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Med Tox Board Review: Buzzwords for the Boards

Med Tox Board Review: Buzzwords for the Boards. GP Daubert 2014. “Egg-shell” calcifications of hilar lymph nodes, increase risk of tuberculosis, upper lung disease. Silicosis.

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Med Tox Board Review: Buzzwords for the Boards

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  1. Med Tox Board Review:Buzzwords for the Boards GP Daubert 2014

  2. “Egg-shell” calcifications of hilar lymph nodes, increase risk of tuberculosis, upper lung disease

  3. Silicosis

  4. Pneumoconiosis with hilar adenopathy; clinically and pathologically identical to sarcoidosis except no eye involvement; lymphocyte transformation test

  5. Berylliosis

  6. Porphyria, pemba yara, spongiform encephalopathy, outbrake in Turkey in 1956

  7. Hexachlorobenzene

  8. Isolated thrombocytopenia, “bathtub refinisher’s lung”, sensitizing agent - largest recognized cause of occupational asthma

  9. Toluene di-isocyanate (TDI)

  10. Hepatic angiosarcoma

  11. Vinyl chloride

  12. Pesticide operator with sterility, altered sex ratio in offspring

  13. Dibromochloropropane • (DBCP) • Re: “Da Balls Can’t Produce”

  14. Phossy jaw

  15. Yellow phosphorus

  16. Brown lung, “Monday morning tightness”, byssanosis

  17. Cotton

  18. Hypertension, Saturnine gout, renal failure, microcytic anemia

  19. Adult lead poisoning

  20. “Silver solderers”, proximal RTA, itai-itai disease in Jintsu River basin, acute lung injury, renal failure

  21. Cadmium

  22. Perforated nasal septum, lung cancer, painless ulcers, “blackjack disease”, Type IV hypersensitivity dermatitis

  23. Chromium

  24. Hairdresser with hearing loss, renal failure, methemoglobinemia

  25. Bromate

  26. The cholera toxin activates cAMP, which intern stimulate CFTR causing a dramatic efflux of ions and water from infected enterocytes. • What popular ‘pop’ band was associated with this disease?

  27. The Go-Gos

  28. Acute psychosis with elevated serum chloride level

  29. Bromide

  30. Solvent, epoxide metabolite (hepatotoxicity), “Degreaser’s flush”, trigeminal neuralgia

  31. Trichloroethylene

  32. Viscous rayon, increase rate of atherosclerosis; disulfiram and metam sodium metabolites; basal ganglia toxin; associated with spontaneous abortions; decreased spermatogenesis, craniofacial abnormalities; optic nerve and retinal degeneration

  33. Carbon disulfide

  34. The percentage of sick people who are identified as having the condition • or • The likelihood of a test being positive if the condition is present

  35. Sensitivity

  36. A result of 100% means that the test recognizes all healthy people as healthy • or • The likelihood of the unaffected individuals correctly having a negative test

  37. Specificity

  38. Condition + - True Positive False Positive(Type I error) + → PPV Testoutcome False Negative(Type II error) True Negative - → NPV ↓Sensitivity ↓Specificity

  39. Condition Yes No → Absolute Risk Exposed (ARE) A/(A+B) B A Yes Risk Factor → Absolute Risk Unexposed (ARU) C/(C+D) C D No Attributable Risk (Risk Difference) = ARE – ARU Relative Risk = ARE/ARU Odds Ratio = (A/C)/(B/D)

  40. Solvent, acute CNS depression, arrhythmias, AML, Hodgkin’s lymphoma, paroxysmal nocturnal hemoglobinuria

  41. Benzene

  42. Wastewater treatment worker with sensory and motor distal axonal neuropathy (axonopathy)

  43. What singer is associated with Hymonoptera-induced anaphylaxis?

  44. Sting

  45. Wastewater treatment worker with sensory and motor distal axonal neuropathy (axonopathy), also has blue discoloration of hands and feet, desquamation, and pulmonary irritation

  46. Acrylamide

  47. Ginger Jake, NTE inhibitor, sensory-motor neuropathy, 1960 Morocco disaster

  48. Triorthocresyl phosphate (TOCP)

  49. Minamata Bay

  50. Methylmercury

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