high-quality supplements in the proper amounts based on your test results. 20 www.insightscare.com December 2023

5 Best Metabolic Health Solu?on Companies, 2023 Comite Comite Center for Precision Medicine & Healthy Longevity Metabolic Mastery Interest in longevity, extending lifespan, is booming, but while I love the word "longevity," I prefer "healthy longevity." At the Center we are driven to not only help people live longer but to help them live longer in optimal health. To me, it is about achieving a healthspan that matches our lifespan. What inspired you to establish the Center and how has it evolved since then? Having an identical twin allowed me to innately recognize that despite the similarities, there are significant differences between my sister and me. The genes we inherit play a role, yet genetic expression is key. That allowed me a leap of faith to recognize that all of us are unique. Yet clinical studies that look at thousands of people, hoping to find significance, are flawed. One size does not fit all. The very essence of what makes each of us unique demands that we look at people individually to see how they differ and evolve over time and then assess their response to any intervention, whether it's sleep, food, exercise, supplements, medications, or habit change. H Individuals worldwide are increasingly seeking ways to not just treat ailments but to enhance their health, focusing on nutrition, supplements, and holistic lifestyle choices. Amidst this transformative era, the Comite Center for Precision Medicine & Healthy Longevity, situated in the center of Midtown Manhattan, stands as an institution of innovation and excellence. Dr. Comite, could you share a bit about your professional journey and what inspired you to become a clinician-scientist in the field of precision medicine? ealthcare is witnessing a paradigm shift—one that embraces a proactive approach to well-being, transcending the traditional reactive model. When I graduated from Yale School of Medicine, my father said to me, "OK, my doctor daughter, now, tell me how I can make myself healthier." My father kept himself in good shape all his life, but he wanted to know more about how he could extend his healthy years. Honestly, I couldn't answer him. In medical school, we weren't taught how to prevent disease related to aging, getting older and weaker. My father wanted to stay strong and healthy, without declining, and live long. He loved life. In medical school, we are taught to diagnose symptoms and concerns to treat them—to find the etiology of the patient's "chief complaint" and then fix the problem. My father's question triggered an insatiable curiosity in me about finding ways to keep our health despite aging and disease. Why do we have to wait for symptoms to emerge? That's reactive medicine. Why aren't we proactive to prevent disease from occurring in the first place? As I continued in my career as a clinical research scientist at the National Institutes of Health and then on the Yale faculty in academia and private practice, I sought to identify early signs of disease brewing at the cellular level, identify patterns that predict future disease, and develop strategies that ultimately reverse biological aging because aging is the trigger for chronic disease. The Center has evolved every year as we delve deeper and accumulate data about each of our clients. (We prefer to call them "clients," not "patients," because the latter suggests they are sick.) From a physical standpoint, our main office moved to a larger location to Central Park South in New York City over 5 years ago. Then, during the pandemic, I established satellite offices in Palo Alto, CA, and Miami Beach, to serve my growing clientele. In 2023, I launched the virtual GROQ Health app to scale precision medicine for healthy longevity that would be accessible, financially reachable, and available to everyone through a digital platform. GROQ Health ( https://www.groqhealth.com/ currently offered to businesses as an employee health benefit. In 2024, we will expand to offer the app direct to consumers starting with the thousands who have reached out and joined our waitlist. Leading this innovative establishment is Florence Comite, MD, a distinguished physician-scientist and the visionary founder of the Comite Center. Recognized globally for her groundbreaking work in precision medicine, Dr. Comite has dedicated her career to pushing the boundaries of healthcare, leveraging N-of-1 data to detect, predict, and reverse age-related disorders, thereby optimizing health and vitality. Florence Comite, MD CEO & Founder Comite Center for Precision Medicine & Healthy Longevity ) is Established in 2005, the Comite Center is at the forefront of personalized precision healthcare. Dr. Comite's unique and clinically proven approach, structured as a living clinical trial, sets the center apart. It offers a proactive and modern methodology for characterizing health trajectories, optimizing healthspans, and mitigating health risks. At the Center we are driven to not only to help people live longer but to help them live longer in optimal health. How has your personal journey influenced your dedication to advancing the field and ensuring its accessibility to a global audience? Dr. Comite believes in the potential of precision medicine to enable humans to live up to 150 years while maintaining optimal health. Could you provide an overview of the Comite Center for Precision Medicine & Healthy Longevity and its mission? Every day, I see the promise of precision medicine to help my clients reverse aging and attain optimal health. Over the past 20 years, thousands of women and men have benefited from the Center. I'm delighted that our success is now being independently verified through OMICm Age, a phenotypically trained epigenetic methylation algorithm at the certified independent testing lab Currently, five of my clients appear among the top 20 In an exclusive interview, our team had the privilege of engaging with Dr. Comite to dig deeper into her vision for metabolic health and how the 'Comite Center for Precision Medicine & Healthy Longevity and her new app Groq Health will add years to millions of lives.' The Comite Center for Precision Medicine & Healthy Longevity is a bespoke medical practice providing highly personalized healthcare structured as an trial of a single client. Our mission is to reverse aging in our clients to stop and prevent chronic diseases driven by aging. ™, a clinical Nof1 TruDiagnostic . 24 25 www.insightscare.com www.insightscare.com December 2023 December 2023

