1 / 72

Surgical Treatment of Laryngomalacia

Overview. LaryngomalaciaPatient presentation and work-upMedical managementSurgical intervention. Differential Diagnosis of Noisy Breathing. Stridor. A harsh, high pitched musical sound that results from turbulent airflow through the upper airwayEtiology may range from mild illness to severe, life-threatening situation.

rory
Download Presentation

Surgical Treatment of Laryngomalacia

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


    1. Surgical Treatment of Laryngomalacia Dept of Otolaryngology Garrett Hauptman MD Matthew Ryan MD June 15, 2005

    2. Overview Laryngomalacia Patient presentation and work-up Medical management Surgical intervention

    3. Differential Diagnosis of Noisy Breathing

    4. Stridor A harsh, high pitched musical sound that results from turbulent airflow through the upper airway Etiology may range from mild illness to severe, life-threatening situation

    5. Stridor Etiology Congenital Inflammation Trauma Foreign bodies

    6. Stridor Presentation Variable age of onset Patient typically presents with sudden onset of symptoms Acquired stridor (inflammation, trauma, foreign bodies) is more likely than congenital stridor to require airway intervention

    7. Congenital Stridor Eighty-five percent of children under 2.5 years presenting with stridor have a congenital etiology Often not present at birth Typically presents prior to four months of age

    8. Assessing Stridor Determination of respiratory phase in which sound is noted Inspiratory Biphasic Expiratory

    9. Inspiratory Stridor Result of supraglottic obstruction High-pitched

    10. Biphasic Stridor Result of extrathoracic tracheal obstruction including Glottis Subglottis Intermediate pitch

    11. Expiratory Stridor Result of intrathoracic tracheal obstruction Associated with retraction of Sternum Costal cartilage Suprasternal tissue

    12. Laryngomalacia a condition in which the tissues of the entrance of the larynx collapse into the airway when the patient inspires Secondary to continued immaturity of larynx Cause remains enigmatic

    13. Laryngomalacia Most common cause of stridor in infancy Most common congenital laryngeal anomaly 2 males: 1 females

    14. Contributing Factors of Laryngomalacia Anatomic Shortening of aryepiglottic folds and anterior collapse of cuneiform and corniculate cartilage Prospective case-control by Manning et al in 4/05 created a ratio of aryepiglottic fold length to glottic length Severe laryngomalacia = 0.380 Control = 0.535 Floppy or tubular epiglottis

    15. Contributing Factors of Laryngomalacia Neurologic Immature neuromuscular control and movement Inflammatory Reflux can induce posterior supraglottic edema and secondarily laryngomalacia

    16. Symptoms of Laryngomalacia Onset typically days to weeks after birth Most commonly within the first 2 weeks of life Inspiratory stridor Low pitch with a fluttering quality secondary to circumferential rimming of the supraglottic airway and aryepiglottic folds More prominent when child is Supine Agitated Louder quality with more forceable inspiration Often associated with general noisy respiration

    17. Diagnosis of Laryngomalacia Clinical assessment Suspect laryngomalacia in a neonate with auscultation of inspiratory stridor Confirm suspicion with flexible laryngoscopy

    18. Flexible Laryngoscopy Best performed with Unanesthetized child Upright position 1.9mm laryngoscope Scope should be passed through both nasal passages Evaluate vocal cord mobility

    19. Flexible Laryngoscopy Findings with Laryngomalacia Cyclical collapse of supraglottic larynx with inspiration Short aryepiglottic folds Draw the cuneiform and corniculate cartilages forward over the laryngeal inlet resulting in prolapse during inspiration

    20. Laryngomalacia Seen by Flexible Laryngoscopy

    21. Laryngomalacia Seen by Flexible Laryngoscopy

    22. Laryngomalacia Seen by Flexible Laryngoscopy

    23. Laryngomalacia Seen by Flexible Laryngoscopy

    24. Laryngomalacia Classification Type I: inward collapse of the aryepiglottic folds

    25. Laryngomalacia Classification Type II: long tubular epiglottis which curls on itself Often occurs with type I laryngomalacia

    26. Laryngomalacia Classification Type III: anterior, medial collapse of corniculate and cuneiform cartilages

    27. Laryngomalacia Classification Type IV: posterior inspiratory displacement of the epiglottis against the posterior pharyngeal wall or inferior collapse to the vocal folds

