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ICBO 2011

ICBO 2011. Foundational Model of Anatomy (FMA). created by Dr. Cornelius Rosse (1995) ontology for the domain of human anatomy theory of anatomy: structural context r eference ontology source of computable anatomical knowledge data annotation, organization, integration,

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ICBO 2011

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  1. ICBO 2011 Foundational Model of Anatomy (FMA) • created by Dr. Cornelius Rosse (1995) • ontology for the domain of human anatomy • theory of anatomy: structural context • reference ontology • source of computable anatomical knowledge • data annotation, organization, integration, • interoperability

  2. Anatomy Taxonomy Boundary Network Anatomical Structure Anatomical ine (1-D) Cardinal Organ Part Anterior Interventricular Sulcus Organ Component Anatomical Surface -is a- Heart Cardiac Chamber Right Coronary Sulcus Sternocostal Surface bounded by Part-of Network -is a- Part_of bounded by Infundibulum Inferior margin of heart Inflow part of RV has Right Ventricle boundary of part Diaphragmatic Surface Coronary Sulcus Wall of RV Cavity of RV has adjacency bounded by has adjacency Posterior IV Sulcus Cavity of infund. Cavity of infl.part to left Anatomical point (1-D) anterior inferior inferior -is a- Left ventricle Pericardial sac Diaphragm Apex Crux of heart Spatial Association Network

  3. Foundational Model of Anatomy (FMA) • > 85,000 classes (types) • > 155,000 terms (preferred name, synonym) • > 170 relations/properties • > 2.3 million links (relationships)

  4. Protege Anatomical Structural Relation Anatomy Taxonomy (AT)

  5. Interoperability issue: Native format : frames

  6. Objectives for the translation of FMA into OWL • Interoperability with semantic web community/OBO/clinical users • enhanced expressivity in the representation • quality assurance: error and consistency checks • accessibility to modularity methods

  7. Past and current efforts: Natasha Noy - OWL Full Christine Golbreich - OWL DL, OWL 2 Robert Hoehndorf – OWL EL, OWL DL Alan Ruttenberg – OWL DL

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