170 likes | 209 Views
Integration of Metabolism Chapter 27. Regulatory Themes. Allosteric interactions Covalent modification Adjustment of enzyme levels Compartmentalization Metabolic Specialization of Organs. Control sites. Glycolysis. Control sites. Citric Acid Cycle/Oxidative Phosphorylation
E N D
Regulatory Themes • Allosteric interactions • Covalent modification • Adjustment of enzyme levels • Compartmentalization • Metabolic Specialization of Organs
Control sites • Glycolysis
Control sites • Citric Acid Cycle/Oxidative Phosphorylation • ATP and respiratory control • Pyruvate Dehydrogenase
Control sites • Gluconeogenesis and Pentose Phosphate pathway • PPP and NADPH for reductive biochemistry • F-1,6-Bis phosphatase
Control sites • Glycogen Synthesis/Breakdown • Reciprocal hormone regulation
Control sites • Fatty Acid Synthesis • Citrate • Malonyl CoA and carnitine
Relations between organs Sugars and proteins