    28. Laryngomalacia Classification Type V: short aryepiglottic folds

    29. Radiographic Evaluation Unnecessary Inspiratory plain film with neck extension May show medial and inferiorly displaced arytenoids and epiglottis Fluoroscopy May demonstrate collapse of supraglottic structures with inspiration

    30. Medical Management of Laryngomalacia Reassuring parents of favorable prognosis Condition is usually self-limiting Position adjustments More prominent when supine or agitated Consider reflux precautions Frequent evaluation by pediatrician to assess: Growth Feeding Breathing

    31. Surgical Management of Laryngomalacia Rarely necessary as condition is self-limiting Severe symptoms are surgical indications Life-threatening airway obstruction Inability to feed orally Cor pulmonale Failure to thrive

    32. Surgical Management of Laryngomalacia Prior to 1980s, tracheotomy was treatment Tracheotomy bypassed area of obstruction until supraglottic pathology spontaneously resolves Today, this strategy only employed in severely affected infant

    33. Surgical Management of Laryngomalacia Supraglottoplasty Addresses area of obstruction directly May be performed with several instruments Microlaryngeal instruments Carbon dioxide laser Microdebrider Unilateral should be considered initially

    34. Surgical Management of Laryngomalacia Direct laryngoscopy and bronchoscopy should be considered prior to surgery In 1996, Mancuso et al performed a retrospective study to determine necessity of rigid endoscopy in management of laryngomalacia and associated synchronous airway lesions Synchronous airway lesions (SALs) 18.9% Clinically significant SALs 4.7% SALs requiring intervention 3.9%

    35. Tissue Targeted by Supraglottoplasty

    36. Surgical Management of Laryngomalacia Post-operative management Usually left intubated overnight Antibiotics should be given at least 5 days post-operatively Antireflux precautions Medication Positioning

    37. Overview of Literature Review History of supraglottoplasty Severe laryngomalacia and expected treatment outcomes Unilateral versus bilateral Surgical techniques Failures and complications

    38. History of Supraglottoplasty

    39. History of Supraglottoplasty 1922: Dr. Iglauer described endoscopic removal of supraglottic tissue with nasal snare 1984: Dr. Lane described removal of corniculate cartilage and redundant arytenoid mucosa 1985: Dr. Seid described CO2 laser for treatment of laryngomalacia in 3 patients

    40. Severe Laryngomalacia and Expected Treatment Outcomes

    41. Severe Laryngomalacia Defined In 1995, Roger et al published a retrospective study of 115 patients s/p resection of aryepiglottic folds with or without CO2 laser Success rate of 98% with 30 month follow-up Two children required tracheotomies (failed supraglottoplasty) Seven patients required revision surgery

    42. Severe Laryngomalacia Defined Established criteria defining severe laryngomalacia- presence of 3 is indication for endoscopic surgery dyspnea at rest and/or severe dyspnea during effort feeding difficulties height and weight growth rate stagnation sleep apnea or obstructive hypoventilation uncontrollable gastroesophageal reflux history of intubation for obstructive dyspnea effort hypoxia (10% higher than the normal values for the same age group) effort hypercapnia (10% higher than the normal values for the same age group) abnormal polysomnography with an increased apnea/obstructive hypoventilation index

    43. Resolution and Intervention for Laryngomalacia In 1999, Olney et al performed a retrospective chart review to determine Outcome of infants who do not undergo routine direct laryngoscopy and bronchoscopy Age at which laryngomalacia resolves Outcome of supraglottoplasty as a function of the type of laryngomalacia and the presence of concomitant disease

    44. Alternate Classification of Laryngomalacia

    45. Resolution and Intervention for Laryngomalacia Olney Results direct laryngoscopy and bronchoscopy as part of the routine evaluation of laryngomalacia is not warranted and should only be performed when there is clinical and physical evidence of a concomitant airway lesion median time to resolution of isolated laryngomalacia was 36 weeks, and by 72 weeks, 75% of infants were free of stridor

    46. Resolution and Intervention for Laryngomalacia Olney results (cont.) Supraglottoplasty was determined to be necessary in approximately 15-20% of affected infants Apneic episodes Failure to thrive

