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September 9-13, 2007

Scientific Committee

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September 9-13, 2007

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  1. Scientific Committee N. Birdsall (UK), L. Brasili (Italy), D. Donati (Italy), G. Gaviraghi (Italy), M. Giannella (Italy), R. A. Glennon (USA), F. Gualtieri (Italy), R. Leurs (The Netherlands), C. Melchiorre (Italy), R. Pellicciari (Italy), G. Ronsisvalle (Italy), H. Timmerman (The Netherlands), D. J. Triggle (USA). Lunch and Refreshments Coffee and tea will be available throughout the meeting. Meals will be taken at the University restaurant (self-service). Travel Participants are requested to make their own travel arrangements. However, a free bus will be provided to connect Rome international airport (Leonardo da Vinci) with Camerino on Sunday September 9, 2007 (fill in the on-line application form). The bus will leave the airport at 2 p.m. Organizing Committee P. Angeli, M. Buccioni, F. Gentili, M. Giannella, D. Giardinà, G. Giorgioni, U. Gulini, G. Marucci, A. Piergentili, M. Pigini, W. Quaglia, G. Sagratini. 16th Camerino-Noordwijkerhout Symposium An Overview of Receptor Chemistry Accommodation Accommodation in the new University Residences is advised. Each room is provided with private bathroom. Details of prices are shown on the on-line application form (€ 50 deposit is required). Accommodation will also be possible in Camerino or nearby hotels, 5-15 km from the Symposium center (please visit the website for details). However, no bus service is planned and the use of one's own car is advised. Participants interested in hotel accommodation may contact the hotels directly. Dates and Location The 16th Camerino-Noordwijkerhout Symposium will be held in the “Sala della Muta” of the Palazzo Ducale - Camerino, from 9 to 13 September 2007. Symposium Bureau The Symposium bureau will be open from 2 p.m. to 8 p.m. on Sunday, 9 September 2007, and thereafter daily from 8 a.m. to 6 p.m. Deadlines to Remember April 30, 2007 Submission of Abstracts May 31, 2007 Early Registration May 31, 2007 Room Reservation Language The official language of the Symposium will be English. September 9-13, 2007 Correspondence Address Secretariat 16th Camerino-Noordwijkerhout Symposium Dipartimento di Scienze Chimiche Università di Camerino Via S. Agostino, 1 62032 Camerino, Italy Tel.: ++39 0737 402239/402237/402223 Fax: ++39 0737637345 e-mail: secretariat.camerino@unicam.it Scientific Communications The program includes one poster session. Posters will be subjected to a selection procedure. Abstracts have to be prepared using the on-line template (http://www.unicam.it/farmacia/symposium/Abstract07.doc) and e-mailed to abstract.camerino@unicam.it not later than April 30, 2007. Abstracts received by fax or mail will not be considered. Accepted communications will be copied directly into the abstract book. Notification of acceptance will be communicated to the author by June 2007. The scientific committee will select a number of abstracts for presentation as short oral communications. Participants wishing to accept such an invitation should indicate this on the application form. Camerino (Italy) Under the sponsorship of Medicinal Chemistry Division of the Italian Chemical Society (SCI) and European Federation of Medicinal Chemistry (EFMC) Further information and on-line registration and accommodation forms are available at: http://www.unicam.it/farmacia/symposium/index.html Second Circular European Federation of Medicinal Chemistry Medicinal Chemistry Division of Italian Chemical Society

