'Cooperative binding' presentation slideshows

Chapter 8 Gene Regulation in Prokaryotes

Chapter 8 Gene Regulation in Prokaryotes. TOPIC 1 Principles of Transcriptional Regulation TOPIC 2 Regulation of Transcription Initiation: Examples from Bacteria TOPIC 3 The Case of Phage ?: Layers of Regulation. TOPIC 1 Principles of Transcriptional Regulation.

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Decisions

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Lecture 6

Lecture 6. Protein-protein interactions Affinities (cases of simple and cooperative binding) Examples of Ligand-protein interactions Antibodies and their generation.

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Determination of primary structure of proteins by Edman degradation

Determination of primary structure of proteins by Edman degradation. determination of amino acid composition: hydrolysis to individual amino acids by 6 M HCl at 110 o C for 24 h amino acids can be separated then by ion-exchange chromatography

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Protein Function

Protein Function. Hemoglobin as a model systems for: Ligand binding Quaternary structure and symmetry Cooperative behavior Allosteric conformational effects Genetic variation, selection, disease. Myoglobin (a monomeric form of hemoglobin).

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Phase Equilibria

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Transfer of charged molecules

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INDM 3007

INDM 3007. Lecture 5. Rpol. This is typical for transcriptional activators. Repressor binding sites often overlap the promoter. Exception: activators of sigma-54 RNA polymerase These bind far upstream, more common for eukaryotic promoters. lysR proteins bind adjacent to the CbbR promoter.

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Mitogen-Activated Protein Kinase Pathway

Mitogen-Activated Protein Kinase Pathway. Mitogen- a compound that encourages a cell to commence division, triggering mitosis.

371 views • 11 slides