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Supporting tissues : cartilage and bone Anna L. Kiss

Supporting tissues : cartilage and bone Anna L. Kiss Department of Anatomy , Histology and Embryology Semmelweis University Budapest 2018. Supporting tissue. Function : supports the body Structure : cells + extracellular matrix Origin : mesoderm Types : cartilage bone.

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Supporting tissues : cartilage and bone Anna L. Kiss

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  1. Supportingtissues: cartilage and bone Anna L. Kiss Department of Anatomy, Histology and Embryology Semmelweis University Budapest 2018

  2. Supportingtissue • Function: supportsthe body • Structure: cells + extracellularmatrix • Origin: mesoderm • Types: cartilage bone

  3. Cartilage CellsExtracellularmatrix chondroblasts chondrocytes osteoblasts osteocytes osteoclasts groundsubstance fibers

  4. Cells + extracellularmatrix • Cells: chondrocytes • Extracellularmatrix: fibers (collagen, elastic) + groundsubstance proteoglycans glycoproteins: chondrocalcin, cartilagematrix protein (CMP), chondronectinfibronectin

  5. Extracellularmatrix • Proteoglycanes+adhesionmolecules • filamentuosmolecules: 3 dimensionalnetwork – gelatinuosmaterial • is abletobindlargeamount of water – flexibility (turgor)

  6. GAG: • Hyaluronicacid: glucuronicacid + N-acetilglucosamin • Chondroitinsulfate: N-acetyl-galactosamin • Keratansulfate: N-acetyl-glucosamin + sulfatedgalactose Proteoglycane: „core” protein + chondroitinsulfate and keratansulfate

  7. Proteoglycan GAG chains HA-binding region Core protein hyaluronic acid link protein

  8. Types of cartilage • Hyalin: functional unit: chondron: coversthebonysurfaces of thejoints • Elastic • Fibrous: intervertebraldisc, temporomandibularjoint

  9. chondroblasts

  10. Chondron: chondrocytes basophylic capsule territorial matrix

  11. hyalin cartilage

  12. elastic cartilage

  13. fibrous cartilage

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