  2. Scientific Program Registration Registration requests should be made on-line. All participants will receive acknowledgment of registration not later than July 31, 2007. The registration fee has been set for active participants and accompanying persons, respectively, at € 950 and € 450 before May 31, and at € 1150 and € 550 after May 31, 2007. Participants from academic institutions have the right to a € 150 discount on their enrollment fee. Members of the Italian Chemical Society have the right to an additional € 50 discount. The registration fee entitles participants to take part in conferences, social events, and all meals. The registration fee for accompanying persons entitles them to participate in social events, andall meals. The timetable of the social events will be communicated to the participants together with the final scientific program. Due to restrictions of space, it may be necessary to limit the number of those attending. Early registration is advised. All payments, net of bank expenses, have to be made: - by bank transfer to the Banca delle Marche, 62032 Camerino, BBAN: N 06055 68830 000000008287 in favor of “Receptor Chemistry - Dipartimento di Scienze Chimiche”, or - by banker’s draft in favor of “Receptor Chemistry - Dipartimento di Scienze Chimiche”. Neglected and Emerging Serotonin Receptors and Their Selective Ligands D. Donati (I) Recent Findings on 5HT6 Receptor Ligands - R. A. Glennon (USA); The 5-HT1F Receptor: Pharmacology, Physiology, and Structure Activity Relationships - D. L. Nelson (USA); New Templates for Serotoninergic 5-HT1A Receptor - D. Graziani (I); Selection and Evolution of a Lead Series During Its Optimisation: Novel Potent and Selective 5-HT2C Receptor Antagonists - D. Hamprecht (I) . Opening: Multifunctional Drugs – C.Melchiorre (I) Drug Targets: Finding and Validating Them D. J. Triggle (USA) The Druggable Genome – A. L. Hopkins (UK); Chemical Biology & Target Search – R. C. Flaumenhaft (USA); Chemical and Biological Descriptor Space: what Can We Learn from a Systematic Comparison? R. V. Stanton (USA). alpha-Adrenoceptors: What Progress Has Been Made? R. A. Glennon (USA) Molecular Pharmacology of alpha2-Adrenoceptor Subtypes - M. Scheinin (FI); alpha-2-Adrenoceptor Agents in the Modulation of Pain - M. Dukat (USA). WNT Pathway M. Giannella (I) High Throughput Virtual Screening in Modern Drug Discovery – A. Padova (I); Hedgehog Receptors – Modeling Based Approaches for Cancer Research - G. Robertson (I); The Wnt Pathway – Phenotype Screening Approaches to the Treatment of Neurodegenerative Diseases – G. Gaviraghi (I). Development of Chemokine Receptor Antagonists R. Leurs (NL) Chemokine Receptor Antagonists: What Next? - R. Horuk (USA); CCR5 Antagonists for the Treatment of HIV - D. Pryde (UK); Small Molecule Antagonists of the CXCR2 Chemokine Receptor - J. Wijkmans (NL); Development of Chemokine Receptor Modulators - M. Allegretti (I) Deorphanized Receptors R. Ciccocioppo (I) Orphan GPCRs and the Search for New Neurotransmitters and Their Functions - O. Civelli (USA); Structure Activity Studies on Neuropeptide S - G. Calò (I). New Aspects on GPCRs G. Marucci (I) Molecular Mechanisms of Agonist-Induced Activation of GPCRs - L. Pardo (E); Molecular Basis of GPCR Function - J. Wess (USA); Allosterism at GPCRs: from Ligands to Drugs? - N. Birdsall (UK); Molecular Mechanisms of Inverse Agonism at GPCRs - T. Costa (I); Mechanisms of Agonist Efficacy at GPCRs - P. G. Strange (UK); Probing Structural Rearrangement within Receptor/G Protein Complexes Using BRET Technology - C. Gales (F). Nuclear Receptors L Mosti (I) Modulators for the Farnesoid X Receptor (FXR): from Bench to Therapeutic Exploitations - R. Pellicciari (I); Identification and Characterization of Highly Potent Activators of the Nurr1 (NR4A2) Pathway - a Novel Approach to Treat Parkinson Disease?- S. Hintermann (CH); Blockade of PPAR-Gamma - W. J. Hoekstra (USA); Potent and Balanced Dual PPAR Alpha/Gamma Agonists: Combining Antidiabetic and Hypolipidemic Activity - U. M. Grether (CH). Refunds Upon cancellation before August 1, 2007, 80% of the fee will be refunded. After August 1, no refund will be possible. Pain Treatment Development G. Ronsisvalle (I) The Endogenous Cannabinoids: New Major Players in Physiology - R. Mechoulam (IL); When Chemistry Mimics Physics. The Manipulation of TRP-V1 and Related Ion Channels by Small Molecules - G. Appendino (I); Chemical and Functional Bridges between Two Chemically Different but Functionally Related Types of Receptors: TRP Channels and Cannabinoid Receptors - V. Di Marzo (I); Recent Findings on Imidazoline Receptors - A. Hudson (CDN); Most Recent Findings on Sigma Ligands - J. Holenz (E). Note The Medicinal Chemistry Division has awarded 2 free grants (enrollment fee, and lodging in the University Residences) for Ph.D. research students in Medicinal Chemistry who are members of the Italian Chemical Society. Those interested should send to the Secretariat not later than April 30, 2007 a CV giving their graduation marks, the title of their dissertation, and current field of research. In the event that the requests to participate should exceed this number, then an integrative fee will have to be paid. Future Drugs For Neurodegenerative Diseases Treatment H. Timmerman (NL) Purinergic Receptors and Neuroprotection - G. Cristalli (I); Aporphinoids as Building Blocks for Dopaminergic Agents - J. Neumeyer (USA); Histamine H3 Receptor Ligands - I. J. P. De Esch (NL). Summing up D. J. Triggle (USA).