people reversing biological age on the Rejuvenation Olympics. In my own life, I've witnessed the power of looking at the human body on the cellular level to improve health span through targeted interventions driven by precise data. Each human deserves access to the wisdom that virtual GROQ Health offers to own their health destiny to stop future disease and live life to the fullest. In-depth Analysis In-depth Analysis of Client Outcomes of Client Outcomes Body Fat Loss: 98% of male clients and 87% of female clients at the Center have successfully shed body fat. How does the Center integrate and interpret genomic, metabolomic, phenotypic, and digital health data to provide predictive analysis and actionable guidance for individual patients? Visceral Abdominal Fat Reduc?on: We begin with our Precision Health Analysis™, a comprehensive investigation of biomarkers that provide thousands of data points, which allows us to connect-the- dots, identify trends, and predict a client's health trajectory. By integrating and interpreting the data, we determine the most appropriate interventions to extend health span to match lifespan. Body composi?on analysis reveals a significant decrease in visceral abdominal fat, observed in 97% of men and 90% of women. Muscle Mass Increase: Remarkably, 92% of male clients and 56% of female clients have experienced a notable rise in muscle mass. What challenges have you encountered in promoting and implementing precision medicine on a global scale? Improved Sleep: The greatest challenge in scaling precision medicine has been in condensing a medical protocol of many disparate yet connected biomarkers and data points into a simpler, hyper-focused program with accessibility on the small screen of a smartphone. A posi?ve impact on sleep quality is reported by 81% of male clients and an impressive 92% of female clients. Enhanced Energy Levels: What do you see as the future of precision medicine, and how does the Comite Center for Precision Medicine plan to stay at the forefront of innovation? Noteworthy improvements in energy levels are seen in 83% of male clients and 86% of female clients. Precision medicine will see exponential growth in the next decade as consumers recognize that our current reactive healthcare system is failing to prevent the chronic diseases of aging—diabetes, heart disease, obesity, cancer, and more. Costs are rising, yet outcomes aren't improving, especially among our aging population. More consumers than ever before want to take greater personal control of their health. Our GROQ Health app is a tool that allows each person to understand what's happening in their body on the cellular level and take steps to reverse biological aging and keep their health for life. The GROQ Health app is poised to bring that level of D-I-Y to their fingertips through the personal guidance of top clinicians and greater than 20 years of successful clinical outcomes. Increased Endurance: Significant enhancements in endurance are observed, with 87% of male clients and 69% of female clients repor?ng posi?ve changes. 26 www.insightscare.com December 2023

