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DNA: Replication

DNA: Replication. Chargaff’s Rule. %G=%C and %A=%T. duh. X-ray Diffraction. Rosalind Franklin was able to obtain a clear visible representation that the structure of the DNA was a double helix. Watson and Crick. Built a model of the double helix that conformed to Franklin’s research.

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DNA: Replication

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  1. DNA: Replication

  2. Chargaff’s Rule • %G=%C and %A=%T duh

  3. X-ray Diffraction • Rosalind Franklin was able to obtain a clear visible representation that the structure of the DNA was a double helix.

  4. Watson and Crick • Built a model of the double helix that conformed to Franklin’s research.

  5. DNA: Replication • produce DNA molecules that have 1 strand of parental DNA and 1 strand of new DNA. • This is called semi-conservative replication.

  6. DNA Template strand 5’ 3’ Replication fork 5’ 3’ DNA helicase RNA primase Unwinds and unzips Hey … nucleotides… match 5’ DNA polymerase Wks 5′ to 3′, removes primer, replaces w/ nucleotides 3’ Okasaki fragment ligase Glue .. Links P and sugar 3’ 3’ 5’ 5’ 3’ 5’ Lagging strand Leading strand

  7. DNA helicase RNA primase

  8. copied with less than one mistake in a billion nucleotides.  This is equal to a person copying 100 large (1000 page) dictionaries word for word, and symbol for symbol, with only one error for the whole process! http://www.contexo.info/DNA_Basics/DNA%20Replication.htm

  9. Other impt vocab Enzymes Helicase…. unzips Template strand…. Orig. DNA RNA primase…. “primes” strand .. finds appropriate bases .. And puts temporary fill Leading strand…. Lagging strand…. Okasaki fragment DNA Polymerase…. Wks 5’ to 3’ , places nucleotides on template strand Replication fork Ligase…. glue

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