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Natural Selection

Natural Selection. Variation. Natural Selection. Variation Heredity. Natural Selection. Variation Heredity Differential Survival. Sewell Wright (1899-1988). Fitness Landscape. 4. Multi-dimensional spaces. {x,y,z}. Generalize to:. {x,y,z,a,b,c,d,e}. Multi-dimensional spaces.

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Natural Selection

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  1. Natural Selection Variation

  2. Natural Selection Variation Heredity

  3. Natural Selection Variation Heredity Differential Survival

  4. Sewell Wright (1899-1988) Fitness Landscape 4

  5. Multi-dimensional spaces {x,y,z} Generalize to: {x,y,z,a,b,c,d,e}

  6. Multi-dimensional spaces {x,y,z} Generalize to: {x,y,z,a,b,c,d,e} Show K-means model

  7. Ronald Fisher (1890-1962) Fisher’s Fundamental Theorem R. A. Fisher's so-called fundamental theorem of natural selection: "The rate of increase in fitness of any organism at any time is equal to its genetic variance in fitness at that time."[1] Or, in more modern terminology: "The rate of increase in the mean fitness of any organism at any time ascribable to natural selection acting through changes in gene frequencies is exactly equal to its genetic variance in fitness at that time".[2] 7

  8. Information and Matter Natural history Evolvability Modularity: Evo Devo Evolution of Cooperation/Eusociality

  9. DNA

  10. DNA

  11. Transcription

  12. Translation Notion of “gene expression”

  13. Epigenetics From Wikipedia: “Epigenetics is the study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence.” http://www.pbs.org/wgbh/nova/body/epigenetics.html Is epigenetics why cloned animals don’t fare well?

  14. Genetic regulation

  15. Genetic Switches (in “non-expressed” regions) Lac Operon http://www.youtube.com/watch?v=oBwtxdI1zvk

  16. Genetic Regulatory Networks

  17. Random Boolean Networksas models of genetic regulatory networks

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