A Holistic Approach Smart Smart Nutrition Metabolic Metabolic Mastery Mastery for O today's busy lives, we often prioritize convenience over our health. This can result in lifestyle diseases, potentially leading to more severe health issues. Recognizing the importance of smart nutrition can contribute to maintaining a well-balanced and healthy lifestyle. ur food choices significantly impact our health. The saying "You are what you eat" perfectly highlights this connection. Unfortunately, in Let's break down the basics: 1. Balance Your Plate with Macronutrients Start by balancing your meals with the three musketeers of nutrition: carbohydrates, proteins, and fats. Carbs are your quick energy pals, and proteins help with muscle repair, and fats – yes, fats – play a role in hormone production. A harmonious mix ensures your energy levels stay steady throughout the day. This article will explore how adopting a simple yet thoughtful approach to our food choices can enhance our well-being and impact a healthier, more balanced life. 2. Quality Proteins for Strength Understanding Metabolism Proteins are like the superheroes of metabolism. They support muscle growth, aid in repair, and keep you feeling full. Opt for lean sources like chicken, fish, beans, and tofu to give your metabolism the protein punch it needs. Metabolism, often labeled the body's engine, governs the way we use and store energy. It's not a one-size-fits-all mechanism – it varies based on factors like age, genetics, and lifestyle choices. Imagine it like a gentle interplay between the processes of building up (anabolism) and breaking down (catabolism), both vital for our overall well- being. 3. Embrace Healthy Fats Don't shy away from fats – just pick the good ones. Avocados, seeds, nuts and olive oil are sources of healthy fats that support your brain, hormones, and the absorption of vitamins. It's all about nurturing your body, not depriving it. Smart Nutrition Smart nutrition isn't about complex diets or meticulous calorie counting. It's about making wise choices to fuel your body efficiently. It involves making informed and mindful choices about the food we eat to support overall well-being. 4. Champion Complex Carbs Ditch the simple sugars for complex carbohydrates found in whole grains, fruits, and vegetables. These provide a steady 28 29 www.insightscare.com www.insightscare.com December 2023 December 2023

stream of energy, keeping your metabolism humming along without the rollercoaster of blood sugar spikes. 2. Prioritize Quality Sleep Quality sleep is a metabolic game-changer. Lack of sleep messes with your hormones, making you hungrier and more prone to unhealthy cravings. Get 7-9 hours of quality sleep each night to boost your metabolism and overall health. 5. The Power of Hydration Water is not just for quenching your thirst. It's a metabolism ally involved in breaking down nutrients and flushing out waste. Aim for those eight glasses a day to keep your body's engine running smoothly. 3. Stress Less, Live More Chronic stress can throw a wrench into your metabolism. Adopt stress-reducing practices like meditation, yoga, or deep breathing. Your body will thank you, and your metabolism will operate more smoothly. 6. Mindful Eating: Listen to Your Body Mindful eating is a game-changer. It involves savoring each bite, recognizing when you're full, and avoiding distractions during meals. This practice advances a healthy relationship with food and prevents overeating – a win-win for your metabolism. Your Metabolic Journey As we navigate the complexities of modern life, let's not overlook the simple yet profound impact of smart nutrition on metabolic mastery. It's not about rigid diets or complicated formulas. It's about making conscious, informed choices that nourish your body, mind, and soul. 7. Meal Timing Matters Spread your meals throughout the day like a well- orchestrated symphony. Consistent meal timing regulates blood sugar levels, preventing those energy crashes. Remember, your body loves routine, and it rewards you with efficient metabolic processes. Embrace the balance of macronutrients, choose quality proteins and fats, savor the goodness of complex carbs, and stay hydrated. Listen to your body, adopt a personalized approach, and complement your nutritional choices with an active, balanced lifestyle. 8. Personalize Your Approach Your metabolism is as unique as your fingerprint. Age, genetics, and health conditions play a role. Consider seeing a nutritionist for a personalized plan. This ensures your journey towards metabolic mastery is tailored to your individual needs and goals. -Natalie?May Lifestyle Factors Smart nutrition is not a solo act. Lifestyle factors play a critical role in achieving metabolic mastery. 1. Exercise Regularly Move that body! Exercise is not only reducing calories but also reducing insulin sensitivity and boosting your metabolism. Combine it with cardio, strength training, and flexibility exercises for a comprehensive health improvement. 30 www.insightscare.com December 2023