    47. Unilateral Versus Bilateral

    48. Unilateral Supraglottoplasty In 1995, Kelly et al evaluated effectiveness of unilateral supraglottoplasty Retrospective review of 18 patients with severe laryngomalacia treated with unilateral CO2 laser supraglottoplasty 3 patients required contralateral supraglottoplasty Obstructive symptoms relieved in 94% Patient without obstructive relief had tracheomalacia secondary to prior tracheotomy

    49. Unilateral Versus Bilateral Supraglottoplasty In 2001, Reddy et al evaluated the efficacy of unilateral versus bilateral supraglottoplasty Retrospective review of 106 patients 59 patients with bilateral supraglottoplasty 47 patients with unilateral supraglottoplasty

    50. Unilateral Versus Bilateral Supraglottoplasty Reddy Results 96% with resolution of clinically significant laryngomalacia 15% of unilateral supraglottoplasty patients required contralateral supraglottoplasty 3% of bilateral supraglottoplasty developed supraglottic stenosis No patients undergoing unilateral supraglottoplasty developed supraglottic stenosis

    51. Surgical Technique

    52. Epiglottoplasty In 1987, Zalzal et al described epiglottoplasty as a new procedure 10 patients Using a laryngoscope, excised redundant mucosa from: Lateral edges of epiglottis Aryepiglottic folds Arytenoids

    53. Epiglottoplasty All patients had complete relief One patient had to undergo repeat excision Indications for operating Severe stridor with: Failure to thrive Cor pulmonale Feeding difficulties Apnea Inability to view vocal cords due to laryngeal inlet collapse

    54. CO2 Laser Supraglottoplasty In 2001, Senders et al evaluated use of CO2 laser in supraglottoplasty and role of associated anomalies on outcome Retrospective chart review of 23 patients Results Patients without associated anomalies 78% with immediate resolved symptoms 100% with symptom resolution in a week Unfavorable immediate results and long-term surgical failure all had associated anomalies Arnold-Chiari Cerebral Palsy CHARGE Association Rieger syndrome

    55. Endoscopic Aryepiglottoplasty In 2001, Toynton et al evaluated the affect of endoscopic aryepiglottoplasty on severe laryngomalacia Retrospective review of 100 patients Surgical criteria Oxygen saturation below 92% Failure to thrive

    56. Endoscopic Aryepiglottoplasty Toynton Results 94% of patients had improvement of stridor within one month 55% of these patients were completely without stridor Patients with slower progression of improvement were found to have serious neurological condition 72% of patients with preoperative feeding difficulties improved their feeding

    57. Aryepiglottic Fold Division In 2001, Loke et al examined effect of simple division of aryepiglottic fold Retrospective review of 32 cases Results 69% showed complete resolution of symptoms 22% showed partial resolution of symptoms without further surgical intervention required 6% required additional procedure 1 patient required tracheotomy

    58. Epiglottopexy In 2002, Werner et al addressed isolated posterior displacement of epiglottis 6 patients underwent epiglottopexy 4 solely epiglottopexy 2 with epiglottopexy and transection of aryepiglottic folds All patients with significant airway improvement and no effect on deglutition

    59. Epiglottopexy Treatment Algorithm

    60. Epiglottopexy

    61. Microdebrider Supraglottoplasty In 2005, Zalzal et al presented new technique to supraglottoplasty by making use of the microdebrider Case series of five patients Technique Dividing the aryepiglottic fold with microlaryngeal scissors Aryepiglottic folds are resected with microdebrider anteriorly to the lateral edge of the epiglottis posteriorly to the arytenoids cartilage Redundant supraarytenoid mucosa removed with microdebrider All patients with post-op resolution of stridor and no complications

    62. Pre-operative Laryngomalacia

    63. Division of Aryepiglottic Fold

    64. Post-operative Laryngomalacia

    65. Pre and Post-operative Laryngomalacia

    66. Complications and Failures

    67. Failures and Complications In 2003, failures and complications in supraglottoplasty were analyzed by Denoyelle et al Retrospective review of 136 patients 102 with isolated laryngomalacia 34 with additional congenital anomalies Pierre Robin Psychomotor retardation CHARGE Association Down syndrome

    68. Failures and Complications Outcome measures Persistence of dyspnea Sleep apnea Failure to thrive Need for additional treatment Presence of granuloma, edema, or web Supraglottic stenosis

