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INBRE Steering Committee Informational Meeting

INBRE Steering Committee Informational Meeting. INBRE Competitive R enewal. Submitted: July 29, 2014 Funding Period: May 1, 2015 – April 30, 2020 Study Section Review: November 2014 Council Meeting: January/February 2015. Organizational Structure of the Arkansas INBRE.

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INBRE Steering Committee Informational Meeting

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  1. INBRE Steering Committee Informational Meeting

  2. INBRE Competitive Renewal Submitted: July 29, 2014 Funding Period: May 1, 2015 – April 30, 2020 Study Section Review: November 2014 Council Meeting: January/February 2015

  3. Organizational Structure of the Arkansas INBRE

  4. INBRE Competitive Renewal Administrative Core Bioinformatics Core Research Technology Core Developmental Research Project Program

  5. Director: Larry Cornett, UAMS Admin Core Specific Aim 1. Provide overall operational support to the network (i.e., provide budgetary and fiscal services, organize and conduct Steering Committee and External Advisory Committee meetings). Specific Aim 2. Provide scientific leadership to coordinate research activities within the Arkansas INBRE’s thematic scientific focus (i.e., training, mentoring, career development). Specific Aim 3. Broaden opportunities for undergraduate participation in research in Arkansas, regardless of the location of the student’s home or educational institution.

  6. Admin Core Contd. Specific Aim 4. Foster statewide networking and communication among INBRE programs and participants. Specific Aim 5. Support programs to expand participation by members of underrepresented minority groups in the Arkansas INBRE. Specific Aim 6. Represent the Arkansas INBRE in the national and regional networks of IDeA programs.

  7. INBRE Competitive Renewal Administrative Core Bioinformatics Core Research Technology Core Developmental Research Project Program

  8. Bioinformatics Core Co-Directors Galina Glazko, UAMS Elizabeth Pierce, UALR Specific Aim 1. Provide training in bioinformatics to support biomedical research across Arkansas. Specific Aim 2. Provide bioinformatics research support and consulting services to investigators in the Arkansas INBRE network.

  9. Bioinformatics Core Contd. This fall 2014, we are welcoming 2 new MS students and 2 new PhD students So far this year we have graduated 2 PhD Students Our current student head count stands at 22 students With the new MScurriculum finalized, we can focus this year on recruiting students interested in pursuing research in the following 4 areas:  Drug Design  Integrated Bioinformatics & Genomics  Computational Biology  Biomedical Informatics

  10. Workshops in the Fall/Spring Semesters • Building and Using a Rocks Cluster for Bioinformatics • Survey of Bioinformatics Tools on a Linux System • Machine Learning for Bioinformatics • Bash Scripting for Bioinformatics • Processing Next-gen Sequence Data on a Linux System

  11. New Ways to Support Research The Arkansas INBRE webpage and a Bioinformatics Core Support Request Formare available on the Division of Biomedical Informatics website (http://dbmi.uams.edu/) The listserv INBRE Research Support with the email address of inbre_research_support@uams.eduhas been created and Support Requests are automatically sent to gvglazko@uams.edu; YRahmatallah@uams.edu; phwilliams@ualr.edu. These changes will be announced on the Arkansas INBRE Bioinformatics Core and Arkansas Bioinformatics Network webpages GSAR (“Gene Set Analysis in R”) is freely available on the Bioconductor website www.bioconductor.org and will have a link on the DBMI website and the Arkansas INBRE page

  12. Plans to Facilitate Collaboration and Training • MCBIOS 2015 will be held at the Statehouse Convention Center , Little Rock, March 12 - 14, 2015 • UALR/UAMS Graduate Program in Bioinformatics will have a recruiting booth • A One-Day Omics Workshopwill be organized with 3 options in conjunction with the MCBIOS Conference: • TranscriptomicsData Analysis Workshop presented by Dr. Frank Emmert-Streib, Center for Cancer Research and Cell Biology , Queen's University Belfast , UK • Genomics Data Analysis Workshop, TBN • Proteomics (Metabolomics?) Data Analysis Workshop, TBN • We will hold an Omics Poster Session as part of the UAMS Research Day (also coordinated with the UALR Research Day) in April 2015

  13. INBRE Competitive Renewal Administrative Core Bioinformatics Core Research Technology Core Developmental Research Project Program

  14. Director: Alan Tackett, UAMS Research Technology Core Diagram of the Arkansas INBRE Research Technology Core. The three branches of this core will facilitate cutting-edge research and provide education on state-of-the-art technologies at Arkansas INBRE partner and affiliated institutions.