5 Best Metabolic Health Solu?on Companies, 2023 moved into sports therapy and personal training. I did the very usual personal training grind at one of the big commercial gyms for several years. I always felt it was incredibly challenging to really hone in on the exact results that we were getting for our clients. The theory is that we want them to potentially lose fat gain muscle or at least avoid losing muscle and gaining fat, but the data that was available only gave us and so we were not able to accurately pinpoint exactly what effects the training was having for the client. I eventually left the Personal training industry and focused on working as a sports therapist part- time whilst pursuing other career paths in project management and change management. 2014 to 16 I also did my MBA, and that led me to really want to start a business of my own. Visionary Approach Beyond the Scale I that weight alone defines well-being. Explore a world where holistic health is decoded through vital metrics, revealing a comprehensive understanding of your body's intricate balance. n a world where health is often measured by numbers on a scale, My Vital Metrics takes a revolutionary leap, challenging the notion How would you describe the core mission and values of My Vital Metrics? more kit. We have added a functional movement assessment which assesses and measures how well people are moving through all of the main joint complexes. We also added some simple blood testing for Hba1c which is a historical record of blood sugar and a lipid profile, which is your standard cholesterol tests and fractions. My Vital Metrics' core mission is to bring scientific grade testing to the general public and to improve their understanding of their own bodies and how to get fitter, get healthier, live longer, happier, lives and achieve their aesthetic goals. Founder Owen Hutchins, a seasoned figure in the health and fitness industries, recognized the limitations of conventional assessments during his early days as a personal trainer in the late '90s. Back then, the pinch test was the go-to method for evaluating body fat. Fast forward 18 years, and Owen's relentless pursuit of knowledge led him to the transformative power of regular DEXA scans, offering unparalleled insights into internal changes. Can you elaborate on the seamless service that My Vital Metrics aims to provide? How does this set the company apart from other health and fitness solutions? How has the company evolved since its inception just before the COVID-19 pandemic, and what services does My Vital Metrics currently offer? We aim to provide the most comprehensive set of tests from composition to metabolic to blood and strengthen movement tests all under one roof. There is no other facility currently in the UK which offers the same breadth of tests that we offer. With all this testing, however, our key focus is on selecting tests or scans from which Client can take practical steps to improve the measure, and those practical steps and improvement of the measure will vastly improve their lives. Throughout the pandemic, our service offering necessarily had to stay the same. We opened our doors for the first time in January 2020, and then of course we had to close in April for the first lockdown. This meant that the first two years of the business were deeply affected by the pandemic as the very essence of the work that we do is that it is all in person. Since September 2021, however, we moved to a slightly larger location, and this enabled us to get some With a foundation rooted in sports therapy training in Australia, Owen has been an influential presence in health and fitness for over two decades. My Vital Metrics, the brainchild of this visionary entrepreneur, specializes in scientific assessments tailored for individuals on a journey to enhance their health and performance. Can you highlight some of the key milestones and achievements of My Vital Metrics that you are particularly proud of? Owen Hutchins In an exclusive interview with Insights Care, Owen delves into the unique attributes that set My Vital Metrics apart from the other metabolic health solution companies. We aim to provide the most comprehensive set of tests from composi?on to metabolic to blood and strengthen movement tests all under one roof. Honestly, our biggest achievement in a way was simply to still be here, despite some very unfortunate timing of the pandemic and the lockdowns and the lack of business that led to. We are, however, incredibly proud to be able to bring this set of tests to the general public and make them accessible. We are also proud to be able to work with a number of top sports teams and athletes. When we came into this business, we assumed that professional athletes Can you share a bit about your journey in the fitness industry and how it led to the establishment of My Vital Metrics? I did my initial training in Australia as a sports therapist, and then came over to the UK and Founder My Vital Metrics 32 33 www.insightscare.com www.insightscare.com December 2023 December 2023

already had access to these tests as there was so much literature on how important they were in particular to the athlete. What has emerged however is that many athletes do not have access to the kind of test and equipment that we do and so we are incredibly proud to be able to help and supply services to the professional sports community as well allowing them to take a more scientifically rigorous approach to their performance. What does it mean for My Vital Metrics to be recognized as one of the Best Metabolic Health Solution Companies in 2023? It means a great deal to be recognized as one of the best metabolic health solution companies in 2023. 2023 has been a huge year for this kind of testing when you have the likes of Dr Peter Attia and Dr Andrew Huberman, talking about the importance of testing all the time. There has been a real upsurge in interest in personalizing fitness and health plans for longer life, and for making the most out of the life we have. And it is very gratifying to know that we have been doing these tests for the last couple of years and we are very pleased to meet the demand that came from this increased interest in these topics. What vision do you hold for the future of My Vital Metrics? The biggest thing for us is reach. Currently being situated in London very much limits the number of people we can give access to this testing so in the New Year we will be launching a mobile testing lab which will go all over the country, allowing people from every corner of the UK to get access to the testing that they want and to be able to take a more scientific and hopefully successful approach to their health and fitness goals. We are really excited for next year in My Vital Metrics and very much hope to cement our place as the best metabolic testing company in the UK. 34 www.insightscare.com December 2023

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5 Best Metabolic Health Solution Companies, 2023

5 Best Metabolic Health Solution Companies, 2023

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