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Actimask® Ibuprofen 92S

Actimask® Ibuprofen 92S. Attractive Markets for IBU & APAP. Global OTC internal analgesic market >$11 BILLION More than half is APAP & Ibuprofen. United States. Association of the European Self-Medication Industry. Actimask Ibuprofen 92S.

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Actimask® Ibuprofen 92S

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  1. Actimask® Ibuprofen 92S

  2. Attractive Markets for IBU & APAP Global OTC internal analgesic market >$11 BILLION More than half is APAP & Ibuprofen United States Association of the European Self-Medication Industry

  3. Actimask Ibuprofen 92S • Proprietary hydrogel coated ibuprofen for orodispersible dose forms: • Product line extensions and additions

  4. Actimask Ibuprofen 92SFeatures & Benefits

  5. Actimask Ibuprofen 92STaste- Masking Performance TASTE-MASKING ZONE

  6. Actimask Ibuprofen 92S Exceeds Compendial Dissolution

  7. Actimask Ibuprofen 92S Product Information

  8. Actimask Ibuprofen 92SPilot PK Randomized, open label, single dose, crossover design in 13 adults 100mg ODT and ODP with Actimask Ibuprofen 92S vs. 100mg Junior Advil® Chewable ODP  ODT REFERENCE Advil® is a registered trademark of Wyeth LLC

  9. Actimask Ibuprofen 92SPilot BiostudyConslusions • Actimask taste-masking provides excellent organoleptics without altering ibuprofen PK • Tablet formulations can be expected to be bioequivalent to each other in a formal biostudy with more patients (24-36 patients) • The 100mg results are relevant for higher doses (200 and 400mg) because ibuprofen pharmacokinetics are linear • twice the dose should have twice the AUC and Cmax

  10. Actimask Ibuprofen 92SParticle Size Distribution & Physical Characteristics

  11. Actimask Ibuprofen 92SProduct Specifications

  12. Thank you, merci, danke, спасибо, arigato, gracias, obrigado, grazie, diolchynfawr, शुक्रिया, شُكْرًا, 谢谢

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