'Reading frames' presentation slideshows

Viral Genomics

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Gene Prediction in silico

Gene Prediction in silico. Nita Parekh BIRC, IIIT, Hyderabad. Goal. The ultimate goal of molecular cell biology is to understand the physiology of living cells in terms of the information that is encoded in the genome of the cell How computational approaches can help

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Chapter 7

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Nothing in ( computational ) biology makes sense except in the light of evolution

Nothing in ( computational ) biology makes sense except in the light of evolution. after Theodosius Dobzhansky (1970). A brief history and some central principles of evolutionary (computational) genomics. J. Mol Biol 1982 Dec 25;162(4):729-73

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Probabilistic sequence modeling I: frequency and profiles

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The Organization of Cellular Genomes Complexity of Genomes Chromosomes and Chromatin Sequences of Genomes Bioinformatics

The Organization of Cellular Genomes Complexity of Genomes Chromosomes and Chromatin Sequences of Genomes Bioinformatics. Introduction to Cellular Genomes. The sequences of many cellular genomes are known: Bacteria Yeast Drosophila Many Plants and Animals Humans

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Designs in DNA

Designs in DNA. Richard Deem, Paradoxes Class, March 16, 2014. Transcription. Protein. Central Dogma of Biology. Nucleus. Mitochondrion. Chloroplast. DNA. T. T. C. T. C. A. T. C. G. A. A. C. A. A. A. G. A. G. G. G. G. T. A. T. C. T. C. C. C. A. G. C. A. T.

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Last lecture summary

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Chapter 4: B Cell Development

Chapter 4: B Cell Development. (Skip Figs. 4.6, 4.12) . Objectives Discover how lymphoid stem cells become B cells destined to make antibodies Understand the importance of Ig gene rearrangement Appreciate mechanisms leading to B-cell leukemias. Phases of B-cell development.

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???????. GENE CLONING & DNA ANALYSIS T. A. BROWN. Chapter 10 Studying Genomes. 12 Studying Genomes 12.1 Genome annotation 12.1.1 Identifying the genes in a genome sequence Searching for open reading frames Simple ORF scans are less effective at locating genes in eukaryotic genomes

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Translating the Genetic Code

Translating the Genetic Code. Gene expression part 3. An overview of gene expression. Figure 13.2. The Idea of A Code. 20 amino acids 4 nucleotides How do nucleic acids composed of 4 nucleotides specify the synthesis of proteins composed of 20 different amino acids?. The Coding Problem.

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Bioinformatics

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Protein databases Henrik Nielsen

Protein databases Henrik Nielsen. Background- Nucleotide databases. GenBank , http://www.ncbi.nlm.nih.gov/Genbank/ National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH), USA. EMBL , http://www.ebi.ac.uk/embl/

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Practical Bioinformatics

Practical Bioinformatics. By: Dr David P Kateete , Makerere College of Health Sciences. Bioinformatics. Molecular biology Flow/function of biological information (life) in living things (classical experiments) Bioinformatics

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More on translation

More on translation. How DNA codes proteins. The primary structure of each protein (the sequence of amino acids in the polypeptide chains that make up a protein) is represented as a sequence of codons. Each codon is a triplet of nucleotides. Traditionally, codons are

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Types of Mutations

Types of Mutations. Thanks to Ms. Sara Dozier and Ms. Kimball for many of these slides!. Mutations. Mistakes in the nucleotide sequence in the DNA of a cell Caused by: Errors during DNA replication UV light Radiation Toxic chemicals Some viruses Immune system. What is a Mutant?.

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