  3. The use of one own’s car is advised Other Camerino Hotels/Country Houses Agriturismo Le Arcate di S. Angelo Loc. Morrone 62032 Camerino Tel: +39-339-8852761 Casa Per Vacanze Villa Maria Via G. Di Giovanni, 41 62032 Camerino Tel: +39-335-5868697 Casa Per Vacanze Largo Valentini L.go Valentini, 4 62032 Camerino Tel & Fax: +39-0737-630232 Casa Per Vacanze Ja. Le. Via Conti Di Borgo, 83 62032 Camerino Tel: +39-0737-630287 Fax: +39-0737-46157 Casa Per Vacanze I Girasoli Loc. S. Marcello, 24 62032 Camerino Tel: +39-0737-632740 Mobile: +39-335-7503752 Country House Pappafo’ Loc. Montagnano, 98 62032 Camerino Tel: +39-0737-630794 Fax: +39-0737-631336 B&B Poggio Maria Loc. Agnano, 1 62032 Camerino Tel: +39-0737-644318 Mobile: +39-338-8616850 B&B Fabris Bruna Loc. Rocca Varano 62032 Camerino Tel: +39-0737-630488 Albergo Borgo di Lanciano**** Loc. Lanciano, 5 62022 Castelraimondo Tel: +39-0737-642844 Fax: +39-0737-642845 Albergo Al Borgo Antico*** Fraz. Morro p.zza Macallè, 3 62032 Camerino Tel: +39-0737- 637597 Mobile: 335-7248806 Albergo Il Cavaliere *** Via Mariani 33-35 Loc. Polverina 62032 Camerino Tel: +39-0737- 46128 Fax: +39-0737-46129 Albergo Roma ** P.zza Garibaldi, 6 62032 Camerino Tel: +39-0737-630125 Fax: +39-0737-632592 Albergo del Sole ** Via Mariani, 59 Loc. Polverina 62032 Camerino Tel: +39-0737- 46115 Fax: +39-0737-46167 Hotel Massi*** Via A. Merloni 62024 Matelica Tel. +39 073784781 Fax +39 073785981 Hotel Bellavista*** Via S. Anna, 11 62022 Castelraimondo Tel. +39 0737640717 Fax +39 0737642110 Motel Carnevali*** Bivio Maddalena S.S. 77 62034 Muccia Tel. +39 0737646138 Fax +39 0737646428 Albergo Il Cacciatore*** Via Spinabello, 13 62034 Muccia Tel. +39 0737646121 Fax. +39 0737647002 Hotel della Loggia*** P.za E. Mattei, 12 62024 Matelica Tel. +39 073785830 Fax +39 0737787239 Hotel Panorama*** via Del Colle, 5 Loc. Crispiero,62022 Castelraimondo Tel: +39-0737-642642 Agriturismo La Cavallina Fraz. Polverina Via Mariani, 13 62032 Camerino Tel: +39-0737-46173 Fax: +39-0737-464500 Agriturismo Le Cortine Via D’Accorso, 75 Loc. S. Paolo 62032 Camerino Tel: 0737-616840 Mobile: +39-333-2237294 Agriturismo Dragoncello Loc. Servola, 5 62032 Camerino Tel: 0737-637184 Mobile: +39-333-1773059 B&B Palazzetto Giochi Loc. Casale Di Morro 62032 Camerino Tel: +39-0733-35929 Mobile: +39-347-3336460 B&B Marggraf Mary C. Loc. Costa S. Severo, 8 62032 Camerino Tel: +39-0737-42302 Fax: +39-0737-631114 B&B Caselunghe Loc. Caselunghe, 2 62032 Camerino Tel: +39-0737-632840 Mobile: +39-347-1957021 B&B Poggio Paganico Loc. Paganico 62032 Camerino Tel: +39-0737-644489 Mobile: +39-340-3188476 B&B Il Mandorlo in Fiore Via Le Mosse, 25 62032 Camerino Tel: +39-0737-633048 Mobile: +39-339-6214347 B&B Camerte Fraz. Mergnano S. Savino Via Berta, 5 62032 Camerino Tel: +39-06-7180753 Mobile: +39-328-8419245 B&B Torre Tenosa Loc. Santa Lucia, 13 62032 Camerino Tel: +39-0737-633500 Mobile: +39-334-1846842 B&B Palomba Loc. Palombare, 2 62032 Camerino Tel: +39-0737-644121 Advised Hotels/Country Houses Camerino Albergo Ristorante I DUCHI *** Via V. Favorino, 72 62032 Camerino Tel: +39-0737-630440 Fax: +39-0737-630455 http://www.hoteliduchi.it Nearby Camerino B&B COLLE RIDENTE Loc. Colle Ridente, 2 Montagnano 62032 Camerino Tel: +39-0737-637000 Mobile: +39-339-4818118 http://www.colleridente.it/camerino.htm Agriturismo FATTORIA DI CIGNANO Loc. Cignano n.5 62032 Camerino Tel: +39-0737-633595

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