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OSTEOMYELITIS

OSTEOMYELITIS. an acute or chronic inflammatory process in the medullary spaces or cortica l surfaces of bone ……………….. the initial site of involvement most often from a………….. periapical abscess. The second most common cause….. Physical injury. Most cases are……………………… infectious.

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OSTEOMYELITIS

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  1. OSTEOMYELITIS

  2. an acute or chronicinflammatory process in the medullaryspaces or cortical surfaces of bone ……………….. the initial site of involvement most often from a………….. periapical abscess. The second most common cause….. Physical injury Most cases are……………………… infectious

  3. all ages. a strong male predominance. Most cases involve the mandible 1.More diffuse blood supply 2.The grater proportion of cancellous bone ……….In maxilla .1Acute osteomyelitis when an acute inflammatory process spreads through the medullary spaces of the bone 2.Chronic osteomyelitis the defensive response leads to the production of granulation tissue……. an attempt to wall off the infected area.

  4. Acute osteomyelitis. signs and symptomsof an acute inflammatory process that has typically been less than1 month in duration. Fever leukocytosis Lymphadenopathy significant sensitivity soft-tissue swelling Usually,no radiographic evidence Unless approximately 60 %Demineralization of the bone an ill-defined radiolucency

  5. On occasion………… paresthesia of the lower lip drainage exfoliation of fragments of necrotic bone (sequestrum). central radiopaque mass of necrotic bone. Involucrum the mass of encased nonvital bone that may become surrounded by vital bone,

  6. Chronic osteomyelits If acute osteomyelitis is not resolved or primarily without a previous acute episode. Swelling Pain sinus formation purulent discharge, sequestrum formation tooth loss pathologic fracture. a patchy, ragged, and ill-defined radiolucency often contains …….. central radiopaque sequestra.

  7. Histopathologic Features acute osteomyelitis Generation of biopsy is not common ….. predominantly liquid content and lack of a soft-tissue component. When submitted, the material consists …………….necrotic bone. a loss of the osteocytes from their lacunae Normal woven bone

  8. bacterial colonization Necrotic debries

  9. acute inflammatory infiltrate consisting of PMNs.

  10. Chronic osteomyelitis a significant soft-tissue component that consists of chronically or subacutely inflamed fibrous connective tissue filling the intertrabecular areas of the bone.

  11. irregular fragment of devitalized bone surrounded by dense fibrous tissue heavily infiltrated by plasma cells, lymphocytes, and only a few granulocytes

  12. Treatment and Prognosis Acute osteomyelitis…… 1.antibiotics 2. drainage. Chronic osteomyelitis. 1.similar antibiotics ……..but intravenouslyin high doses. 2.Surgical removal of all infected materialsurgical down………….. to good bleeding bone .

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