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Translating Knowledge into Effective Action

Translating Knowledge into Effective Action. C. I N TR 2004. Annual Meeting Cairo October 2 nd –5 th. Mission Statement.

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Translating Knowledge into Effective Action

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  1. Translating Knowledge into Effective Action C INTR 2004 Annual Meeting Cairo October 2nd –5th Annual Meeting 2004

  2. Mission Statement The INCTR is dedicated to helping build capacity for cancer treatment and research in countries in which such capacity is presently limited ……and to increase the quantity and quality of cancer research throughout the world. Catalysis Concerted Effort Communication Sustainability Annual Meeting 2004

  3. The Problem High Mortality Rate Many Patients With Advanced Disease and Many Potential Patients Limited Resources Unmet need for Terminal Care LOW CAPACITY POOR ACCESS Annual Meeting 2004

  4. The Solution Education Screening Prevention Lower Mortality Rate Fewer Patients, with More Limited Disease and Fewer Potential Patients Less Limited Resources Terminal Care GREATER CAPACITY IMPROVED ACCESS Annual Meeting 2004

  5. The Goals • Prevent preventable cancers: • Focus presently on cervical cancer screening • Plan – include breast and oral cancer and provide education re: tobacco and poor habits • Cure curable cancers • Ensure presentation at earliest time • Focus on pediatric cancers, especially leukemias and lymphomas, retinoblastoma, Cx and breast cancer • Provide terminal care for those with no curative option Annual Meeting 2004

  6. The Strategy • Help build human capital through: • Promoting collaborative projects in prevention, and treatment which both help prevent and cure cancer, and provide education and training • Providing a variety of professional educational opportunities • Promoting relevant national and international research • Link research with delivery of care Annual Meeting 2004

  7. INCTR Funding/Resources • National Cancer Institute: Basic funds, support of educational programs via OIA • Corporations: partnerships, sponsorships • Institutions: Space, shared personnel, visiting experts, project development and conduct • Individuals: Associate Membership • Foundations and Grant-Giving bodies Annual Meeting 2004

  8. INCTR’s Network Annual Meeting 2004

  9. Offices and Branches • USA, UK, France, Brazil, Egypt, Tanzania, Saudi Arabia, India, Nepal • Regional/national coordination of INCTR programs and projects • Access to regional/national resources • Expansion of local capacity • Guiding principles : INCTR Charter Annual Meeting 2004

  10. Associate Membership • Corporate Membership (3) • Productive partnerships with the corporate world • Institutional/Organizational Membership (94) • Access to a broad range of expertise • Participation in INCTR activities • Individual Associate Membership (36) • Contributions, financially or in kind Annual Meeting 2004

  11. Corporate Partnerships • Eli Lilly • Annual unrestricted grant as a membership fee • INCTR provides off-site data management services in a randomized trial in locally advanced Cx cancer in 10 developing countries • Support of Clinical Trials Workshops • CTIS • Developed INCTR’s new Portal • Will provide internet-based clinical trials software Annual Meeting 2004

  12. Communications • NETWORK • INCTR Website • INCTR Portal • Telesynergy • Annual Meeting Annual Meeting 2004

  13. INCTR’s Website Annual Meeting 2004

  14. Newsletter Online Annual Meeting 2004

  15. INCTR’s Internet Portal Annual Meeting 2004

  16. Membership Form Online Annual Meeting 2004

  17. Telesynergy Meetings Annual Meeting 2004

  18. Project Development PROJECTS INCTR Programs, Committees, Branches, Associate Members Scientific Review Ethical Review Disease Specific Strategy Groups Implementation Annual Meeting 2004

  19. Active Projects (8) • Reasons for late presentation of retinoblastoma – 15 centers in 11 countries • Survey on breast cancer management - 4 countries (pilot) • Cx Cancer screening (with IARC) – 2 countries • Treatment of advanced cervical cancer (with Eli Lilly) – 10 centers in 10 countries • Treatment of metastatic osteosarcoma - 6 countries • Treatment and study of ALL in India - 4 centers + • Treatment and study of Burkitt’s Lymphoma in Africa - 5 centers in 4 countries • Provision of palliative care – Nepal (3 centers) Annual Meeting 2004

  20. Projects in Planning Phase • Treatment of locally advanced retinoblastoma • Treatment of locally advanced breast cancer • Treatment of locally advanced Cx cancer • Introduction of Cx cancer screening into the existing health-care structure – expanding population coverage Annual Meeting 2004

  21. Education • Clinical Trials Workshops (China, Brazil) • Pediatric Oncology Workshops (China, Dubai, Jordan/Irak) • Nursing Oncology Training (Cameroon, Algeria, Cairo) • Lymphoma Workshop (Cairo) • Program-specific training (training in molecular biology, Cx cancer screening, palliative care, establishment of cancer center in Kabul) Annual Meeting 2004

  22. Translational Research • Comparison of patterns of molecular subtypes of disease in different populations and environments (Indian leukemia) • Comparison of molecular patterns (DNA methylation, SNPs) in disease versus control populations • Training workshops for specific techniques Annual Meeting 2004

  23. Relevant Meetings and Expert Visits in Last Year Annual Meeting 2004

  24. Gutierrez MI, Siraj AK, Khaled H, Koon N, El-Rifai W, Bhatia K.CpG island methylation in Schistosoma- and non-Schistosoma-associated bladder cancer.Mod Pathol. 2004 Oct;17(10):1268-74 Siraj AK, Kamat S, Gutierrez MI, Banavali S, Timpson G, Sazawal S, Bhargava M, Advani S, Adde M, Magrath I, Bhatia K. Leukemia.Frequencies of the major subgroups of precursor B-cell acute lymphoblastic leukemia in Indian children differ from the West.Leukemia, 2003 Jun;17(6):1192-3. Publications in Medical Literature in 2004 • Book chapters: 4 • Original articles: 10 • In press: 2 • (Treatment of ALL in India, Lymphoma Workshop Report) Annual Meeting 2004

  25. Annual Meeting 2004 • Honoring outstanding contributions (Award lectures) • Individual presentations (posters, oral) • Reports on ongoing activities • Keynote lectures • Lectures on regionally important cancers • Consensus views on important topics – HDT with SC • Multidisciplinary conference – mediastinal HL • Workshops on cancer control • Forums and informal meetings Annual Meeting 2004

  26. Support • Office of International Affairs, NCI, Bethesda • National Cancer Institute, Cairo • Pharmaceutical sponsors: • Eli Lilly, Agfa-Gevaert, Astra Zeneca, Sanofi-synthelabo, Roche, Pierre Fabre, Janssen Cilag, Lipomed Annual Meeting 2004

  27. Participation Annual Meeting 2004

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