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Important drug clearance route - PowerPoint PPT Presentation

Variability of Hepatic Drug Metabolism & Dosage Adjustment

Variability of Hepatic Drug Metabolism & Dosage Adjustment. Objectives. Discuss hepatic disease and other factors which impact hepatic drug metabolism. Review calculations of Hepatic extraction and clearance. Understand the impact of hepatic first pass extraction on oral bioavailability.

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Important drug clearance route - PowerPoint PPT Presentation

Variability of Hepatic Drug Metabolism &amp; Dosage Adjustment

Variability of Hepatic Drug Metabolism & Dosage Adjustment