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Microarray Experiments Part I: Pre-processing and Normalization

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Microarray Experiments Part I: Pre-processing and Normalization

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    7. Basic Biology of Oxidative Stress

    35. Some researchers suggested to use other MM sequences in order to alleviate this tracking. MM could be created by changing more than one base in PM sequence and by placing MM bases in different positions in the MM sequence (Nimblegen chips). Other researchers (Irizarry, Speed, et al.) suggested only using PM (Robust Multiarray Average). This approach would allow space used for MM to be used for other PM, thus allowing for twice as many sequences of interest to be printed onto an array.

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