1 / 2

Prof. Judit E. Puskas The Puskas group DMR #0509687 Program officer: Dr. Andrew J. Lovinger

Synthesis and Characterization of Novel Double-Functionalized Surface Modified Thermoplastic Elastomers. Prof. Judit E. Puskas The Puskas group DMR #0509687 Program officer: Dr. Andrew J. Lovinger. OH. OH. OH. OH. OH. OH. OH. OH.

kalli
Download Presentation

Prof. Judit E. Puskas The Puskas group DMR #0509687 Program officer: Dr. Andrew J. Lovinger

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Synthesis and Characterization of Novel Double-Functionalized Surface Modified Thermoplastic Elastomers Prof. Judit E. Puskas The Puskas group DMR #0509687 Program officer: Dr. Andrew J. Lovinger OH OH OH OH OH OH OH OH Dendritic (arborescent or tree-like) polyisobutylene-polystyrene block copolymers (arbIBS) are the third generation of polyisobutylene (PIB)-based nanostructured biomaterials. The first generation from this class of polymers, linear tri-block polystyrene-b-polyisobutylene-b-polystyrene (SIBS), is FDA-approved and currently used as the polymeric coating on drug-eluting coronary stents (http://www.taxus-stent.com/#, Device Details, Interactive Overview). XPS and AFM studies of SIBS and arbIBS biomaterials demonstrated that a 10 nm layer of pure PIB segregated to the surface during self-assembly of the nanostructure. Arborescent polyisobutylene has been synthesized by inimer-type living carbocationic polymerization of a newly synthesized inimer (initiator-monomer, IM), 4-(1,2-epoxy-isopropyl) styrene with isobutylene (IB) using TiCl4 as coinitiator. This IM yielded arbPIBs with Mn ~ 100,000 g/mol with 3-8 branches. Blocking of this material with polystyrene will yield arbIBS whose surface is decorated with –OH groups, further improving biocompatibility. OH OH OH OH OH OH OH OH OH OH OH OH OH OH OH OH Students: Elizabeth Foreman (US) Mustafa Sen (Turkey) Lyn Munoz Robledo (US) PDF: Kevin Cong (China)

  2. REU Program Outreach Activities Posters on the Hill 2006 Cortney L. Hoch The Puskas group DMR #0509687 Program officer: Dr. Andrew J. Lovinger International collaborators Supporters Polymer Engineering, Bayreuth, Germany (Rubber Division, Bayer Inc.) Puskas, Dr. Maden (Sen. Kennedy’s office), Hoch # 38895-AC7 Prof. Miroslawa El Fray Canada DFG Germany Technical University Szczecin, Poland Prof. Volker Altstädt Billi F.Copeland (Director, McNair Scholars), Hoch, Prof. Coleen Pugh (REU Director)

More Related