1 / 10

Orthopoxvirus/ Smallpox

Orthopoxvirus/ Smallpox. Taxonomy Target Tissues Ecology Symptoms Treatments and Prevention Research. Variola Major Most Common Most Fatal Four Types: 1)Ordinary 2)Modified 3)Flat 4)Hemorrhagic. Variola Minor Less Common Less Fatal. Taxonomy. Target Tissues. Face Arms

royi
Download Presentation

Orthopoxvirus/ Smallpox

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Orthopoxvirus/ Smallpox Taxonomy Target Tissues Ecology Symptoms Treatments and Prevention Research

  2. Variola Major Most Common Most Fatal Four Types: 1)Ordinary 2)Modified 3)Flat 4)Hemorrhagic Variola Minor Less Common Less Fatal Taxonomy

  3. Target Tissues • Face • Arms • Legs

  4. Ecology • Smallpox has been eradicated from nature • Only exists in laboratories for the purpose of creating vaccines and preventing bioterrorism.

  5. Early Symptoms • Fever • Depression • Head and Body Aches • Vomiting

  6. LaterSymptoms • Rash 3) Pustules • Fever 4) Scabs

  7. Treatments and Prevention - Vaccination, but it doesn’t work for everyone.

  8. Research Current research has been done to distinguish between Old World and Current types of the Orthopoxviruses by PCR and Electrophoresis of the crmB gene.

  9. Smallpox virus can be detected by PCR amplification of the hemagglutinin gene and then determining the melting point of the gene’s DNA will result in the identification of the virus. Research

  10. References • Prescott, Lansing M., John P. Harley, Donald A. Klein, Microbiology, New York, McGraw-Hill 2002 • Vladimir N. Loparev, Robert F. Massung, Joseph J. Esposito, Hermann Meyer; “Detection and Differentiation of Old World Orthopoxviruses: Restriction Fragment Length Polymorphism of the crmB Gene Region” JCM Vol. 39, 2001, 94-100 • Mark J. Espy, Franklin R. Cockerill III, Richard F. Meyer, Michael D. Bowen, Gregory A. Poland, Ted L. Hadfield, Thomas F. Smith, “Detection of Smallpox Virus DNA by Lightcycler PCR” JCM Vol. 40, 2002, 1985-1988 • Centers for Disease Control and Prevention, 12/12/02 US Department of Health and Human Services, 12/7/02/12/10/02 www.cdc.gov

More Related