'Constant region' presentation slideshows

T Cell Receptor & T Cell Development

T Cell Receptor & T Cell Development. Questions for the next 2 lectures : How do you generate a diverse T cell population with functional TCR rearrangements? How do you generate a T cell population that is self-MHC restricted? How do you ensure that those diverse T cell

1.56k views • 70 slides

Antibody Structure and Function

Antibody Structure and Function. W. Robert Fleischmann, Ph.D. Department of Urologic Surgery University of Minnesota Medical School rfleisch@umn.edu (612) 626-5034. Objectives. Understand the basic structure and function of antibodies Understand how antigens and antibodies interact

2.2k views • 55 slides

488 views • 33 slides

Antibodies

Antibodies. Contents. ? Structure ? Diversity ? Function ? Characteristic and Function of various classes of antibodies ? Artificial antibodies. Basic concepts ----S timulation of B cells with antigen s leads to differentiation of the B cell s to plasma cells.

520 views • 26 slides

? Structure ? Diversity ? Function

Antibodies. ? Structure ? Diversity ? Function ? Characteristic and Function of various classes of antibodies ? Artificial antibodies. Basic concepts ----S timulation of B cells with antigen s leads to differentiation of the B cell s to plasma cells.

378 views • 25 slides

Activated B -cell

a. a. Ag. Ag. Ag. B-CELL DIFFERENTIATION IN THE PERIPHERY. Memory B -cell. Activated B -cell. SOMATIC HYPERMUTATION. M ature na i ve B-cell. ISOTYPE SWITCH. Self recognition Clonal deletion. Self structure. PERIPHERAL LYMPHOID ORGANS. Available B-cell repertoire.

443 views • 25 slides

Organization and Expression of Immunoglobulin Genes

Organization and Expression of Immunoglobulin Genes. Reading. Chapter 5 Kuby et al Immunology 6 th Edition. OBJECTIVES. Define the following terms: allelic exclusion, isotype switching, affinity maturation , antibody repertoire, alternative RNA splicing, recombination signal sequence

682 views • 22 slides

Antigen and Antibody

1.59k views • 21 slides

Generation of antibody d i v e r s i t y

Generation of antibody d i v e r s i t y. Genetic Model Compatible with Ig Structure. The vast diversity of antibody specificities The presence in Ig heavy and light chains of a variable region at the amino-terminal end and a constant region at the carboxyl-terminal end

205 views • 18 slides

Antibodies (Immunoglobulin)

Antibodies (Immunoglobulin). Dr. Nasim PGT Biochemistry. Proteins that recognize and bind to a particular antigen with very high specificity . Made in response to exposure to the antigen. Each antibody has at least two identical sites that bind antigen: Antigen binding sites .

517 views • 14 slides