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History of the Dan L. Duncan Cancer Center

History of the Dan L. Duncan Cancer Center. Mission of the Dan L. Duncan Cancer Center. To prevent and ultimately cure cancer in all of its forms. To provide exceptional patient care To provide outstanding education for students

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History of the Dan L. Duncan Cancer Center

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  1. History of the Dan L. Duncan Cancer Center

  2. Mission of the Dan L. Duncan Cancer Center To prevent and ultimately cure cancer in all of its forms • To provide exceptional patient care • To provide outstanding education for students • To conduct innovative research into the causes, prevention and treatment of cancer • To provide community outreach and education, especially to the underserved

  3. Harris County Hospital District Hospital Partnerships and Patient Care Programs

  4. BCM Affiliates & Facilities BCM Clinic Rice Consortium Texas Children’s Hospital St. Luke’s Hospital Alkek Research Tower Baylor College of Medicine Ben Taub General Hospital Michael E. DeBakey VA Medical Center

  5. The Texas Medical Center RICE UNIVERSITY VAMC Parkwood

  6. Research Programs Cancer Biology Franko DeMayo, PhD Molecular Carcinogenesis Janet Butel, PhD Nuclear Receptors Orla Conneely, PhD Breast Cancer Dan Medina, PhD Cell and Gene Therapy Malcolm Brenner, MD, PhD Prostate Cancer Tim Thompson, PhD Cancer Prevention Powel Brown, MD, PhD Pediatric Cancer David Poplack, MD

  7. Membership and Grant Support Total members 270 NCI Grant Support ≈$ 40M Total Cancer Funding ≈$100M SPOREs 3 Program Projects 5 U01 Mouse Models 4 U54 2 U19 2 LLS SCOR 1 U01 Redes en Accion 1

  8. Developing ProgramWorking Groups Gastrointestinal Cancer Pancreas Cancer Lymphoma Melanoma Gene sequencing of human tumors

  9. Shared Resources

  10. Other Baylor Core Facilities • Bioinformatics Research Center • Blot Analysis • DNA Sequencing • Interdepartmental Deconvolution Microscope • Vector Development • Mouse Phenotyping

  11. Clinical Research • 4,000 new cancer patients diagnosed annually in partner hospitals • 40% minority; 55% female • 90 Investigator-initiated trials • NCI-funded cooperative group membership - SWOG - COG - NSABP - PBTC - ACOSOG - CALGB

  12. Bare-NS PEG-NS Anti-IL-13r-NS Live Dead Nanoshell Treatment of U373 Glioma Cells In press, Neuro-Oncology, 2007

  13. Future Plans of the DLDCC in Nanotechnology & Nanomedicine • Continue ongoing collaborations on nanotechnology projects with Rice and UT • High priority for ongoing/future research • Encourage faculty participation in the Keck Center Nanobiology Training program • Encourage trainees to participate in training programs/projects in nanotechnology • Commitment to space in the Rice Consortium building

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