  15. Specific Aim 1. Support undergraduate research by providing Core Facility Vouchers to undergraduate faculty and students. • Faculty Research Core Facility Vouchers  • Student Research Core Facility Vouchers • Faculty Curriculum Core Facility Vouchers Specific Aim 2. Invest in cutting-edge core facility technology development by providing Core Facility Development Awards to core facilities at UAMS and UAF. • Core facilities will apply for funds to implement some new approach/service into their facility • Awards will be up to $3,500, and we anticipate awarding 4–6 yearly • Priority will be given to core facilities that have large numbers of INBRE-supported PUI users • These awards will provide a mechanism by which the Arkansas INBRE can support Core Facility development, while still providing general access to all Core Facilities for PUI users

  16. Specific Aim 3. Promote the Arkansas INBRE Research Technology Core and provide on-site educational seminars at Arkansas undergraduate institutions. • On-site promotional activities and educational seminars • a one-hour seminar (30 minutes for Dr. Tackett to describe opportunities through the Research Technology Core and 30 minutes of training given by a core facility director) • display of a Research Technology Core poster detailing the Core Facility Voucher Program and available core facilities • one-on-one meetings with INBRE-funded faculty and students • meetings with non-INBRE-funded faculty and students. • Social Media Hub

  17. Diagram of the Arkansas INBRE Research Technology Core personnel and roles.

  18. INBRE Competitive Renewal Administrative Core Bioinformatics Core Research Technology Core Developmental Research Project Program

  19. Developmental Research Project Program (DRPP) Director: Helen Beneš, UAMS Specific Aim 1. Recruit new faculty to select partner institutions. Specific Aim 2. Support biomedical research by funding research grants for mentored faculty at partner and affiliate institutions. Specific Aim 3. Sustain the research career development of faculty at partner and affiliate institutions by mentoring and other activities.

  20. DRPPContd.

  21. Funding Mechanisms — Types of Grants

  22. Career Development Research Career Development Groups – “Chalk talks” to help Project Leaders with research development Seminar Series – up to $1,200 for Project Leaders to invite speakers to their home institution Mini-Sabbaticals for Technical Training– up to $7,000 for Project Leaders to learn special techniques at core facilities Proposal-Writing Workshops– Arkansas INBRE Project Leaders will be able to take advantage of the annual AREA grant writing workshops offered by Kentucky INBRE

  23. Proposed Timeline

  24. Proposal Review Committee Gwen V. Childs, PhD, Professor & Chair, Neurobiology & Developmental Science, UAMS Andrea Duina, PhD, Assoc. Professor, Biology, Hendrix College Howard Hendrickson, PhD, Assoc. Professor, Pharmaceutical Sciences, UAMS Argelia Lorence, PhD, Professor, Chemistry and Physics, ASU David Paul, PhD, Assoc. Professor, Chemistry and Biochemistry, UAF Marty Perry, PhD, Assoc. Professor, Chemistry, OBU Antonie Rice, PhD, Professor & Chair, Dept. of Chemistry and Physics Jerry Ware, PhD, Professor, Physiology and Biophysics, UAMS

  25. Research Development Committee Jerry Darsey, PhD, Assoc. Professor, Chemistry, UALR INBRE mentor; previous INBRE proposal reviewer; chemistry/biochemistry Robert J. Griffin, PhD, Assoc. Professor, Radiation Oncology, UAMS INBRE mentor for current Project Leader; molecular biology/cell and cancer biology Lori Hensley, PhD, Assoc. Professor, Biological Sciences, OBU INBRE Project Leader (current), cell and cancer biology Brent Hill, PhD, Assoc. Professor, Biology, UCA INBRE Project Leader (current), physiology/cell biology Malathi Srivatsan, PhD, Assoc. Professor, Biological Sciences, ASU INBRE Project Leader (former), neuroscience/cell biology/molecular biology Daniel Voth, PhD, Assist. Professor, Microbiology and Immunology, UAMS INBRE mentor for current Project Leader; infectious disease/molecular biology/cell biology

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