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Adolescent cancer- an introduction.

Adolescent cancer- an introduction. Mary Taj Royal Marsden Hopsital. The period between childhood and adulthood. Age cut of variable from 13 years –25 years Treated variably in adult or paediatric centres 200 cases/million/year in 15 – 20 year

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Adolescent cancer- an introduction.

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  1. Adolescent cancer- an introduction. Mary Taj Royal Marsden Hopsital

  2. The period between childhood and adulthood • Age cut of variable from 13 years –25 years • Treated variably in adult or paediatric centres • 200 cases/million/year in 15 – 20 year • How does cancer in adolescents differ from childhood and adult cancers? • Which protocols are these patients best treated on.

  3. Pattern of incidence of adolescent cancer from the Northern malignant disease registries

  4. Hodgkins disease NHL Germ cell Leukaemia CNS Soft tissue sarcoma Bone tumours Melanoma Thyroid Others 16% 8% 16% 11% 10% 7% 5% 7% 7% 12% Malignancies 15-19 yrs US SEER data 60-75% tumours Paediatric tumours

  5. AML RMS ALL EWINGS OSTEOSARCOMA OTHER SARCOMAS NHL RENAL TUMOURS 5 year survival % Gap in survival in 15-19 yr v 0-14 yr olds

  6. Treating adolescents on paediatric protocols

  7. Where to treat adolescents…. • Multidisciplinary team approach • Psychosocial support for dealing with issues of compliance, independence, jobs, relationships etc • Need entry in trials

  8. Summarise • Adolescents with cancer often fall between adult and paediatric oncology centres. • Survival worse than in children • Further trials needed but some evidence EFS better on paediatric protocols • Need to be treated in units where the psychosocial needs of this vulnerable group can be met. • Better cooperation between paediatric & medical oncologists required.

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