    69. Supraglottic Stenosis

    70. Failures and Complications Results Failure or only partial improvement of symptoms was only seen in patients with additional congenital anomalies (8.8%) need for revision surgery was 4.4% minor complications (granuloma, edema or web) occurred in 3.7% supraglottic stenosis occurred in 4.4%

    71. Recommendations

    72. Recommendations Conservative management with close follow-up Use technique that surgeon feels most comfortable with for surgical intervention Reasonable to treat unilaterally

    73. Bibliography Bailey BJ. Head and Neck Surgery Otolaryngology 3rd Edition. 2001: 902-3. Cotton RT. Practical Pediatric Otolaryngology. 1999: 497-501. Denoyelle F, Mondain M, Gresillon N, Roger G, Chaudre F, Garabedian EN. Failures and complications of supraglottoplasty in children. Archives of Otolaryngology Head and Neck Surgery. 2003 Oct;129 (10): 1077-80. Hadfield PJ, Albert DM, Bailey CM, Lindley K, Pierro A. The effect of aryepiglottoplasty for laryngomalacia on gastro-oesophageal reflux. International Journal of Pediatric Otorhinolaryngology. 2003 Jan; 67 (1): 11-4. Iglauer S. Epiglottidectomy for the relief of congenital laryngeal stridor, with report of a case. Laryngoscope. 1922; 32: 56-59. Lane RW, Weider DJ, Steinem C, Marin-Padella M. Laryngomalacia: a review and case report of surgical treatment with resolution of pectus excavatum. Archives of Otolaryngology Head and Neck Surgery. 1984; 110: 546-51. Loke D, Ghosh S, Panarese A, Bull PD. Endoscopic division of the ary-epiglottic folds in severe laryngomalacia. International Journal of Pediatric Otorhinolaryngology. 2001 Jul 30; 60 (1): 59-63. Mancuso RF, Choi SS, Zalzal GH, Grundfast KM. Laryngomalacia: The search for the second lesion. Archives of Otolaryngology Head and Neck Surgery. 1996 Mar; 122 (3): 302-6. Manning SC, Inglis AF, Mouzakes J, Carron J, Perkins JA. Laryngeal anatomic differences in pediatric patients with severe laryngomalacia. Archives of Otolaryngology Head and Neck Surgery. 2005 Apr; 131 (4): 340-3. Olney DR, Greinwald JH Jr, Smith RJ, Bauman NM. Laryngomalacia and its treatment. Laryngoscope. 1999 Nov; 109 (11): 1770-5. Reddy DK, Matt BH. Unilateral vs. bilateral supraglottoplasty for severe laryngomalacia in children. Archives of Otolaryngology Head and Neck Surgery. 2001 Jun; 127 (6): 694-9. Roger G, Denoyelle F, Triglia JM, Garabedian EN. Severe laryngomalacia: surgical indications and results in 115 patients. Laryngoscope. 1995 Oct;105: 1111-7. Seid AB, Park SM, Kearns MJ, Gugeheim S. Laser division of the aryepiglottic folds for severe laryngomalacia. International Journal of Pediatric Otorhinolaryngology. 1985; 10: 153-8. Senders CW, Navarrete EG. Laser supraglottoplasty for laryngomalacia: are specific anatomical defects more influential than associated anomalies on outcome? International Journal of Pediatric Otorhinolaryngology. 2001 Mar; 57 (3): 235-44. Toynton SC, Saunders MW, Bailey CM. Aryepiglottoplasty for laryngomalacia: 100 consecutive cases. Journal of Laryngology and Otology. 2001 Jan; 115 (1): 35-8. Venkatakarthikeyan C, Thakar A, Lodha R. Endoscopic correction of severe laryngomalacia. Indian Journal of Pediatrics. 2005 Feb; 72 (2): 165-8. Werner JA, Lippert BM, Dunne AA, Ankermann T, Folz BJ, Seyberth H. Epiglottopexy for the treatment of severe laryngomalacia. European Archive of Otorhinolaryngology. 2002 Oct; 259: 459-64. Zalzal GH, Anon JB, Cotton RT. Epiglottoplasty for the treatment of laryngomalacia. Annals of Otology, Rhinology, and Laryngology. 1987; 96: 72-6. Zalzal GH, Collins WO. Microdebrider-assisted supraglottoplasty. International Journal of Pediatric Otorhinolaryngology. 2005 Mar; 69 (3): 305-9.

More Related