1 / 17

Prostate Cancer Screening

Prostate Cancer Screening. Assistant Professor Charles Chabert Men’s health Seminar Ballina April 2011. prostates.com.au. What is the Prostate?. Walnut sized gland under the bladder Shaped like a dognut Part of the male reproductive system. prostates.com.au. What is Prostate Cancer?.

marlow
Download Presentation

Prostate Cancer Screening

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Prostate Cancer Screening Assistant Professor Charles Chabert Men’s health Seminar Ballina April 2011 prostates.com.au

  2. What is the Prostate? Walnut sized gland under the bladder Shaped like a dognut Part of the male reproductive system prostates.com.au

  3. What is Prostate Cancer? • Malignant growth within the prostate • Grows independently of normal body regulatory processes • Has the ability to spread to other systems prostates.com.au

  4. How common is Prostate cancer? • Increasing incidence over the last 2 decades • Around 20 000 new diagnoses each year • Around 3000 deaths annually prostates.com.au

  5. What are the Risk Factors? • Age • Family History • Race • Diet prostates.com.au

  6. How is it detected? • Prostate cancer is aymptomatic: development of urinary symptoms is a late feature • Detected by combination of digital exam and PSA test prostates.com.au

  7. The PSA Test • PSA (Prostate Specific Antigen) is produced by the prostate • Function of prostate is to liquify semen • PSA Binds to serum proteins in the blood stream • PSA is currently the best serum marker for prostate cancer prostates.com.au

  8. An important part of screening Despite normal PSA, 25% of men with a abnormal DRE have prostate cancer Why should you perform a DRE? Digital Rectal Examination prostates.com.au Catalona WJ et al. 1994

  9. What are the Presenting Symptoms? • Localised disease is generally asymptomatic as the majority of cancers are located in the peripheral zone. • Symptoms of LUTS are usually due to BPH, enlargement of the transitional zone. • In locally advanced disease, large cancer volume may cause LUTS.

  10. An important part of screening Despite normal PSA, 25% of men with a abnormal DRE have prostate cancer Why should you perform a DRE? Digital Rectal Examination prostates.com.au Catalona WJ et al. 1994

  11. To Screen or Not To Screen prostates.com.au

  12. Evidence as it stands • ERSCP 12 year data • 31.2% relative reduction in metastatic disease • Swedish study shows 50% reduction in CAP mortality over 14 years • 293 invited to screen • 12 diagnosed to prevent 1 CAP death prostates.com.au

  13. Is this PSA normal? prostates.com.au Catalona AUA 2005 Abs 953, Oesterling JE et al 1993

  14. Risk of Prostate Cancer in Asymptomatic Men with Normal DRE? prostates.com.au Adapted from Thompson, IM et al 2004

  15. TransRectal Ultrasound (TRUS) guided biopsy performed under local anaesthetic The Diagnosis TRUS-guided biopsy of prostate prostates.com.au

  16. Take Home Points • Lifestyle modification • PSA screening reduces the risk of dying from prostate cancer & reduces the risk of metastatic disease • Urological Society recommendations: test from age 40years prostates.com.au

  17. Questions? The Prostate Clinic @Drcchabert prostates.com.au

More Related