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Family based approaches

Family based approaches

Protein Annotations from Sequence Data. Methods which also exploit non-homology based information. Family based approaches. Network based analyses. Homology based inference of protein functions. ancestral protein. a. duplication. paralogues. a. b. speciation. orthologues. a. a.

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724 views • 56 slides
The evolution of domain superfamilies from a structural and functional perspective

The evolution of domain superfamilies from a structural and functional perspective

The evolution of domain superfamilies from a structural and functional perspective. Oliver Redfern CATH-GENE3D group Dept. Structural and Molecular Biology University College London UK. The CATH and Gene3D Domain and protein family resources (sequence, structure, function).

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584 views • 41 slides
Classification of protein and domain families

Classification of protein and domain families

Protein Family Resources and Protocols for Structural and Functional Annotation of Genome Sequences. Domain structures. Domain structure predictions. Classification of protein and domain families. Structure to function. Sequence to function. H. A. T. C. Fold Group (1100).

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538 views • 34 slides
Genome Analysis to Select Targets which Probe Fold and Function Space

Genome Analysis to Select Targets which Probe Fold and Function Space

Genome Analysis to Select Targets which Probe Fold and Function Space. How many protein superfamilies and families can we identify in the proteomes How many structures needed to cover a high fraction of prokaryotic, eukaryotic families

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324 views • 23 slides

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